Effects of a supervised exercise program on the physical fitness and immunological function of HIV-infected patients

Journal of Sports Medicine and Physical Fitness

Volumn 50, Issue 4, 2010, Pages 511-518

  Farinatti, P T V ^a,b,e,f   Borges, J P ^a   Gomes, R D ^a   Lima, D ^c   Fleck, Steven J ^d  

^a STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b SALGADO DE OLIVEIRA UNIVERSITY   (Brazil)

^c HOSPITAL UNIVERSITÁRIO PEDRO ERNESTO   (Brazil)

^d University of Colorado College of Nursing   (United States)

^e Maracanã ^*  (Brazil)

^f FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

AIDS; Antiretroviral therapy; CD4 lymphocyte count; Immune function; Physical activity

Indexed keywords

ADULT; ARTICLE; CD4 LYMPHOCYTE COUNT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EXERCISE; HEART RATE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MIDDLE AGED; MUSCLE STRENGTH; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL;

ADULT; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; CD4 LYMPHOCYTE COUNT; EXERCISE; HEART RATE; HIV INFECTIONS; HUMANS; MIDDLE AGED; MUSCLE STRENGTH;

EID: 79952607600     PISSN: 00224707     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Roberts CK, Barnard RJ. Effects of exercise and diet on chronic disease. J Appl Physiol 2005; 98:3-30. (Pubitemid 40044843)
2. Wisloff U, Nilsen TI, Droyvold WB, Morkved S, Slordahl SA, Vatten LJ. A single weekly bout of exercise may reduce cardiovascular mortality:how little pain for cardiac gain? 'The HUNT study, Norway'. Eur J Cardiovasc Prev Rehabil 2006;13:798-804.
3. Kamin DS, Grinspoon SK. Cardiac Disease in HIV-Positive Patients. AIDS 2005;19:641-52.
4. O'Brien K, Nixon S, Tynan AM, Glazier RH. Effectiveness of aerobic exercise in adults living with HIV/AIDS:systematic review. Med Sci Sports Exerc 2004;36:1659-66. (Pubitemid 39332281)
5. Carr A, Samaras K, Chisholm DJ, Cooper DA. Pathogenesis of HIV-1-protease inhibitor-associated peripheral lipodystrophy, hyperlipidaemia, and insulin resistance. Lancet 1998;352:1881-3. (Pubitemid 28279721)
6. Ciccolo JT, Jowers EM, Bartholomew JB. The benefits of exercise training for quality of life in HIV/AIDS in the post-HAART era. Sports Med 2004;34:487-99. (Pubitemid 38981842)
7. World Health Organization. International Classification of Functioning, Disability and Health: ICF Short Version. Geneva: WHO; 2001.
8. Safrin S, Grunfeld C. Fat Distribution and Metabolic Changes in Patients with HIV Infection. AIDS 1999;13:2493-505. (Pubitemid 30038027)
9. Serrano S, Marinoso ML, Soriano JC, Rubies-Prat J, Aubia J, Coll J et al. Bone remodelling in human immunodeficiency virus-1-infected patients. A histomorphometric study. Bone 1995; 16:185-91.
10. Vella S. Future treatment perspectives. J Acquir Immune Defic Syndr 2003;34:S95-S100. (Pubitemid 37158640)
11. Agin D, Gallagher D, Wang J, Heymsfield SB, Pierson RN, Kotler DP. Effects of whey protein and resistance exercise on body cell mass, muscle strength, and quality of life in women with HIV. AIDS 2001; 15: 2431-40. (Pubitemid 34014612)
12. MacArthur RD, Levine SD, Birk TJ. Supervised exercise training improves cardiopulmonary fitness in HIV-infected persons. Med Sci Sports Exerc 1993; 25:684-8. (Pubitemid 23170108)
13. Rigsby LW, Dishman RK, Jackson AW, Maclean GS, Raven PB. Effects of exercise training on men seropositive for the human immunodeficiency virus-1. Med Sci Sports Exerc 1992;24:6-12.
14. Roubenoff R, McDermott A, Weiss L, Suri J, Wood M, Bloch R et al. Short-term progressive resistance training increases strength and lean body mass in adults infected with human immunodeficiency virus. AIDS 1999; 13:231-9. (Pubitemid 29050411)
15. Roubenoff R, Wilson IB. Effect of resistance training on self reported physical functioning in HIV infection. Med Sci Sports Exerc 2001; 33:1811-7. (Pubitemid 33035474)
16. Stringer WW, Berezovskaya M, O'Brien WA, Beck CK, Casaburi R. The effect of exercise training on aerobic fitness, immune indices, and quality of life in HIV+ patients. Med Sci Sports Exerc 1998;30:11-6. (Pubitemid 28071378)
17. Stringer WW. Mechanisms of exercise limitation in HIV+ individuals. Med Sci Sports Exerc 2000;32(Suppl 7):S412-21.
18. Terry L, Sprinz E, Stein R, Medeiros NB, Oliveira J, Ribeiro JP. Exercise training in HIV-I-infected individuals with dyslipidemia and lipodystrophy. Med Sei Sports Exerc 2006; 38:411-7. (Pubitemid 43364114)
19. Yarasheski KE, Roubenoff R. Exercise treatment for HIV-associated metabolic and anthropomorphic complications. Exerc Sport Sci Rev 2001; 29:170-4. (Pubitemid 33596399)
20. O'Brien K, Nixon S, Glazier RH, Tynan AM. Progressive resistive exercise interventions for adults living with HIV/AIDS. Cochrane Database Syst Rev 2004;4:CD004248.
21. Nieman CD. Exercise, Infection, and Immunity. Int J Sports Med 1996;15(Suppl3):S131-41.
22. Nieman CD, Henson DA, Sampson CS, Herring JL, Suttles J, Conley M et al. The Acute Immune Response to Exhaustive Resistance Exercise. Int J Sports Med 1995;16:322-8.
23. Farinatti PTV. Oliveira RB, Pinto VLM, Monteiro WD, Francischetti E. Home exercise program:short term effects on physical aptitude and blood pressure in hypertensive individuals. Arq Bras Cardiol 2005;84:473-9. (Pubitemid 40874025)
24. Wells KF, Dillon EK. The sit and reach - A test of back and leg flexibility. Res Quart 1952; 23:115-8.
25. Cohen J. Statistical Power Analysis for the Behavioral Sciences (2ed). Hillsdale, NJ:Lawrence Erlbaum Associates, 1988.
26. Bhasin S, Storer TW, Javanbakht M, Berman N, Yarasheski KE, Phillips J et al. Testosterone replacement and resistance exercise in HIV-infected men with weight loss and low testosterone levels. JAMA 2000;283:763-70. (Pubitemid 30084616)
27. Fairfield WP, Treat M, Rosenthal DI, Frontera W, Stanley T, Corcoran C et al. Effects of testosterone and exercise on muscle leanness in eugonadal men with AIDS wasting. J Appl Physiol 2001; 90:2166-71. (Pubitemid 32467408)
28. Grinspoon S, Corcoran C, Parlman K, Costello M, Rosenthal D, Anderson E et al. Effects of testosterone and progressive resistance training in eugonadal men with AIDS wasting:a randomized, controlled trial. Ann Intern Med 2000; 133:348-55.
29. Dudgeon WD, Phillips KD, Carson JA, Brewer RB, Durstine JL, Hand GA. Counteracting muscle wasting in HIV-infected individuals. HIV Med 2006;7:299-310. (Pubitemid 43805690)
30. Lox CL, McAuley E, Tucker RS. Aerobic and resistance exercise training effects on body composition, muscular strength, and cardiovascular fitness in an HIV-1 population. Int J Behav Med 1996;3:55-69. (Pubitemid 126488631)
31. Robinson FP, Quinn LT, Rimmer JH. Effects of high-intensity endurance and resistance exercise on HIV metabolic abnormalities:a pilot study. Biol Res Nurs 2007;8:177-85. (Pubitemid 44893420)
32. Dolan SE, Frontera W, Librizzi J, Ljungquist K, Juan S, Dorman R et al. Effects of a supervised home-based aerobic and progressive resistance training regimen in women infected with human immunodeficiency virus:a randomized trial. Arch Intern Med 2006; 166: 1225-31. (Pubitemid 43877633)
33. Thoni GJ, Fedou C, Brun JF, Fabre J, Renard E, Reynes J et al. Reduction of fat accumulation and lipid disorders by individualized light aerobic training in human immunodeficiency virus infected patients with lipodystrophy and/or dyslipidemia. Diabetes Metab 2002; 28: 397-404. (Pubitemid 35434314)
34. Sattler FR, Jaque SV, Schroeder ET, Olson C, Dube MP, Martinez C et al. Effects of pharmacological doses of nandrolone decanoate and progressive resistance training in immunodeficient patients infected with human immunodeficiency virus. J Clin Endocrinol Metab 1999;84:1268-76. (Pubitemid 30644388)
35. Esposito F, Impellizzeri FM, Margonato V, Vanni R, Pizzini G, Veic-steinas A. Validity of heart rate as an indicator of aerobic demand during soccer activities in amateur soccer players. Eur J Appl Physiol 2004; 93:167-72. (Pubitemid 39485594)
36. Rowland TW, Rambusch JM, Staab JS, Unnithan VB, Siconolfi SF. Accuracy of physical working capacity (PWC 170) in estimating aerobic fitness in children. J Sports Med Phys Fitness 1993;33:184-8. (Pubitemid 23280820)
37. De Vito G, Hernandez R, Gonzalez V, Felici F, Figura F. Low intensity physical training in older subjects. J Sports Med Phys Fit 1997;37:72-7. (Pubitemid 27242714)
38. Hamdorf PA, Withers RT, Penhall RK, Haslam MV. Physical training effects on the fitness and habitual activity patterns of elderly women. Arch Phys Med Rehabil 1992; 73:603-8.
39. Wajngarten M, Negrãeo CE, Kalil LMP, Ramires PR, Rondon E, Haebisch H et al. Influence of aging and exercise training on the increase in oxygen uptake as a function of the increase in work rate. Cardiol Elder 1994;2: 421-6.
40. LewalterT, MacCarter D, Jung W, Schimpf R, Manz M, Lüderitz B. Heart rate to work rate relation throughout peak exercise in normal subjects as a guideline for rate-adaptive pacemaker programming. Am J Cardiol 1995 15;76:812-6.
41. Carta P, Aru G, Barbieri MT, Mele M. Bicycle ergometry exercise tests:a comparison between 3 protocols with an increasing load. Med Lav 1991; 82:56-64.
42. Lewis SF, Taylor WF, Graham RM, Pettinger WA, Shutte JE, Blomqvist CG. Cardiovascular responses to exercise as functions of absolute and relative work load. J Appl Physiol 1983;54:1314-23. (Pubitemid 13098982)
43. Smith BA, Neidig JL, Nickel JT, Mitchell GL, Para MF, Fass RJ. Aerobic exercise:effects on parameters related to fatigue, dyspnea, weight and body composition in HIV-infected adults. AIDS 2001;15:693-701. (Pubitemid 32423216)
44. Cackett P, Weir CR, McFadzean R, Seaton RA. Optic Neuropathy without Retinopathy in AIDS and Cytomegalovirus Infection (Letter). J Neuro-Ophthalmol 2004;24:94-5. (Pubitemid 38381229)
45. Stringer WW. HIV and Aerobic Exercise:Current Recommendations. Sports Med 1999; 28:389-95.
46. García F, Lazzari E, Plana M, Castro P, Mestre G, Nomdedeu M et al. Long-term CD4+ T-cell response to highly active antiretroviral therapy according to baseline CD4+ T-cell count. J Acquir Immune Defic Syndr 2004; 36:702-13. (Pubitemid 38685964)
47. Volberding PA. Initiating HIV therapy. Timing is critical, controversial. Postgrad Med 2004; 115:15-26.
48. Shephard RJ. Exercise, immune function and HIV infection. J Sports Med Phys Fitness 1998;38:101-10. (Pubitemid 28527191)
49. Mustafa T, Sy FS, Macera CA, Thompson SJ, Jackson KL, Selassie A et al. Association between exercise and HIV disease progression in a cohort of homosexual men. Ann Epidemiol 1999; 9:127-31. (Pubitemid 29072771)