Novel and efficient synthesis of 22-alkynyl-13,24(23)-cyclo-18,21- dinorchol-22-en-20(23)-one analogues

Steroids

Volumn 76, Issue 5, 2011, Pages 491-496

  Wang, Cunde ^a   Liu, Lanhai ^a   Xu, Hangxian ^a   Zhang, Zonglei ^a   Wang, Xingbin ^a   Liu, Hui ^a  

^a YANGZHOU UNIVERSITY   (China)

Author keywords

Cuprous iodide; Cyclo 18,21 dinorcholenones; Iodine; Palladium(0) catalyst; Sonogashira reaction

Indexed keywords

(3ALPHA,5ALPHA) 3 HYDROXY 22 [3 (3 HYDROXY 3 METHYLBUT 1 YNYL)] 13,23 CYCLO 18,21 DINORCHOL 22 EN 23 ONE; (3ALPHA,5ALPHA) 3 HYDROXY 22 [3 (3 HYDROXYBUT 1 YNYL)] 13,23 CYCLO 18,21 DINORCHOL 22 EN 23 ONE; (3ALPHA,5ALPHA) 3 HYDROXY 22 [3 (3 HYDROXYPROP 1 YNYL)] 13,23 CYCLO 18,21 DINORCHOL 22 EN 23 ONE; (3ALPHA,5ALPHA) 3 HYDROXY 22 [3 (4 METHYLPENT 1 YNYL)] 13,23 CYCLO 18,21 DINORCHOL 22 EN 23 ONE; (3ALPHA,5ALPHA) 3 HYDROXY 22 [3 [2 (1 HYDROXYCYCLOHEXYL)ETHYNYL]] 13,23 CYCLO 18,21 DINORCHOL 22 EN 23 ONE; (3ALPHA,5ALPHA) 3 HYDROXY 22 IODO 13,23 CYCLO 18,21 DINORCHOL 22 EN 20 ONE; (3ALPHA,5BETA) 3 HYDROXY 22 [3 (3 HYDROXYBUT 1 YNYL)] 13,24 CYCLO 18,21 DINORCHOL 22 EN 20 ONE; (3ALPHA,5BETA) 3 HYDROXY 22 [3 [2 (1 HYDROXYCYCLOHEXYL)ETHYNYL]] 13,24 CYCLO 18,21 DINORCHOL 22 EN 20 ONE; (3ALPHA,5BETA) 3 HYDROXY 22 IODO 13,24 CYCLO 18,21 DINORCHOL 22 EN 20 ONE; (3BETA,5ALPHA) 3 HYDROXY 22 [3 (3 HYDROXY 3 METHYLBUT 1 YNYL)] 13,24 CYCLO 18,21 DINORCHOL 22 EN 20 ONE; (3BETA,5ALPHA) 3 HYDROXY 22 IODO 13,24 CYCLO 18,21 DINORCHOL 22 EN 20 ONE; 22 IODOCYCLO 18,21 DINORCHOLENONE DERIVATIVE; ALKYNE; CUPROUS IODIDE; CUPROUS ION; DOXORUBICIN; PALLADIUM; STEROID; TETRAKIS(TRIPHENYLPHOSPHINE)PALLADIUM; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CROSS COUPLING REACTION; CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; PROTON NUCLEAR MAGNETIC RESONANCE; SONOGASHIRA REACTION;

ALKYNES; CELL LINE, TUMOR; CELL PROLIFERATION; CHOLENES; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79952574757     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2011.01.005     Document Type: Article

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