Starfish, Asterias amurensis and Asterina pectinifera, as potential sources of th1 immunity-stimulating adjuvants

Journal of Veterinary Medical Science

Volumn 73, Issue 2, 2011, Pages 227-229

  Kawase, Osamu ^a   Goo, Youn Kyoung ^b   Jujo, Hayato ^b   Nishikawa, Yoshifumi ^b   Xuan, Xuenan ^b  

^a Shizugawa Nature Center   (Japan)

^b OBIHIRO UNIVERSITY OF AGRICULTURE AND VETERINARY MEDICINE   (Japan)

Author keywords

Adjuvant; Saponin; Starfish; Th1 immunity; Vaccine

Indexed keywords

IMMUNOGLOBULIN G; IMMUNOLOGICAL ADJUVANT; OVALBUMIN; SAPONIN;

ANIMAL; BLOOD; CHEMISTRY; FEMALE; IMMUNOLOGY; ISOLATION AND PURIFICATION; MOUSE; NOTE; STARFISH; TH1 CELL; TH2 CELL;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; FEMALE; IMMUNOGLOBULIN G; MICE; OVALBUMIN; SAPONINS; STARFISH; TH1 CELLS; TH2 CELLS;

ASTERIAS AMURENSIS; ASTERINA PECTINIFERA; ASTEROIDEA; MUS;

EID: 79952595144     PISSN: 09167250     EISSN: 13477439     Source Type: Journal    
DOI: 10.1292/jvms.10-0163     Document Type: Note

References (16)

1. Cox, J. C. and Coulter, A. R. 1997. Adjuvants-a classification and review of their modes of action. Vaccine 15: 248-256.
2. Kensil, C. R., Patel, U., Lennick, M. and Marciani, D. 1991. Separation and characterization of saponins with adjuvant activity from Quillaja saponaria Molina cortex. J. Immunol. 146: 431-437.
3. Kicha, A. A., Ivanchina, N. V. and Stonik, V. A. 2004. Seasonal variations in polyhydroxysteroids and related glycosides from digestive tissue of the starfish Patiria (=Asterina) pectinifera. Comp. Biochem. Physiol. B 139: 581-585.
4. Leclerc, C. 2003. New approaches in vaccine development. Comp. Immunol. Microbiol. Infect. Dis. 26: 329-341.
5. Liu, G., Anderson, C., Scaltreto, H., Barbon, J. and Kensil, C. R. 2002. QS-21 structure/function studies: effect of acylation on adjuvant activity. Vaccine 20: 2808-2815.
6. Marciani, D. J., Pathak, A. K., Reynolds, R. C., Seitz, L. and May, R. D. 2001. Altered immunomodulating and toxicological properties of degraded Quillaja saponaria Molina saponins. Int. Immunopharmacol. 1: 813-818.
7. Matsuno, T. and Ishida, T. 1969. Distribution and seasonal variation of toxic principles of sea-cucumber (Holothuria leucospilota Brandt). Experientia 25: 1261.
8. Pascual, D. M., Morales, R. D., Gil, E. D., Muñoz, L. M., López, J. E. and Casanueva, O. L. J. 2006. Adjuvants: present regulatory challenges. Vaccine 24: 88-89.
9. Ramon, G. 1924. Sur la toxine et sur l'anatoxine diphtheriques. Ann. Inst. Pasteur 38: 1-10 (in French).
10. Scheuer, P. J. 1971. Toxins from marine invertebrates. Naturwissenschaften 58: 549-554.
11. Sparg, S. G., Light, M. E. and van Staden, J. 2004. Biological activities and distribution of plant saponins. J. Ethnopharmacol. 94: 219-243.
12. Sun, H. X., Xie, Y. and Ye, Y. P. 2009. Advances in saponinbased adjuvants. Vaccine 27: 1787-1796.
13. Sun, H. X., Ye, Y. P., Pan, H. J. and Pan, Y. J. 2004. Adjuvant effect of Panax notoginseng saponins on the immune responses to ovalbumin in mice. Vaccine 22: 3882-3889.
14. Wack, A., Baudner, B. C., Hilbert, A. K., Manini, I., Nuti, S. and Tavarini, S. 2008. Combination adjuvants for the induction of potent, long-lasting antibody and T-cell responses to influenza vaccine in mice. Vaccine 26: 552-561.
15. Waite, D. C., Jacobson, E. W., Ennis, F. A., Edelman, R., White, B., Kammer, R., Anderson, C. and Kensil, C. R. 2001. Three double-blind, randomized trials evaluating the safety and tolerance of different formulations of the saponin adjuvant QS- 21. Vaccine 19: 3957-3967.
16. Zhang, G., Huong, V. T., Battur, B., Zhou, J., Zhang, H., Liao, M., Kawase, O., Lee, E. G., Dautu, G., Igarashi, M., Nishikawa, Y. and Xuan, X. 2007. A heterologous prime-boost vaccination regime using DNA and a vaccinia virus, both expressing GRA4, induced protective immunity against Toxoplasma gondii infection in mice. Parasitology 134: 1339-1346.