Determination of curcumin in rat plasma by liquid-liquid extraction using LC-MS/MS with electrospray ionization: assay development, validation and application to a pharmacokinetic study

Journal of Bioanalysis and Biomedicine

Volumn 2, Issue 4, 2010, Pages 79-84

  Singh, S P ^a   Wahajuddin, ^a   Jain, G K ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Curcumin; LC MS MS; Pharmacokinetics; Rat plasma; Validation

Indexed keywords

ACETONITRILE; AMMONIUM ACETATE; BIOCHANIN A; CURCUMIN;

ACCURACY; ANALYTIC METHOD; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG HALF LIFE; DRUG STABILITY; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MALE; NONHUMAN; PROCESS DEVELOPMENT; PROCESS MONITORING; PROCESS OPTIMIZATION; PRODUCT RECOVERY; RAT; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; VALIDATION PROCESS;

EID: 79952588909     PISSN: None     EISSN: 1948593X     Source Type: Journal    
DOI: 10.4172/1948-593X.1000027     Document Type: Article

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