Effects of High-Intensity Endurance and Resistance Exercise on HIV Metabolic Abnormalities: A Pilot Study

Biological Research for Nursing

Volumn 8, Issue 3, 2007, Pages 177-185

  Robinson, F Patrick ^a   Quinn, Lauretta T ^a   Rimmer, James H ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Adiposity; Exercise; HIV; Insulin resistance; Lipids; Lipodystrophy; Metabolism

Indexed keywords

LIPID;

ADULT; ANTHROPOMETRY; ARTICLE; BLOOD; BODY COMPOSITION; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED CLINICAL TRIAL; ENDURANCE; EXERCISE TOLERANCE; FEMALE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HIV ASSOCIATED LIPODYSTROPHY; HUMAN; INSULIN RESISTANCE; KINESIOTHERAPY; MALE; METABOLISM; METHODOLOGY; OXYGEN CONSUMPTION; PILOT STUDY; RADIODENSITOMETRY; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; TREATMENT OUTCOME; WEIGHT LIFTING;

ADULT; ANTHROPOMETRY; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; BODY COMPOSITION; DENSITOMETRY, X-RAY; EXERCISE THERAPY; EXERCISE TOLERANCE; FEMALE; HIV-ASSOCIATED LIPODYSTROPHY SYNDROME; HUMANS; INSULIN RESISTANCE; LIPIDS; MALE; OXYGEN CONSUMPTION; PHYSICAL ENDURANCE; PILOT PROJECTS; RANDOMIZED CONTROLLED TRIALS; RESEARCH DESIGN; RISK FACTORS; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME; WEIGHT LIFTING;

EID: 33845417218     PISSN: 10998004     EISSN: 15524175     Source Type: Journal    
DOI: 10.1177/1099800406295520     Document Type: Article

References (45)

1. American College of Sports Medicine, & Roitman, J. L. (2001). ACSM's resource manual for guidelines for exercise testing and prescription (4th ed.). Baltimore: Lippincott Williams & Wilkins.
2. Berg, K. M., Demas, P. A., Howard, A. A., Schoenbaum, E. E., Gourevitch, M. N., & Arnsten, J. H. (2004). Gender differences in factors associated with adherence to antiretroviral therapy. Journal of General Internal Medicine, 19, 1111-1117.
3. Blake, G. L., Wahner, H. W., & Fogelman, I. (1999). The evaluation of osteoporosis: Dual energy X-ray absorptiometry and ultrasound in clinical practise. London: Martin Dunitz.
4. Bonora, E., Targher, G., Alberiche, M., Bonadonna, R. C., Saggiani, F., Zenere, M. B., et al. (2000). Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: studies in subjects with various degrees of glucose tolerance and insulin sensitivity. Diabetes Care, 23, 57-63.
5. Borkan, G. A., Gerzof, S. G., Robbins, A. H., Hults, D. E., Silbert, C. K., & Silbert, J. E. (1982). Assessment of abdominal fat content by computed tomography. American Journal of Clinical Nutrition, 36, 172-177.
6. Bozzette, S. A., Ake, C. F., Tam, H. K., Chang, S. W., & Louis, T. A. (2003). Cardiovascular and cerebrovascular events in patients treated for human immunodeficiency virus infection. New England Journal of Medicine, 348, 702-710.
7. Buemann, B., & Tremblay, A. (1996). Effects of exercise training on abdominal obesity and related metabolic complications. Sports Medicine, 21, 191-212.
8. Carpinelli, R. N., & Otto, R. M. (1998). Strength training: Single versus multiple sets. Sports Medicine, 26, 73-84.
9. Catz, S. L., Kelly, J. A., Bogart, L. M., Benotsch, E. G., & McAuliffe, T. L. (2000). Patterns, correlates, and barriers to medication adherence among persons prescribed new treatments for HIV disease. Health Psychology, 19, 124-133.
10. DeNino, W. F., Tchernof, A., Dionne, I. J., Toth, M. J., Ades, P. A., Sites, C. K., et al. (2001). Contribution of abdominal adiposity to age-related differences in insulin sensitivity and plasma lipids in healthy nonobese women. Diabetes Care, 24, 925-932.
11. Driscoll, S. D., Meininger, G. E., Lareau, M. T., Dolan, S. E., Killilea, K. M., Hadigan, C. M., et al. (2004). Effects of exercise training and metformin on body composition and cardiovascular indices in HIV-infected patients. AIDS, 18, 465-473.
12. Driscoll, S. D., Meininger, G. E., Ljungquist, K., Hadigan, C., Torriani, M., Klibanski, A., et al. (2004). Differential effects of metformin and exercise on muscle adiposity and metabolic indices in human immunodeficiency virus-infected patients. Journal of Clinical Endocrinology & Metabolism, 89, 2171-2178.
13. Durstine, J. L., Grandjean, P. W., Davis, P. G., Ferguson, M. A., Alderson, N. L., & DuBose, K. D. (2001). Blood lipid and lipoprotein adaptations to exercise: A quantitative analysis. Sports Medicine, 31, 1033-1062.
14. El-Sadr, W. M., Mullin, C. M., Carr, A., Gibert, C., Rappoport, C., Visnegarwala, F., et al. (2005). Effects of HIV disease on lipid, glucose and insulin levels: Results from a large anti-retroviral-naive cohort. HIV Medicine, 6, 114-121.
15. Franklin, B. A. (Ed.). (2000). ACSM's guidelines for exercise testing and prescription (6th ed.). Philadelphia: Lippincott Williams & Wilkins.
16. Garcia-Estevez, D. A., Araujo-Vilar, D., Fiestras-Janeiro, G., Saavedra-Gonzalez, A., & Cabezas-Cerrato, J. (2003). Comparison of several insulin sensitivity indices derived from basal plasma insulin and glucose levels with minimal model indices. Hormone & Metabolic Research, 35, 13-17.
17. Grinspoon, S., & Carr, A. (2005). Cardiovascular risk and body-fat abnormalities in HIV-infected adults. New England Journal of Medicine, 352, 48-62.
18. Grinspoon, S. K. (2005). Metabolic syndrome and cardiovascular disease in patients with human immunodeficiency virus. American Journal of Medicine, 118 (Suppl. 2). 23S - 28S.
19. Hadigan, C., Corcoran, C., Basgoz, N., Davis, B., Sax, P., & Grinspoon, S. (2000). Metformin in the treatment of HIV lipodystrophy syndrome: A randomized controlled trial. Journal of the American Medical Association, 284, 472-477.
20. Hadigan, C., Meigs, J. B., Corcoran, C., Rietschel, P., Piecuch, S., Basgoz, N., et al. (2001). Metabolic abnormalities and cardiovascular disease risk factors in adults with human immunodeficiency virus infection and lipodystrophy. Clinical Infectious Diseases, 32, 130-139.
21. Ivy, J. L. (1997). Role of exercise training in the prevention and treatment of insulin resistance and non-insulin-dependent diabetes mellitus. Sports Medicine, 24, 321-336.
22. Jones, S. P., Doran, D. A., Leatt, P. B., Maher, B., & Pirmohamed, M. (2001). Short-term exercise training improves body composition and hyperlipidaemia in HIV-positive individuals with lipodystrophy. AIDS, 15, 2049-2051.
23. Kvist, H., Chowdhury, B., Grangard, U., Tylen, U., & Sjostrom, L. (1988). Total and visceral adipose-tissue volumes derived from measurements with computed tomography in adult men and women: Predictive equations. American Journal of Clinical Nutrition, 48, 1351-1361.
24. Lichtenstein, K. A., Ward, D. J., Moorman, A. C., Delaney, K. M., Young, B., Palella, F. J., Jr., et al. (2001). Clinical assessment of HIV-associated lipodystrophy in an ambulatory population. AIDS, 15, 1389-1398.
25. Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F., & Turner, R. C. (1985). Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia, 28, 412-419.
26. Palella, F. J., Baker, R., Moorman, A. C., Chmiel, J. S., Wood, K. C., & Holmberg, S. D. (2004, February). Mortality and morbidity in the HAART era: Changing causes of death and disease in the HIV outpatient study. Paper presented at the 11th Conference on Retroviruses and Opportunistic Infections, San Francisco.
27. Palella, F. J., Delaney, K. M., Moorman, A. C., Loveless, M. O., Fuhrer, J., Satten, G. A., et al. (1998). Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. New England Journal of Medicine, 338, 853-860.
28. Poehlman, E. T., Dvorak, R. V., DeNino, W. F., Brochu, M., & Ades, P. A. (2000). Effects of resistance training and endurance training on insulin sensitivity in nonobese, young women: A controlled randomized trial. Journal of Clinical Endocrinology & Metabolism, 85, 2463-2468.
29. Pritchard, J. E., Nowson, C. A., Strauss, B. J., Carlson, J. S., Kaymakci, B., & Wark, J. D. (1993). Evaluation of dual energy X-ray absorptiometry as a method of measurement of body fat. European Journal of Clinical Nutrition, 47, 216-228.
30. Riddler, S. A., Smit, E., Cole, S. R., Li, R., Chmiel, J. S., Dobs, A., et al. (2003). Impact of HIV infection and HAART on serum lipids in men. Journal of the American Medical Association, 289, 2978-2982.
31. Robinson, F. P. (2004). HIV lipodystrophy syndrome: A primer. Journal of the Association of Nurses in AIDS Care, 15, 15-29.
32. Ross, R., Freeman, J. A., & Janssen, I. (2000). Exercise alone is an effective strategy for reducing obesity and related comorbidities. Exercise & Sport Sciences Reviews, 28, 165-170.
33. Roubenoff, R., McDermott, A., Weiss, L., Suri, J., Wood, M., Bloch, R., et al. (1999). Short-term progressive resistance training increases strength and lean body mass in adults infected with human immunodeficiency virus. AIDS, 13, 231-239.
34. Roubenoff, R., Weiss, L., McDermott, A., Heflin, T., Cloutier, G. J., Wood, M., et al. (1999). A pilot study of exercise training to reduce trunk fat in adults with HIV-associated fat redistribution. AIDS, 13, 1373-1375.
35. Shlay, J. C., Visnegarwala, F., Bartsch, G., Wang, J., Peng, G., El-Sadr, W. M., et al. (2005). Body composition and metabolic changes in antiretroviral-naive patients randomized to didanosine and stavudine vs. abacavir and lamivudine. Journal of Acquired Immune Deficiency Syndromes, 38, 147-155.
36. Simoneau, J. A., Colberg, S. R., Thaete, F. L., & Kelley, D. E. (1995). Skeletal muscle glycolytic and oxidative enzyme capacities are determinants of insulin sensitivity and muscle composition in obese women. FASEB Journal, 9, 273-278.
37. Smith, B. A., Neidig, J. L., Nickel, J. T., Mitchell, G. L., Para, M. F., & Fass, R. J. (2001). Aerobic exercise: Effects on parameters related to fatigue, dyspnea, weight and body composition in HIV-infected adults. AIDS, 15, 693-701.
38. Thaete, F. L., Colberg, S. R., Burke, T., & Kelley, D. E. (1995). Reproducibility of computed tomography measurement of visceral adipose tissue area. International Journal of Obesity & Related Metabolic Disorders, 19, 464-467.
39. Thoni, G. J., Fedou, C., Brun, J. F., Fabre, J., Renard, E., Reynes, J., et al. (2002). Reduction of fat accumulation and lipid disorders by individualized light aerobic training in human immunodeficiency virus infected patients with lipodystrophy and/or dyslipidemia. Diabetes & Metabolism, 28, 397-404.
40. van Servellen, G., & Lombardi, E. (2005). Supportive relationships and medication adherence in HIV-infected, low-income Latinos. Western Journal of Nursing Research, 27, 1023-1039.
41. Visnegarwala, F., Maldonado, M., Sajja, P., Minihan, J. L., Rodriguez-Barradas, M. C., Ong, O., et al. (2004). Lipid lowering effects of statins and fibrates in the management of HIV dyslipidemias associated with antiretroviral therapy in HIV clinical practice. Journal of Infection, 49, 283-290.
42. Wallace, T. M., Levy, J. C., & Matthews, D. R. (2004). Use and abuse of HOMA modeling. Diabetes Care, 27, 1487-1495.
43. Wang, Z. M., Visser, M., Ma, R., Baumgartner, R. N., Kotler, D., Gallagher, D., et al. (1996). Skeletal muscle mass: Evaluation of neutron activation and dual-energy X-ray absorptiometry methods. Journal of Applied Physiology, 80, 824-831.
44. Wellens, R., Chumlea, W. C., Guo, S., Roche, A. F., Reo, N. V., & Siervogel, R. M. (1994). Body composition in white adults by dual-energy X-ray absorptiometry, densitometry, and total body water. American Journal of Clinical Nutrition, 59, 547-555.
45. Yarasheski, K. E., Tebas, P., Stanerson, B., Claxton, S., Marin, D., Bae, K., et al. (2001). Resistance exercise training reduces hypertriglyceridemia in HIV-infected men treated with antiviral therapy. Journal of Applied Physiology, 90, 133-138.