Reelin and human nodular heterotopia

Epilepsia

Volumn 52, Issue 3, 2011, Pages 650-652

  Thom, Maria ^a   Garbelli, Rita ^b   Spreafico, Roberto ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b DEPARTMENT OF NEUROSURGERY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

REELIN;

BRAIN CELL; BRAIN DEVELOPMENT; BRAIN MALFORMATION; CELL MIGRATION; EPILEPSY; HUMAN; LETTER; NEUROPATHOLOGY; NONHUMAN; PERIVENTRICULAR HETEROTOPIA; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; SUBCORTICAL NODULAR HETEROTOPIA;

CELL ADHESION MOLECULES, NEURONAL; CELL DIFFERENTIATION; CELL MOVEMENT; CEREBRAL CORTEX; CONTRACTILE PROTEINS; EXTRACELLULAR MATRIX PROTEINS; HUMANS; MALFORMATIONS OF CORTICAL DEVELOPMENT; MICROFILAMENT PROTEINS; MUTATION; NEOCORTEX; NERVE TISSUE PROTEINS; NEURONS; PERIVENTRICULAR NODULAR HETEROTOPIA; PHENOTYPE; SERINE ENDOPEPTIDASES; TELENCEPHALON;

EID: 79952556890     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2010.02977.x     Document Type: Letter

References (14)

1. D'Arcangelo G, Miao GG, Chen SC, Soares HD, Morgan JI, Curran T. (1995) A protein related to extracellular matrix proteins deleted in the mouse mutant reeler. Nature 374:719-723.
2. Frotscher M. (2010) Role for Reelin in stabilizing cortical architecture. Trends Neurosci 33:407-414.
3. Garbelli R, Rossini L, Moroni RF, Watakabe A, Yamamori T, Tassi L, Bramerio M, Russo GL, Frassoni C, Spreafico R. (2009) Layer-specific genes reveal a rudimentary laminar pattern in human nodular heterotopia. Neurology 73:746-753.
4. Guerrini R, Dobyns WB, Barkovich AJ. (2008) Abnormal development of the human cerebral cortex: genetics, functional consequences and treatment options. Trends Neurosci 31:154-162.
5. Haas CA, Frotscher M. (2010) Reelin deficiency causes granule cell dispersion in epilepsy. Exp Brain Res 200:141-149.
6. Hong SE, Shugart YY, Huang DT, Shahwan SA, Grant PE, Hourihane JO, Martin ND, Walsh CA. (2000) Autosomal recessive lissencephaly with cerebellar hypoplasia is associated with human RELN mutations. Nat Genet 26:93-96.
7. Howell BW, Herrick TM, Hildebrand JD, Zhang Y, Cooper JA. (2000) Dab1 tyrosine phosphorylation sites relay positional signals during mouse brain development. Curr Biol 10:877-885. (Pubitemid 30647616)
8. Kakita A, Hayashi S, Moro F, Guerrini R, Ozawa T, Ono K, Kameyama S, Walsh CA, Takahashi H. (2002) Bilateral periventricular nodular heterotopia due to filamin 1 gene mutation: widespread glomeruloid microvascular anomaly and dysplastic cytoarchitecture in the cerebral cortex. Acta Neuropathol 104:649-657. (Pubitemid 36075430)
9. Kubo K, Honda T, Tomita K, Sekine K, Ishii K, Uto A, Kobayashi K, Tabata H, Nakajima K. (2010) Ectopic Reelin induces neuronal aggregation with a normal birthdate-dependent "inside-out" alignment in the developing neocortex. J Neurosci 30:10953-10966.
10. Marin-PadillaM, Marin-Padilla TM. (1982) Origin, prenatal development and structural organization of layer I of the human cerebral (motor) cortex. A Golgi study. Anat Embryol (Berl) 164:161-206.
11. Meroni A, Galli C, Bramerio M, Tassi L, Colombo N, Cossu M, Lo Russo G, Garbelli R, Spreafico R. (2009) Nodular heterotopia: a neuropathological study of 24 patients undergoing surgery for drug-resistant epilepsy. Epilepsia 50:116-124.
12. Rakic P. (2009) Evolution of the neocortex: a perspective from developmental biology. Nat Rev Neurosci 10:724-735.
13. Rice DS, Curran T. (1999) Mutant mice with scrambled brains: understanding the signaling pathways that control cell positioning in the CNS. Genes Dev 13:2758-2773.
14. Thom M, Martinian L, Parnavelas JG, Sisodiya SM. (2004) Distribution of cortical interneurons in grey matter heterotopia in patients with epilepsy. Epilepsia 45:916-923. (Pubitemid 39062813)