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Volumn 25, Issue 2, 2011, Pages 355-367

Prostate diseases - Role of sex steroids and their inhibitors

Author keywords

5 reductase; Androgen receptor; Benign prostate hyperplasia; DHT; Prostate; Prostate cancer; Steroid metabolism; Testosterone

Indexed keywords

ANDROGEN RECEPTOR; ANDROSTANOLONE; CHOLESTENONE 5ALPHA REDUCTASE; DUTASTERIDE; DUTASTERIDE PLUS TAMSULOSIN; FINASTERIDE; GONADORELIN AGONIST; GONADORELIN ANTAGONIST; PLACEBO; TAMSULOSIN; TESTOSTERONE;

EID: 79952550843     PISSN: 1521690X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.beem.2010.09.008     Document Type: Review
Times cited : (8)

References (114)
  • 1
    • 33645956542 scopus 로고    scopus 로고
    • BPH: Epidemiology and comorbidities
    • McVary KT. BPH: epidemiology and comorbidities. The American Journal of Managed Care 2006; 12(Suppl. 5): S122-S128.
    • (2006) The American Journal of Managed Care , vol.12 , Issue.SUPPL. 5
    • McVary, K.T.1
  • 3
    • 16244403039 scopus 로고    scopus 로고
    • Cancer incidence and mortality in Europe, 2004
    • Boyle P & Ferlay J. Cancer incidence and mortality in Europe, 2004. Annals of Oncology 2005; 16(3): 481-488.
    • Annals of Oncology 2005 , vol.16 , Issue.3 , pp. 481-488
    • Boyle, P.1    Ferlay, J.2
  • 4
    • 0027937517 scopus 로고
    • High grade prostatic intraepithelial neoplasia (HGPIN) and prostatic adenocarcinoma between the ages of 20-69: An autopsy study of 249 cases
    • Sakr WA, Grignon DJ, Crissman JD et al. High grade prostatic intraepithelial neoplasia (HGPIN) and prostatic adenocarcinoma between the ages of 20-69: an autopsy study of 249 cases. In Vivo 1994; 8(3): 439-443.
    • (1994) In Vivo , vol.8 , Issue.3 , pp. 439-443
    • Sakr, W.A.1    Grignon, D.J.2    Crissman, J.D.3
  • 6
    • 43449127502 scopus 로고    scopus 로고
    • Prostate cancer
    • *6. Damber JE & Aus G. Prostate cancer. Lancet 2008; 371(9625): 1710-1721.
    • (2008) Lancet , vol.371 , Issue.9625 , pp. 1710-1721
    • Damber, J.E.1    Aus, G.2
  • 7
    • 0026065033 scopus 로고
    • Immunohistochemical and in-situ hybridization analysis of androgen receptor expression during the development of the mouse prostate gland
    • Takeda H & Chang C. Immunohistochemical and in-situ hybridization analysis of androgen receptor expression during the development of the mouse prostate gland. The Journal of Endocrinology 1991; 129(1): 83-89.
    • (1991) The Journal of Endocrinology , vol.129 , Issue.1 , pp. 83-89
    • Takeda, H.1    Chang, C.2
  • 8
    • 0025743234 scopus 로고
    • Androgen receptor expression in developing male reproductive organs
    • Cooke PS, Young P & Cunha GR. Androgen receptor expression in developing male reproductive organs. Endocrinology 1991; 128(6): 2867-2873.
    • (1991) Endocrinology , vol.128 , Issue.6 , pp. 2867-2873
    • Cooke, P.S.1    Young, P.2    Cunha, G.R.3
  • 9
    • 65549123952 scopus 로고    scopus 로고
    • Low stroma androgen receptor level in normal and tumour prostate tissue is related to poor outcome in prostate cancer patients
    • Wikstrom P, Marusic J, Stattin P et al. Low stroma androgen receptor level in normal and tumour prostate tissue is related to poor outcome in prostate cancer patients. The Prostate 2009; 69(8): 799-809.
    • (2009) The Prostate , vol.69 , Issue.8 , pp. 799-809
    • Wikstrom, P.1    Marusic, J.2    Stattin, P.3
  • 10
    • 0025751540 scopus 로고
    • Androgen receptor localization in different cell types of the adult rat prostate
    • Prins GS, Birch L & Greene GL. Androgen receptor localization in different cell types of the adult rat prostate. Endocrinology 1991; 129(6): 3187-3199.
    • (1991) Endocrinology , vol.129 , Issue.6 , pp. 3187-3199
    • Prins, G.S.1    Birch, L.2    Greene, G.L.3
  • 11
    • 44249112547 scopus 로고    scopus 로고
    • Androgen receptor is causally involved in the homeostasis of the human prostate endothelial cell
    • DOI 10.1210/en.2007-1078
    • Godoy A, Watts A, Sotomayor P et al. Androgen receptor is causally involved in the homeostasis of the human prostate endothelial cell. Endocrinology 2008; 149(6): 2959-2969. (Pubitemid 351724500)
    • (2008) Endocrinology , vol.149 , Issue.6 , pp. 2959-2969
    • Godoy, A.1    Watts, A.2    Sotomayor, P.3    Montecinos, V.P.4    Huss, W.J.5    Onate, S.A.6    Smith, G.J.7
  • 12
    • 0042415425 scopus 로고    scopus 로고
    • Role of the stromal microenvironment in carcinogenesis of the prostate
    • Cunha GR, Hayward SW, Wang YZ et al. Role of the stromal microenvironment in carcinogenesis of the prostate. International Journal of Cancer 2003; 107(1): 1-10.
    • (2003) International Journal of Cancer , vol.107 , Issue.1 , pp. 1-10
    • Cunha, G.R.1    Hayward, S.W.2    Wang, Y.Z.3
  • 13
    • 0028366004 scopus 로고
    • Androgen receptor immunostaining and its tissue distribution in formalin- Fixed, paraffin-embedded sections after microwave treatment
    • Iwamura M, Abrahamsson PA, Benning CM et al. Androgen receptor immunostaining and its tissue distribution in formalin-fixed, paraffin-embedded sections after microwave treatment. The Journal of Histochemistry and Cytochemistry 1994; 42(6): 783-788. (Pubitemid 24159889)
    • (1994) Journal of Histochemistry and Cytochemistry , vol.42 , Issue.6 , pp. 783-788
    • Iwamura, M.1    Abrahamsson, P.-A.2    Benning, C.M.3    Cockett, A.T.K.4    Di, S.'.P.A.5
  • 14
    • 0027418018 scopus 로고
    • Immunocytochemical localization of androgen receptor with polyclonal antibody in paraffin-embedded human tissues
    • Kimura N, Mizokami A, Oonuma T et al. Immunocytochemical localization of androgen receptor with polyclonal antibody in paraffin-embedded human tissues. The Journal of Histochemistry and Cytochemistry 1993; 41(5): 671-678. (Pubitemid 23118737)
    • (1993) Journal of Histochemistry and Cytochemistry , vol.41 , Issue.5 , pp. 671-678
    • Kimura, N.1    Mizokami, A.2    Oonuma, T.3    Sasano, H.4    Nagura, H.5
  • 15
    • 0023501125 scopus 로고
    • Response of glandular versus basal rat ventral prostatic epithelial cells to androgen withdrawal and replacement
    • DOI 10.1002/pros.2990110304
    • English HF, Santen RJ & Isaacs JT. Response of glandular versus basal rat ventral prostatic epithelial cells to androgen withdrawal and replacement. The Prostate 1987; 11(3): 229-242. (Pubitemid 18004762)
    • (1987) Prostate , vol.11 , Issue.3 , pp. 229-242
    • English, H.F.1    Santen, R.J.2    Isaacs, J.T.3
  • 16
    • 0027438929 scopus 로고
    • Androgen receptor status in endocrine-paracrine cell types of the normal, hyperplastic, and neoplastic human prostate
    • Bonkhoff H, Stein U & Remberger K. Androgen receptor status in endocrine-paracrine cell types of the normal, hyperplastic, and neoplastic human prostate. Virchows Archiv. A, Pathological Anatomy and Histopathology 1993; 423(4): 291-294.
    • (1993) Virchows Archiv. A, Pathological Anatomy and Histopathology , vol.423 , Issue.4 , pp. 291-294
    • Bonkhoff, H.1    Stein, U.2    Remberger, K.3
  • 17
    • 0033305674 scopus 로고    scopus 로고
    • Androgen-induced regrowth in the castrated rat ventral prostate: Role of 5alpha-reductase
    • Wright AS, Douglas RC, Thomas LN et al. Androgen-induced regrowth in the castrated rat ventral prostate: role of 5alpha-reductase. Endocrinology 1999; 140(10): 4509-4515. (Pubitemid 30666115)
    • (1999) Endocrinology , vol.140 , Issue.10 , pp. 4509-4515
    • Wright, A.S.1    Douglas, R.C.2    Thomas, L.N.3    Lazier, C.B.4    Rittmaster, R.S.5
  • 18
    • 0026782628 scopus 로고
    • Testosterone and 5 alpha-dihydrotestosterone interact differently with the androgen receptor to enhance transcription of the MMTV-CAT reporter gene
    • Deslypere JP, Young M, Wilson JD et al. Testosterone and 5 alpha-dihydrotestosterone interact differently with the androgen receptor to enhance transcription of the MMTV-CAT reporter gene. Molecular and Cellular Endocrinology 1992; 88(1-3): 15-22.
    • (1992) Molecular and Cellular Endocrinology , vol.88 , Issue.1-3 , pp. 15-22
    • Deslypere, J.P.1    Young, M.2    Wilson, J.D.3
  • 19
    • 49249119358 scopus 로고    scopus 로고
    • Maintenance of intratumoral androgens in metastatic prostate cancer: A mechanism for castration-resistant tumour growth
    • Montgomery RB, Mostaghel EA, Vessella R et al. Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumour growth. Cancer Research 2008; 68(11): 4447-4454.
    • (2008) Cancer Research , vol.68 , Issue.11 , pp. 4447-4454
    • Montgomery, R.B.1    Mostaghel, E.A.2    Vessella, R.3
  • 20
    • 0032322998 scopus 로고    scopus 로고
    • Localization by in situ hybridization of steroid 5alpha- Reductase isozyme gene expression in the human prostate and preputial skin
    • DOI 10.1016/S0022-5347(01)62961-6
    • Pelletier G, Luu-The V, Huang XF et al. Localization by in situ hybridization of steroid 5alpha-reductase isozyme gene expression in the human prostate and preputial skin. The Journal of Urology 1998; 160(2): 577-582. (Pubitemid 29476737)
    • (1998) Journal of Urology , vol.160 , Issue.2 , pp. 577-582
    • Pelletier, G.1    Luu-The, V.2    Huang, X.-F.3    Lapointe, H.4    Labrie, F.5
  • 22
    • 36949000088 scopus 로고    scopus 로고
    • Novel 5alpha-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer
    • DOI 10.1111/j.1349-7006.2007.00656.x
    • Uemura M, Tamura K, Chung S et al. Novel 5 alpha-steroid reductase (SRD5A3, type-3) is overexpressed in hormonerefractory prostate cancer. Cancer Science 2008; 99(1): 81-86. (Pubitemid 350239034)
    • (2008) Cancer Science , vol.99 , Issue.1 , pp. 81-86
    • Uemura, M.1    Tamura, K.2    Chung, S.3    Honma, S.4    Okuyama, A.5    Nakamura, Y.6    Nakagawa, H.7
  • 24
    • 70350437986 scopus 로고    scopus 로고
    • The expression of androgen-responsive genes is up-regulated in the epithelia of benign prostatic hyperplasia
    • O'Malley KJ, Dhir R, Nelson JB et al. The expression of androgen-responsive genes is up-regulated in the epithelia of benign prostatic hyperplasia. The Prostate 2009; 69(16): 1716-1723.
    • (2009) The Prostate , vol.69 , Issue.16 , pp. 1716-1723
    • O'Malley, K.J.1    Dhir, R.2    Nelson, J.B.3
  • 25
    • 33751509661 scopus 로고    scopus 로고
    • Transcript profiling of the androgen signal in normal prostate, benign prostatic hyperplasia, and prostate cancer
    • DOI 10.1210/en.2006-0627
    • Bauman DR, Steckelbroeck S, Peehl DM et al. Transcript profiling of the androgen signal in normal prostate, benign prostatic hyperplasia, and prostate cancer. Endocrinology 2006; 147(12): 5806-5816. (Pubitemid 44833497)
    • (2006) Endocrinology , vol.147 , Issue.12 , pp. 5806-5816
    • Bauman, D.R.1    Steckelbroeck, S.2    Peehl, D.M.3    Penning, T.M.4
  • 26
    • 0023245164 scopus 로고
    • Effects of castration compared with total androgen blockade on tissue dihydrotestosterone (DHT) concentration in benign prostatic hyperplasia (BPH)
    • Geller J & Albert J. Effects of castration compared with total androgen blockade on tissue dihydrotestosterone (DHT) concentration in benign prostatic hyperplasia (BPH). Urological Research 1987; 15(3): 151-153.
    • (1987) Urological Research , vol.15 , Issue.3 , pp. 151-153
    • Geller, J.1    Albert, J.2
  • 27
    • 0037377691 scopus 로고    scopus 로고
    • The role of dihydrotestosterone in benign prostatic hyperplasia
    • DOI 10.1016/S0090-4295(03)00045-1
    • Carson 3rd C & Rittmaster R. The role of dihydrotestosterone in benign prostatic hyperplasia. Urology 2003; 61(4 Suppl.1): 2-7. (Pubitemid 36349123)
    • (2003) Urology , vol.61 , Issue.4 SUPPL. 1 , pp. 2-7
    • Carson III, C.1    Rittmaster, R.2
  • 30
    • 0347882750 scopus 로고    scopus 로고
    • The long-term effect of doxazosin, finasteride, and combination therapy on the clinical progression of benign prostatic hyperplasia
    • McConnell JD, Roehrborn CG, Bautista OM et al. The long-term effect of doxazosin, finasteride, and combination therapy on the clinical progression of benign prostatic hyperplasia. The New England Journal of Medicine 2003; 349(25): 2387-2398.
    • (2003) The New England Journal of Medicine , vol.349 , Issue.25 , pp. 2387-2398
    • McConnell, J.D.1    Roehrborn, C.G.2    Bautista, O.M.3
  • 31
    • 70449536472 scopus 로고    scopus 로고
    • The effects of combination therapy with dutasteride and tamsulosin on clinical outcomes in men with symptomatic benign prostatic hyperplasia: 4-year results from the CombAT study
    • Roehrborn CG, Siami P, Barkin J et al. The effects of combination therapy with dutasteride and tamsulosin on clinical outcomes in men with symptomatic benign prostatic hyperplasia: 4-year results from the CombAT study. European Urology 2010; 57(1): 123-131.
    • (2010) European Urology , vol.57 , Issue.1 , pp. 123-131
    • Roehrborn, C.G.1    Siami, P.2    Barkin, J.3
  • 32
    • 0036754256 scopus 로고    scopus 로고
    • Efficacy and safety of a dual inhibitor of 5-alpha-reductase types 1 and 2 (dutasteride) in men with benign prostatic hyperplasia
    • DOI 10.1016/S0090-4295(02)01905-2, PII S0090429502019052
    • Roehrborn CG, Boyle P, Nickel JC et al. Efficacy and safety of a dual inhibitor of 5-alpha-reductase types 1 and 2 (dutasteride) in men with benign prostatic hyperplasia. Urology 2002; 60(3): 434-441. (Pubitemid 35292169)
    • (2002) Urology , vol.60 , Issue.3 , pp. 434-441
    • Roehrborn, C.G.1    Boyle, P.2    Nickel, J.C.3    Hoefner, K.4    Andriole, G.5
  • 33
    • 27144558258 scopus 로고    scopus 로고
    • Endocrine therapy for prostate cancer
    • Damber JE. Endocrine therapy for prostate cancer. Acta Oncologica 2005; 44(6): 605-609.
    • (2005) Acta Oncologica , vol.44 , Issue.6 , pp. 605-609
    • Damber, J.E.1
  • 34
    • 56649116179 scopus 로고    scopus 로고
    • The efficacy and safety of degarelix: A 12-month, comparative, randomized, open-label, parallel-group phase III study in patients with prostate cancer
    • Klotz L, Boccon-Gibod L, Shore ND et al. The efficacy and safety of degarelix: a 12-month, comparative, randomized, open-label, parallel-group phase III study in patients with prostate cancer. BJU International 2008; 102(11): 1531-1538.
    • (2008) BJU International , vol.102 , Issue.11 , pp. 1531-1538
    • Klotz, L.1    Boccon-Gibod, L.2    Shore, N.D.3
  • 35
    • 0037099723 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of monotherapy compared with combined androgen blockade for patients with advanced prostate carcinoma
    • Samson DJ, Seidenfeld J, Schmitt B et al. Systematic review and meta-analysis of monotherapy compared with combined androgen blockade for patients with advanced prostate carcinoma. Cancer 2002; 95(2): 361-376.
    • (2002) Cancer , vol.95 , Issue.2 , pp. 361-376
    • Samson, D.J.1    Seidenfeld, J.2    Schmitt, B.3
  • 37
    • 70449523110 scopus 로고    scopus 로고
    • Potential benefits of intermittent androgen suppression therapy in the treatment of prostate cancer: A systematic review of the literature
    • Abrahamsson PA. Potential benefits of intermittent androgen suppression therapy in the treatment of prostate cancer: a systematic review of the literature. European Urology 2010; 57(1): 49-59.
    • (2010) European Urology , vol.57 , Issue.1 , pp. 49-59
    • Abrahamsson, P.A.1
  • 38
    • 1042269786 scopus 로고
    • Effect of orchidectomy and irradiation on cancer of the prostate
    • Huggins C. Effect of orchidectomy and irradiation on cancer of the prostate. Annals of Surgery 1942; 115(6): 1192-1200.
    • (1942) Annals of Surgery , vol.115 , Issue.6 , pp. 1192-1200
    • Huggins, C.1
  • 39
    • 84928580276 scopus 로고
    • Studies on prostate cancer. 1 the effect of castration, of estrogens and of androgen injection on serum phosphatase in metastatic carcinoma of the prostate
    • Huggins CH & Hodges CV. Studies on prostate cancer. 1 The effect of castration, of estrogens and of androgen injection on serum phosphatase in metastatic carcinoma of the prostate. Cancer Research 1941; 1: 293-297.
    • (1941) Cancer Research , vol.1 , pp. 293-297
    • Huggins, C.H.1    Hodges, C.V.2
  • 40
    • 72049107165 scopus 로고    scopus 로고
    • A holistic approach to androgen deprivation therapy: Treating the cancer without hurting the patient
    • Tombal B. A holistic approach to androgen deprivation therapy: treating the cancer without hurting the patient. Urologia Internationalis 2009; 83(4): 373-378.
    • (2009) Urologia Internationalis , vol.83 , Issue.4 , pp. 373-378
    • Tombal, B.1
  • 41
    • 17644362707 scopus 로고    scopus 로고
    • Differential alterations in 5alpha-reductase type 1 and type 2 levels during development and progression of prostate cancer
    • DOI 10.1002/pros.20188
    • Thomas LN, Lazier CB, Gupta R et al. Differential alterations in 5alpha-reductase type 1 and type 2 levels during development and progression of prostate cancer. The Prostate 2005; 63(3): 231-239. (Pubitemid 40571057)
    • (2005) Prostate , vol.63 , Issue.3 , pp. 231-239
    • Thomas, L.N.1    Lazier, C.B.2    Gupta, R.3    Norman, R.W.4    Troyer, D.A.5    O'Brien, S.P.6    Rittmaster, R.S.7
  • 43
    • 20444435607 scopus 로고    scopus 로고
    • Relationship between changes in prostate cancer cell proliferation, apoptotic index, and expression of apoptosis-related proteins by neoadjuvant hormonal therapy and duration of such treatment
    • DOI 10.1016/j.urology.2005.01.028, PII S0090429505001007
    • Miyata Y, Kanda S, Sakai H et al. Relationship between changes in prostate cancer cell proliferation, apoptotic index, and expression of apoptosis-related proteins by neoadjuvant hormonal therapy and duration of such treatment. Urology 2005; 65(6): 1238-1243. (Pubitemid 40824938)
    • (2005) Urology , vol.65 , Issue.6 , pp. 1238-1243
    • Miyata, Y.1    Kanda, S.2    Sakai, H.3    Hakariya, T.4    Kanetake, H.5
  • 44
    • 0028843851 scopus 로고
    • Treatment with finasteride following radical prostatectomy for prostate cancer
    • Andriole G, Lieber M, Smith J et al. Treatment with finasteride following radical prostatectomy for prostate cancer. Urology 1995; 45(3): 491-497.
    • (1995) Urology , vol.45 , Issue.3 , pp. 491-497
    • Andriole, G.1    Lieber, M.2    Smith, J.3
  • 45
    • 0028799960 scopus 로고
    • Combination finasteride and flutamide in advanced carcinoma of the prostate: Effective therapy with minimal side effects
    • discussion 1645-6
    • Fleshner NE & Trachtenberg J. Combination finasteride and flutamide in advanced carcinoma of the prostate: effective therapy with minimal side effects. The Journal of Urology 1995; 154(5): 1642-1645 [discussion 1645-6].
    • (1995) The Journal of Urology , vol.154 , Issue.5 , pp. 1642-1645
    • Fleshner, N.E.1    Trachtenberg, J.2
  • 46
    • 0031010962 scopus 로고    scopus 로고
    • Finasteride and flutamide as potency-sparing androgen-ablative therapy for advanced adenocarcinoma of the prostate
    • DOI 10.1016/S0090-4295(97)00091-5, PII S0090429597000915
    • Brufsky A, Fontaine-Rothe P, Berlane K et al. Finasteride and flutamide as potency-sparing androgen-ablative therapy for advanced adenocarcinoma of the prostate. Urology 1997; 49(6): 913-920. (Pubitemid 27246962)
    • (1997) Urology , vol.49 , Issue.6 , pp. 913-920
    • Brufsky, A.1    Fontaine-Rothe, P.2    Berlane, K.3    Rieker, P.4    Jiroutek, M.5    Kaplan, I.6    Kaufman, D.7    Kantoff, P.8
  • 47
    • 0030468455 scopus 로고    scopus 로고
    • Combined finasteride and flutamide therapy in men with advanced prostate cancer
    • DOI 10.1016/S0090-4295(96)00315-9, PII S0090429596003159
    • Ornstein DK, Rao GS, Johnson B et al. Combined finasteride and flutamide therapy in men with advanced prostate cancer. Urology 1996; 48(6): 901-905. (Pubitemid 26427098)
    • (1996) Urology , vol.48 , Issue.6 , pp. 901-905
    • Ornstein, D.K.1    Rao, G.S.2    Johnson, B.3    Charlton, E.T.4    Andriole, G.L.5
  • 49
    • 0242495783 scopus 로고    scopus 로고
    • Combination of low-dose flutamide and finasteride for PSA-only recurrent prostate cancer after primary therapy
    • DOI 10.1016/S0090-4295(03)00667-8
    • Barqawi AB, Moul JW, Ziada A et al. Combination of low-dose flutamide and finasteride for PSA-only recurrent prostate cancer after primary therapy. Urology 2003; 62(5): 872-876. (Pubitemid 37421234)
    • (2003) Urology , vol.62 , Issue.5 , pp. 872-876
    • Barqawi, A.B.1    Moul, J.W.2    Ziada, A.3    Handel, L.4    Crawford, E.D.5
  • 50
    • 0033045720 scopus 로고    scopus 로고
    • Finasteride in association with either flutamide or goserelin as combination hormonal therapy in patients with stage M1 carcinoma of the prostate gland
    • DOI 10.1002/(SICI)1097-0045(19990701)40:2<105::AID-PROS6>3.0.CO;2-9
    • Kirby R, Robertson C, Turkes A et al. Finasteride in association with either flutamide or goserelin as combination hormonal therapy in patients with stage M1 carcinoma of the prostate gland. International prostate health council (IPHC) trial study group. The Prostate 1999; 40(2): 105-114. (Pubitemid 29304701)
    • (1999) Prostate , vol.40 , Issue.2 , pp. 105-114
    • Kirby, R.1    Robertson, C.2    Turkes, A.3    Griffiths, K.4    Denis, L.J.5    Boyle, P.6    Altwein, J.7    Schroder, F.8
  • 51
    • 0034811710 scopus 로고    scopus 로고
    • Hormones and prostate cancer: What's next?
    • Hsing AW. Hormones and prostate cancer: what's next? Epidemiologic Reviews 2001; 23(1): 42-58.
    • (2001) Epidemiologic Reviews , vol.23 , Issue.1 , pp. 42-58
    • Hsing, A.W.1
  • 52
    • 12344275741 scopus 로고    scopus 로고
    • The epidemiology of sex steroid hormones and their signaling and metabolic pathways in the etiology of prostate cancer
    • DOI 10.1016/j.jsbmb.2004.10.002, PII S0960076004003644, Steroids and Prostate Cancer
    • Platz EA & Giovannucci E. The epidemiology of sex steroid hormones and their signaling and metabolic pathways in the etiology of prostate cancer. The Journal of Steroid Biochemistry and Molecular Biology 2004; 92(4): 237-253. (Pubitemid 40128245)
    • (2004) Journal of Steroid Biochemistry and Molecular Biology , vol.92 , Issue.4 , pp. 237-253
    • Platz, E.A.1    Giovannucci, E.2
  • 53
    • 39149084101 scopus 로고    scopus 로고
    • Endogenous sex hormones and prostate cancer: A collaborative analysis of 18 prospective studies
    • Roddam AW, Allen NE, Appleby P et al. Endogenous sex hormones and prostate cancer: a collaborative analysis of 18 prospective studies. Journal of the National Cancer Institute 2008; 100(3): 170-183.
    • (2008) Journal of the National Cancer Institute , vol.100 , Issue.3 , pp. 170-183
    • Roddam, A.W.1    Allen, N.E.2    Appleby, P.3
  • 54
    • 77956596257 scopus 로고    scopus 로고
    • A large study of androgen receptor germline variants and their relation to sex hormone levels and prostate cancer risk. Results from the national cancer institute breast and prostate cancer cohort consortium
    • Lindstrom S, Ma J, Altshuler D et al. A large study of androgen receptor germline variants and their relation to sex hormone levels and prostate cancer risk. Results from the national cancer institute breast and prostate cancer cohort consortium. The Journal of Clinical Endocrinology and Metabolism 2010.
    • (2010) The Journal of Clinical Endocrinology and Metabolism
    • Lindstrom, S.1    Ma, J.2    Altshuler, D.3
  • 55
    • 59249083522 scopus 로고    scopus 로고
    • Does testosterone therapy increase the risk of prostate cancer?
    • Dobs AS & Morgentaler A. Does testosterone therapy increase the risk of prostate cancer? Endocrine Practice 2008; 14 (7): 904-911.
    • (2008) Endocrine Practice , vol.14 , Issue.7 , pp. 904-911
    • Dobs, A.S.1    Morgentaler, A.2
  • 56
    • 59349086267 scopus 로고    scopus 로고
    • Testosterone therapy in men with prostate cancer: Scientific and ethical considerations
    • Morgentaler A. Testosterone therapy in men with prostate cancer: scientific and ethical considerations. The Journal of Urology 2009; 181(3): 972-979.
    • (2009) The Journal of Urology , vol.181 , Issue.3 , pp. 972-979
    • Morgentaler, A.1
  • 57
    • 0037203519 scopus 로고    scopus 로고
    • Androgens and male physiology the syndrome of 5alpha-reductase-2 deficiency
    • DOI 10.1016/S0303-7207(02)00368-4, PII S0303720702003684
    • Imperato-McGinley J & Zhu YS. Androgens and male physiology the syndrome of 5alpha-reductase-2 deficiency. Molecular and Cellular Endocrinology 2002; 198(1-2): 51-59. (Pubitemid 36169934)
    • (2002) Molecular and Cellular Endocrinology , vol.198 , Issue.1-2 , pp. 51-59
    • Imperato-McGinley, J.1    Zhu, Y.-S.2
  • 58
    • 40849135468 scopus 로고    scopus 로고
    • The rationale for inhibiting 5alpha-reductase isoenzymes in the prevention and treatment of prostate cancer
    • Tindall DJ & Rittmaster RS. The rationale for inhibiting 5alpha-reductase isoenzymes in the prevention and treatment of prostate cancer. The Journal of Urology 2008; 179(4): 1235-1242.
    • (2008) The Journal of Urology , vol.179 , Issue.4 , pp. 1235-1242
    • Tindall, D.J.1    Rittmaster, R.S.2
  • 60
    • 27744492261 scopus 로고    scopus 로고
    • The effects of 5alpha-reductase inhibitors on the natural history, detection and grading of prostate cancer: Current state of knowledge
    • DOI 10.1097/01.ju.0000181216.71605.38
    • Andriole G, Bostwick D, Civantos F et al. The effects of 5alpha-reductase inhibitors on the natural history, detection and grading of prostate cancer: current state of knowledge. The Journal of Urology 2005; 174(6): 2098-2104. (Pubitemid 41611745)
    • (2005) Journal of Urology , vol.174 , Issue.6 , pp. 2098-2104
    • Andriole, G.1    Bostwick, D.2    Civantos, F.3    Epstein, J.4    Lucia, M.S.5    McConnell, J.6    Roehrborn, C.G.7
  • 61
    • 34548217770 scopus 로고    scopus 로고
    • Low-activity V89L variant in SRD5A2 is associated with aggressive prostate cancer risk: An explanation for the adverse effects observed in chemoprevention trials using 5-alpha-reductase inhibitors
    • Cussenot O, Azzouzi AR, Nicoliew N et al. Low-activity V89L variant in SRD5A2 is associated with aggressive prostate cancer risk: an explanation for the adverse effects observed in chemoprevention trials using 5-alpha-reductase inhibitors. European Urology 2007; 52(4): 1082-1087.
    • (2007) European Urology , vol.52 , Issue.4 , pp. 1082-1087
    • Cussenot, O.1    Azzouzi, A.R.2    Nicoliew, N.3
  • 63
    • 76249096762 scopus 로고    scopus 로고
    • Evidence of limited contributions for intratumoral steroidogenesis in prostate cancer
    • Hofland J, van Weerden WM, Dits NF et al. Evidence of limited contributions for intratumoral steroidogenesis in prostate cancer. Cancer Research 2010; 70(3): 1256-1264.
    • (2010) Cancer Research , vol.70 , Issue.3 , pp. 1256-1264
    • Hofland, J.1    Van Weerden, W.M.2    Dits, N.F.3
  • 64
    • 76749096777 scopus 로고    scopus 로고
    • Variability in the androgen response of prostate epithelium to 5alpha-reductase inhibition: Implications for prostate cancer chemoprevention
    • Mostaghel EA, Geng L, Holcomb I et al. Variability in the androgen response of prostate epithelium to 5alpha-reductase inhibition: implications for prostate cancer chemoprevention. Cancer Research 2010; 70(4): 1286-1295.
    • (2010) Cancer Research , vol.70 , Issue.4 , pp. 1286-1295
    • Mostaghel, E.A.1    Geng, L.2    Holcomb, I.3
  • 65
    • 0020677188 scopus 로고
    • Hormone-induced morphogenesis and growth: Role of mesenchymal-epithelial interactions
    • Cunha GR, Chung LW, Shannon JM et al. Hormone-induced morphogenesis and growth: role of mesenchymal-epithelial interactions. Recent Progress in Hormone Research 1983; 39: 559-598.
    • (1983) Recent Progress in Hormone Research , vol.39 , pp. 559-598
    • Cunha, G.R.1    Chung, L.W.2    Shannon, J.M.3
  • 67
    • 0031732855 scopus 로고    scopus 로고
    • Testosterone stimulates angiogenesis and vascular regrowth in the ventral prostate in castrated adult rats
    • DOI 10.1210/en.139.2.451
    • Franck-Lissbrant I, Haggstrom S, Damber JE et al. Testosterone stimulates angiogenesis and vascular regrowth in the ventral prostate in castrated adult rats. Endocrinology 1998; 139(2): 451-456. (Pubitemid 28513188)
    • (1998) Endocrinology , vol.139 , Issue.2 , pp. 451-456
    • Franck-Lissbrant, I.1    Haggstrom, S.2    Damber, J.-E.3    Bergh, A.4
  • 69
    • 0035176826 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression and tumor angiogenesis are regulated by androgens in hormone responsive human prostate carcinoma: Evidence for androgen dependent destabilization of vascular endothelial growth factor transcripts
    • DOI 10.1097/00005392-200102000-00095
    • Stewart RJ, Panigrahy RJ, Flynn E et al. Vascular endothelial growth factor expression and tumour angiogenesis are regulated by androgens in hormone responsive human prostate carcinoma: evidence for androgen dependent destabilization of vascular endothelial growth factor transcripts. The Journal of Urology 2001; 165(2): 688-693. (Pubitemid 32060501)
    • (2001) Journal of Urology , vol.165 , Issue.2 , pp. 688-693
    • Stewart, R.J.1    Panigrahy, D.2    Flynn, E.3    Folkman, J.4
  • 70
    • 33847378858 scopus 로고    scopus 로고
    • Androgen-insensitive prostate cancer cells transiently respond to castration treatment when growing in an androgen-dependent prostate environment
    • DOI 10.1002/pros.20473
    • Halin S, Hammarsten P, Wikstrom P et al. Androgen-insensitive prostate cancer cells transiently respond to castration treatment when growing in an androgen-dependent prostate environment. The Prostate 2007; 67(4): 370-377. (Pubitemid 46341077)
    • (2007) Prostate , vol.67 , Issue.4 , pp. 370-377
    • Halin, S.1    Hammarsten, P.2    Wikstrom, P.3    Bergh, A.4
  • 71
    • 34547169546 scopus 로고    scopus 로고
    • Cellular Changes in Prostate Cancer Cells Induced by Intermittent Androgen Suppression
    • DOI 10.1016/j.eururo.2006.11.043, PII S030228380601476X
    • Laitinen S, Martikainen PM, Tammela TL et al. Cellular changes in prostate cancer cells induced by intermittent androgen suppression. European Urology 2007; 52(3): 725-732. (Pubitemid 47126127)
    • (2007) European Urology , vol.52 , Issue.3 , pp. 725-732
    • Laitinen, S.1    Martikainen, P.M.2    Tammela, T.L.J.3    Visakorpi, T.4
  • 72
    • 13544277666 scopus 로고    scopus 로고
    • Cell proliferation and apoptosis in prostate tumors and adjacent non-malignant prostate tissue in patients at different time-points after castration treatment
    • DOI 10.1002/pros.20139
    • Ohlson N, Wikstrom P, Stattin P et al. Cell proliferation and apoptosis in prostate tumors and adjacent non-malignant prostate tissue in patients at different time-points after castration treatment. The Prostate 2005; 62(4): 307-315. (Pubitemid 40224136)
    • (2005) Prostate , vol.62 , Issue.4 , pp. 307-315
    • Ohlson, N.1    Wikstrom, P.2    Stattin, P.3    Bergh, A.4
  • 73
    • 0029060164 scopus 로고
    • Castration therapy rapidly induces apoptosis in a minority and decreases cell proliferation in a majority of human prostatic tumors
    • Westin P, Stattin P, Damber JE et al. Castration therapy rapidly induces apoptosis in a minority and decreases cell proliferation in a majority of human prostatic tumors. The American Journal of Pathology 1995; 146(6): 1368-1375.
    • (1995) The American Journal of Pathology , vol.146 , Issue.6 , pp. 1368-1375
    • Westin, P.1    Stattin, P.2    Damber, J.E.3
  • 74
    • 0033104627 scopus 로고    scopus 로고
    • Early castration-induced upregulation of transforming growth factor beta1 and its receptors is associated with tumor cell apoptosis and a major decline in serum prostate-specific antigen in prostate cancer patients
    • Wikstrom P,Westin P, Stattin P et al. Early castration-induced up regulation of transforming growth factor beta1 and its receptors is associated with tumour cell apoptosis and a major decline in serum prostate-specific antigen in prostate cancer patients. The Prostate 1999; 38(4): 268-277. (Pubitemid 29119792)
    • (1999) Prostate , vol.38 , Issue.4 , pp. 268-277
    • Wikstrom, P.1    Westin, P.2    Stattin, P.3    Damber, J.-E.4    Bergh, A.5
  • 75
    • 13644262076 scopus 로고    scopus 로고
    • Transition of an androgen-dependent human prostate cancer cell line into an androgen-independent subline is associated with increased angiogenesis
    • DOI 10.1002/pros.20145
    • Gustavsson H, Welen K & Damber JE. Transition of an androgen-dependent human prostate cancer cell line into an androgen-independent subline is associated with increased angiogenesis. The Prostate 2005; 62(4): 364-373. (Pubitemid 40227488)
    • (2005) Prostate , vol.62 , Issue.4 , pp. 364-373
    • Gustavsson, H.1    Welen, K.2    Damber, J.-E.3
  • 77
    • 47849123300 scopus 로고    scopus 로고
    • Androgen inhibits the growth of carcinoma cell lines established from prostate cancer xenografts that escape androgen treatment
    • Joly-Pharaboz MO, Kalach JJ, Pharaboz J et al. Androgen inhibits the growth of carcinoma cell lines established from prostate cancer xenografts that escape androgen treatment. The Journal of Steroid Biochemistry and Molecular Biology 2008; 111(1-2): 50-59.
    • (2008) The Journal of Steroid Biochemistry and Molecular Biology , vol.111 , Issue.1-2 , pp. 50-59
    • Joly-Pharaboz, M.O.1    Kalach, J.J.2    Pharaboz, J.3
  • 79
    • 33845329200 scopus 로고    scopus 로고
    • Prevalence of prostate cancer among hypogonadal men with prostate-specific antigen levels of 4.0 ng/mL or less
    • DOI 10.1016/j.urology.2006.08.1058, PII S0090429506019625
    • Morgentaler A & Rhoden EL. Prevalence of prostate cancer among hypogonadal men with prostate-specific antigen levels of 4.0 ng/mL or less. Urology 2006; 68(6): 1263-1267. (Pubitemid 44880344)
    • (2006) Urology , vol.68 , Issue.6 , pp. 1263-1267
    • Morgentaler, A.1    Rhoden, E.L.2
  • 81
  • 82
    • 4043160542 scopus 로고    scopus 로고
    • Prevention of prostate cancer by androgens: Experimental paradox or clinical reality
    • discussion 294-5
    • Algarte-Genin M, Cussenot O & Costa P. Prevention of prostate cancer by androgens: experimental paradox or clinical reality. European Urology 2004; 46(3): 285-294 [discussion 294-5].
    • (2004) European Urology , vol.46 , Issue.3 , pp. 285-294
    • Algarte-Genin, M.1    Cussenot, O.2    Costa, P.3
  • 83
    • 0036843923 scopus 로고    scopus 로고
    • Association between prostate cancer and serum testosterone levels
    • DOI 10.1002/pros.10140
    • Zhang PL, Rosen S, Veeramachaneni R et al. Association between prostate cancer and serum testosterone levels. The Prostate 2002; 53(3): 179-182. (Pubitemid 35266177)
    • (2002) Prostate , vol.53 , Issue.3 , pp. 179-182
    • Zhang, P.L.1    Rosen, S.2    Veeramachaneni, R.3    Kao, J.4    DeWolf, W.C.5    Bubley, G.6
  • 85
    • 0032535307 scopus 로고    scopus 로고
    • Androgen receptor expression in androgen-independent prostate cancer is associated with increased expression of androgen-regulated genes
    • Gregory CW, Hamil KG, Kim D et al. Androgen receptor expression in androgen-independent prostate cancer is associated with increased expression of androgen-regulated genes. Cancer Research 1998; 58(24): 5718-5724. (Pubitemid 29006412)
    • (1998) Cancer Research , vol.58 , Issue.24 , pp. 5718-5724
    • Gregory, C.W.1    Hamil, K.G.2    Kim, D.3    Hall, S.H.4    Pretlow, T.G.5    Mohler, J.L.6    French, F.S.7
  • 86
    • 0028944138 scopus 로고
    • In vivo amplification of the androgen receptor gene and progression of human prostate cancer
    • Visakorpi T, Hyytinen E, Koivisto P et al. In vivo amplification of the androgen receptor gene and progression of human prostate cancer. Nature Genetics 1995; 9(4): 401-406.
    • (1995) Nature Genetics , vol.9 , Issue.4 , pp. 401-406
    • Visakorpi, T.1    Hyytinen, E.2    Koivisto, P.3
  • 88
    • 0029011116 scopus 로고
    • Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer
    • Taplin ME, Bubley GJ, Shuster TD et al. Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer. The New England Journal of Medicine 1995; 332(21): 1393-1398.
    • (1995) The New England Journal of Medicine , vol.332 , Issue.21 , pp. 1393-1398
    • Taplin, M.E.1    Bubley, G.J.2    Shuster, T.D.3
  • 89
    • 0035300409 scopus 로고    scopus 로고
    • Androgen receptor stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen
    • Gregory CW, Johnson Jr. RT, Mohler JL et al. Androgen receptor stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen. Cancer Research 2001; 61(7): 2892-2898. (Pubitemid 32691931)
    • (2001) Cancer Research , vol.61 , Issue.7 , pp. 2892-2898
    • Gregory, C.W.1    Johnson Jr., R.T.2    Mohler, J.L.3    French, F.S.4    Wilson, E.M.5
  • 90
  • 91
    • 27644452640 scopus 로고    scopus 로고
    • Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer
    • DOI 10.1158/1078-0432.CCR-05-0525
    • Titus MA, Schell MJ, Lih FB et al. Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer. Clinical Cancer Research 2005; 11(13): 4653-4657. (Pubitemid 41557182)
    • (2005) Clinical Cancer Research , vol.11 , Issue.13 , pp. 4653-4657
    • Titus, M.A.1    Schell, M.J.2    Lih, F.B.3    Tomer, K.B.4    Mohler, J.L.5
  • 93
    • 33645056171 scopus 로고    scopus 로고
    • Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer
    • Stanbrough M et al. Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer. Cancer Research 2006; 66(5): 2815-2825.
    • (2006) Cancer Research , vol.66 , Issue.5 , pp. 2815-2825
    • Stanbrough, M.1
  • 94
    • 77951523950 scopus 로고    scopus 로고
    • Phase I clinical trial of the CYP17 inhibitor abiraterone acetate demonstrating clinical activity in patients with castration-resistant prostate cancer who received prior ketoconazole therapy
    • Ryan CJ, SMith MR, Fong L et al. Phase I clinical trial of the CYP17 inhibitor abiraterone acetate demonstrating clinical activity in patients with castration-resistant prostate cancer who received prior ketoconazole therapy. Journal of Clinical Oncology 2010; 28(9): 1481-1488.
    • (2010) Journal of Clinical Oncology , vol.28 , Issue.9 , pp. 1481-1488
    • Ryan, C.J.1    SMith, M.R.2    Fong, L.3
  • 95
    • 77951591066 scopus 로고    scopus 로고
    • Phase II multicenter study of abiraterone acetate plus prednisone therapy in patients with docetaxel-treated castration-resistant prostate cancer
    • Danila DC, Morris MJ, de Bono JS et al. Phase II multicenter study of abiraterone acetate plus prednisone therapy in patients with docetaxel-treated castration-resistant prostate cancer. Journal of Clinical Oncology 2010; 28(9): 1496-1501.
    • (2010) Journal of Clinical Oncology , vol.28 , Issue.9 , pp. 1496-1501
    • Danila, D.C.1    Morris, M.J.2    De Bono, J.S.3
  • 96
    • 77951518711 scopus 로고    scopus 로고
    • Significant and sustained antitumor activity in post-docetaxel, castration-resistant prostate cancer with the CYP17 inhibitor abiraterone acetate
    • Reid AH, Attard G, Danila DC et al. Significant and sustained antitumor activity in post-docetaxel, castration-resistant prostate cancer with the CYP17 inhibitor abiraterone acetate. Journal of Clinical Oncology 2010; 28(9): 1489-1495.
    • (2010) Journal of Clinical Oncology , vol.28 , Issue.9 , pp. 1489-1495
    • Reid, A.H.1    Attard, G.2    Danila, D.C.3
  • 97
    • 0027487289 scopus 로고
    • Importance of continued testicular suppression in hormone-refractory prostate cancer
    • Taylor CD, Elson P & Trump DL. Importance of continued testicular suppression in hormone-refractory prostate cancer. Journal of Clinical Oncology 1993; 11(11): 2167-2172. (Pubitemid 23332253)
    • (1993) Journal of Clinical Oncology , vol.11 , Issue.11 , pp. 2167-2172
    • Taylor, C.D.1    Elson, P.2    Trump, D.L.3
  • 99
    • 37249030356 scopus 로고    scopus 로고
    • A switch from E-cadherin to N-cadherin expression indicates epithelial to mesenchymal transition and is of strong and independent importance for the progress of prostate cancer
    • DOI 10.1158/1078-0432.CCR-07-1263
    • Gravdal K, Halvorsen OJ, Haukaas SA et al. A switch from E-cadherin to N-cadherin expression indicates epithelial to mesenchymal transition and is of strong and independent importance for the progress of prostate cancer. Clinical Cancer Research 2007; 13(23): 7003-7011. (Pubitemid 350276881)
    • (2007) Clinical Cancer Research , vol.13 , Issue.23 , pp. 7003-7011
    • Gravdal, K.1    Halvorsen, O.J.2    Haukaas, S.A.3    Akslen, L.A.4
  • 100
    • 77953576511 scopus 로고    scopus 로고
    • N-cadherin increases after androgen deprivation and is associated with metastasis in prostate cancer
    • Jennbacken K, Tesan T, Wang W et al. N-cadherin increases after androgen deprivation and is associated with metastasis in prostate cancer. Endocrine-Related Cancer 2010; 17(2): 469-479.
    • (2010) Endocrine-Related Cancer , vol.17 , Issue.2 , pp. 469-479
    • Jennbacken, K.1    Tesan, T.2    Wang, W.3
  • 101
    • 35148893123 scopus 로고    scopus 로고
    • Roles for the stem cell-associated intermediate filament nestin in prostate cancer migration and metastasis
    • DOI 10.1158/0008-5472.CAN-07-0806
    • Kleeberger W, Bova GS, Nielsen ME et al. Roles for the stem cell associated intermediate filament Nestin in prostate cancer migration and metastasis. Cancer Research 2007; 67(19): 9199-9206. (Pubitemid 47535906)
    • (2007) Cancer Research , vol.67 , Issue.19 , pp. 9199-9206
    • Kleeberger, W.1    Bova, G.S.2    Nielsen, M.E.3    Herawi, M.4    Chuang, A.-Y.5    Epstein, J.I.6    Berman, D.M.7
  • 102
    • 24044492845 scopus 로고    scopus 로고
    • Inhibition of the Akt, cyclooxygenase-2, and matrix metalloproteinase-9 pathways in combination with androgen deprivation therapy: Potential therapeutic approaches for prostate cancer
    • DOI 10.1002/mc.20121
    • Miyamoto H, Altuwaijri S, Cai Y et al. Inhibition of the Akt, cyclooxygenase-2, and matrix metalloproteinase-9 pathways in combination with androgen deprivation therapy: potential therapeutic approaches for prostate cancer. Molecular Carcinogenesis 2005; 44(1): 1-10. (Pubitemid 41216402)
    • (2005) Molecular Carcinogenesis , vol.44 , Issue.1 , pp. 1-10
    • Miyamoto, H.1    Altuwaijri, S.2    Cai, Y.3    Messing, E.M.4    Chang, C.5
  • 103
    • 24644501741 scopus 로고    scopus 로고
    • Upregulation of VEGF-C by androgen depletion: The involvement of IGF-IR-FOXO pathway
    • DOI 10.1038/sj.onc.1208693, PII 1208693
    • Li J, Wang E, Rinaldo F et al. Upregulation of VEGF-C by androgen depletion: the involvement of IGF-IR-FOXO pathway. Oncogene 2005; 24(35): 5510-5520. (Pubitemid 43080094)
    • (2005) Oncogene , vol.24 , Issue.35 , pp. 5510-5520
    • Li, J.1    Wang, E.2    Rinaldo, F.3    Datta, K.4
  • 104
    • 77951020901 scopus 로고    scopus 로고
    • Androgen depletion up-regulates cadherin-11 expression in prostate cancer
    • Lee YC, Cheng CJ, Huang M et al. Androgen depletion up-regulates cadherin-11 expression in prostate cancer. The Journal of Pathology 2010.
    • (2010) The Journal of Pathology
    • Lee, Y.C.1    Cheng, C.J.2    Huang, M.3
  • 105
    • 34250008248 scopus 로고    scopus 로고
    • Global analysis of differentially expressed genes in androgen-independent prostate cancer
    • DOI 10.1038/sj.pcan.4500933, PII 4500933
    • Wei Q, Li M, Fu X et al. Global analysis of differentially expressed genes in androgen-independent prostate cancer. Prostate Cancer and Prostatic Diseases 2007; 10(2): 167-174. (Pubitemid 46887067)
    • (2007) Prostate Cancer and Prostatic Diseases , vol.10 , Issue.2 , pp. 167-174
    • Wei, Q.1    Li, M.2    Fu, X.3    Tang, R.4    Na, Y.5    Jiang, M.6    Li, Y.7
  • 111
    • 39449115697 scopus 로고    scopus 로고
    • Androgen receptor and invasion in prostate cancer
    • DOI 10.1158/0008-5472.CAN-07-1929
    • Hara T, Miyazaki H, Lee A et al. Androgen receptor and invasion in prostate cancer. Cancer Research 2008; 68(4): 1128-1135. (Pubitemid 351272231)
    • (2008) Cancer Research , vol.68 , Issue.4 , pp. 1128-1135
    • Hara, T.1    Miyazaki, H.2    Lee, A.3    Tran, C.P.4    Reiter, R.E.5
  • 112
    • 57349120052 scopus 로고    scopus 로고
    • Improvement in predicting tumourigenic phenotype of androgen-insensitive human LNCaP prostatic cancer cell subline in recombination with rat urogenital sinus mesenchyme
    • Kanai M, Ishii K, Kanda H et al. Improvement in predicting tumourigenic phenotype of androgen-insensitive human LNCaP prostatic cancer cell subline in recombination with rat urogenital sinus mesenchyme. Cancer Science 2008; 99 (12): 2435-2443.
    • (2008) Cancer Science , vol.99 , Issue.12 , pp. 2435-2443
    • Kanai, M.1    Ishii, K.2    Kanda, H.3
  • 113
    • 0033000237 scopus 로고    scopus 로고
    • Malignant transformation of human prostatic epithelium is associated with the loss of androgen receptor immunoreactivity in the surrounding stroma
    • Olapade-Olaopa EO, MacKay EH, Taub NA et al. Malignant transformation of human prostatic epithelium is associated with the loss of androgen receptor immunoreactivity in the surrounding stroma. Clinical Cancer Research 1999; 5(3): 569-576. (Pubitemid 29131966)
    • (1999) Clinical Cancer Research , vol.5 , Issue.3 , pp. 569-576
    • Olapade-Olaopa, E.O.1    MacKay, E.H.2    Taub, N.A.3    Sandhu, D.P.S.4    Terry, T.R.5    Habib, F.K.6


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