Imaging cellular markers of neuroinflammation in the brain of the rat model of amyotrophic lateral sclerosis

Acta Physiologica Hungarica

Volumn 98, Issue 1, 2011, Pages 27-31

  Bataveljic D ^a   Stamenkovic S ^a   Bacic G ^a   Andjus, Pavle R ^a  

^a UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

amyotrophic lateral sclerosis; bloodbrain barrier; brainstem; confocal microscopy; hippocampus; magnetic resonance imaging; microglia; T cells; ultra small particles of iron oxide

Indexed keywords

CELL MARKER; GADOLINIUM; GADOLINIUM PENTETATE; NANOPARTICLE; ULTRASMALL SUPERPARAMAGNETIC IRON OXIDE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN STEM; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ACTIVATION; CELL FUSION; CELL INTERACTION; CELL LABELING; HIPPOCAMPUS; IMMUNOCOMPETENT CELL; IMMUNOCYTOCHEMISTRY; LYMPHOCYTIC INFILTRATION; MESENCEPHALON; MICROGLIA; MUTATION; NERVE CELL; NERVE CELL DEGENERATION; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PHAGOCYTE; RAT;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BIOLOGICAL MARKERS; BRAIN; DEXTRANS; ENCEPHALITIS; IMMUNOHISTOCHEMISTRY; MAGNETIC RESONANCE IMAGING; MAGNETITE NANOPARTICLES; MICROGLIA; MOTOR NEURONS; RATS; T-LYMPHOCYTES;

EID: 79952578338     PISSN: 0231424X     EISSN: 15882683     Source Type: Journal    
DOI: 10.1556/APhysiol.98.2011.1.4     Document Type: Article

References (7)

1. Andjus PR, Bataveljic D, Vanhoutte G, Mitrecic D, Pizzolante F, Djogo N, Nicaise C, Kengne FG, Gangitano C, Michetti F, Van der Linden A, Pochet R, Bacic G: In vivo morphological changes in animal models of amyotrophic lateral sclerosis and Alzheimer's-like disease: MRI approach. Anat. Rec. 292, 1882-1892 (2009)
2. Bataveljic D, Djogo N, Zupunski Lj, Bajic A, Nicaise C, Pochet R, Bacic G, Andjus PR: Live monitoring of brain damage in the rat model of amyotrophic lateral sclerosis. Gen. Physiol. Biophys. 28, 212-218 (2009)
3. Beers DR, Henkel JS, Zhao W, Wang J, Appel SH: CD4+ T-cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS. Proc. Natl. Acad. Sci. U. S. A. 105, 15558-15563 (2008)
4. Boillee S, Yamanaka K, Lobsiger CS, Copeland NG, Jenkins NA, Kassiotis G, Kollias G, Cleveland DW: Onset and progression in inherited ALS determined by motor neurons and microglia. Science 312, 1389-1392 (2006) (Pubitemid 43839552)
5. Bruijn LI, Miller TM, Cleveland DW: Unraveling the mechanisms involved in motor neuron degeneration in ALS. Annu. Rev. Neurosci. 27, 723-749 (2004) (Pubitemid 39050419)
6. Pirko I, Ciric B, Johnson AJ, Gamez J, Rodriguez M, Macura S: Magnetic resonance imaging of immune cells in inflammation of central nervous system. Croat. Med. J. 44, 463-468 (2003) (Pubitemid 37092806)
7. Zhong Z, Deane R, Ali Z, Parisi M, Shapovalov Y, O'Banion MK, Stojanovic K, Sagare A, Boillee S, Cleveland DW, Zlokovic BV: ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration. Nat. Neurosci. 11, 420-422 (2008) (Pubitemid 351441888)