메뉴 건너뛰기




Volumn 5, Issue 2, 2011, Pages 97-104

Continuation of mortality reduction after the end of randomized therapy in clinical trials of lipid-lowering therapy

Author keywords

Clinical trials; Legacy effect; Lipid lowering therapy; Mortality; Niacin; Statins

Indexed keywords

ANTILIPEMIC AGENT; ATORVASTATIN; FLUINDOSTATIN; GEMFIBROZIL; NICOTINIC ACID; PLACEBO; PRAVASTATIN; SIMVASTATIN;

EID: 79952550431     PISSN: 19332874     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacl.2011.01.006     Document Type: Article
Times cited : (18)

References (33)
  • 1
    • 38049033935 scopus 로고    scopus 로고
    • Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: A meta-analysis
    • Cholesterol Treatment Trialists' (CTT) Collaborators
    • Cholesterol Treatment Trialists' (CTT) Collaborators Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: a meta-analysis Lancet 371 2008 117 125
    • (2008) Lancet , vol.371 , pp. 117-125
  • 2
    • 77950935917 scopus 로고    scopus 로고
    • Relation of different measures of low-density lipoprotein cholesterol to risk of coronary artery disease and death in a meta-regression analysis of large-scale trials of statin therapy
    • J.R. Kizer, C. Madias, and B. Wilner Relation of different measures of low-density lipoprotein cholesterol to risk of coronary artery disease and death in a meta-regression analysis of large-scale trials of statin therapy Am J Cardiol 105 2010 1289 1296
    • (2010) Am J Cardiol , vol.105 , pp. 1289-1296
    • Kizer, J.R.1    Madias, C.2    Wilner, B.3
  • 3
    • 9444249842 scopus 로고    scopus 로고
    • Statins in stroke prevention and carotid atherosclerosis: Systematic review and up-to-date meta-analysis
    • DOI 10.1161/01.STR.0000147965.52712.fa
    • P. Amarenco, J. Labreuche, P. Lavallee, and P.J. Touboul Statins in stroke prevention and carotid atherosclerosis: systematic review and up-todate meta-analysis Stroke 35 2004 2902 2909 (Pubitemid 39565192)
    • (2004) Stroke , vol.35 , Issue.12 , pp. 2902-2909
    • Amarenco, P.1    Labreuche, J.2    Lavallee, P.3    Touboul, P.-J.4
  • 5
    • 56749106312 scopus 로고    scopus 로고
    • Jupiter Study Group. Rosuvastatin to prevent vascular events in men and women with elevated c-reactive protein
    • P.M. Ridker, E. Danielson, F.A. Fonseca, and J. Genest Jupiter Study Group. Rosuvastatin to prevent vascular events in men and women with elevated c-reactive protein N Engl J Med 359 2008 2195 2207
    • (2008) N Engl J Med , vol.359 , pp. 2195-2207
    • Ridker, P.M.1    Danielson, E.2    Fonseca, F.A.3    Genest, J.4
  • 6
    • 0021350001 scopus 로고
    • The Lipid Research Clinics Coronary Primary Prevention Trial Results. i Reduction in incidence of coronary heart disease
    • Lipid Research Clinics Program
    • Lipid Research Clinics Program The Lipid Research Clinics Coronary Primary Prevention Trial Results. I Reduction in incidence of coronary heart disease JAMA 251 1984 351 364
    • (1984) JAMA , vol.251 , pp. 351-364
  • 7
    • 33645225775 scopus 로고    scopus 로고
    • Lowering LDL - Not only how low, but how long
    • Brown MS, Goldstein JL. Lowering LDL - not only how low, but how long? Science. 200;311:1721-1723.
    • Science , vol.200-311 , pp. 1721-1723
    • Brown, M.S.1    Goldstein, J.L.2
  • 9
    • 78650414364 scopus 로고    scopus 로고
    • Persistence of mortality reduction after the end of randomized therapy in clinical trials of blood pressure lowering medications
    • W.J. Kostis, L. Thijs, T. Richart, J.B. Kostis, and J.A. Staessen Persistence of mortality reduction after the end of randomized therapy in clinical trials of blood pressure lowering medications Hypertension 56 2010 1060 1068
    • (2010) Hypertension , vol.56 , pp. 1060-1068
    • Kostis, W.J.1    Thijs, L.2    Richart, T.3    Kostis, J.B.4    Staessen, J.A.5
  • 10
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4s)
    • Scandinavian Simvastatin Survival Study Group
    • Scandinavian Simvastatin Survival Study Group Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4s) Lancet 344 1994 1383 1389
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 14
    • 0037420492 scopus 로고    scopus 로고
    • Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial - Lipid Lowering Arm (ASCOT-LLA): A multicentre randomised controlled trial
    • DOI 10.1016/S0140-6736(03)12948-0
    • P.S. Sever, B. Dahlöf, and N.R. Poulter Ascot Investigators. Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the anglo-scandinavian cardiac outcomes trial - lipid lowering arm (ascott-lla): a multicentre randomised controlled trial Lancet 361 2003 1149 1158 (Pubitemid 36398384)
    • (2003) Lancet , vol.361 , Issue.9364 , pp. 1149-1158
    • Sever, P.S.1    Dahlof, B.2    Poulter, N.R.3    Wedel, H.4    Beevers, G.5    Caulfield, M.6    Collins, R.7    Kjeldsen, S.E.8    Kristinsson, A.9    McInnes, G.T.10    Mehlsen, J.11    Nieminen, M.12    O'Brien, E.13    Ostergren, J.14
  • 15
    • 0016630250 scopus 로고
    • Clofibrate and niacin in coronary heart disease
    • The Coronary Drug Project Research Group
    • The Coronary Drug Project Research Group Clofibrate and niacin in coronary heart disease JAMA 231 1975 360 381
    • (1975) JAMA , vol.231 , pp. 360-381
  • 16
    • 0023001772 scopus 로고
    • Fifteen year mortality in Coronary Drug Project patients: Long-term benefit with niacin
    • P.L. Canner, K.G. Berge, and N.K. Wenger Fifteen year mortality in coronary drug project patients: long-term benefit with niacin J Am Coll Cardiol 8 1986 1245 1255 (Pubitemid 17208898)
    • (1986) Journal of the American College of Cardiology , vol.8 , Issue.6 , pp. 1245-1255
    • Canner, P.L.1    Berge, K.G.2    Wenger, N.K.3
  • 17
    • 0026747150 scopus 로고
    • The Lipid Research Clinics Coronary Primary Prevention Trial. Results of 6 years of post-trial follow-up
    • The Lipid Research Clinics Investigators
    • The Lipid Research Clinics Investigators The Lipid Research Clinics Coronary Primary Prevention Trial. Results of 6 years of post-trial follow-up Arch Intern Med 152 1992 1399 1410
    • (1992) Arch Intern Med , vol.152 , pp. 1399-1410
  • 18
    • 0023232216 scopus 로고
    • Helsinki Heart Study. Primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia
    • M.H. Frick, O. Elo, and K. Haapa Helsinki Heart Study. Primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia N Engl J Med 317 1987 1237 1245
    • (1987) N Engl J Med , vol.317 , pp. 1237-1245
    • Frick, M.H.1    Elo, O.2    Haapa, K.3
  • 19
    • 33645729392 scopus 로고    scopus 로고
    • Gemfibrozil in the treatment of dyslipidemia. An 18-year mortality follow-up of the Helsinki heart study
    • L. Tenkanen, M. Manttari, P.T. Kovanen, H. Virkkunen, and V. Manninen Gemfibrozil in the treatment of dyslipidemia. An 18-year mortality follow-up of the Helsinki heart study Arch Intern Med 166 2006 743 748
    • (2006) Arch Intern Med , vol.166 , pp. 743-748
    • Tenkanen, L.1    Manttari, M.2    Kovanen, P.T.3    Virkkunen, H.4    Manninen, V.5
  • 20
    • 0032487931 scopus 로고    scopus 로고
    • Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels
    • The Long-Term Intervention With Pravastatin in Ischaemic Disease (Lipid) Study Group
    • The Long-Term Intervention With Pravastatin in Ischaemic Disease (Lipid) Study Group Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels N Engl J Med 339 1998 1349 1357
    • (1998) N Engl J Med , vol.339 , pp. 1349-1357
  • 21
    • 0037140177 scopus 로고    scopus 로고
    • Long-term effectiveness and safety of pravastatin in 9014 patients with coronary heart disease and average cholesterol concentrations: The lipid trial follow-up
    • The Lipid Study Group
    • The Lipid Study Group Long-term effectiveness and safety of pravastatin in 9014 patients with coronary heart disease and average cholesterol concentrations: the lipid trial follow-up Lancet 359 2002 1379 1387
    • (2002) Lancet , vol.359 , pp. 1379-1387
  • 22
    • 0028883828 scopus 로고
    • Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia
    • J. Shepherd, S.M. Cobbe, and I. Ford Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia N Engl J Med 333 1995 1301 1307
    • (1995) N Engl J Med , vol.333 , pp. 1301-1307
    • Shepherd, J.1    Cobbe, S.M.2    Ford, I.3
  • 25
    • 0033934949 scopus 로고    scopus 로고
    • Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis
    • S. Duval, and R. Tweedie Trim and fill: a simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis Biometrics 56 2000 455 463 (Pubitemid 30422636)
    • (2000) Biometrics , vol.56 , Issue.2 , pp. 455-463
    • Duval, S.1    Tweedie, R.2
  • 26
    • 33746341926 scopus 로고
    • The "file drawer problem" and tolerance for null results
    • R. Rosenthal The "file drawer problem" and tolerance for null results Psychol Bull 86 1979 638 641
    • (1979) Psychol Bull , vol.86 , pp. 638-641
    • Rosenthal, R.1
  • 27
    • 0000519782 scopus 로고
    • A Fail-safe n for effect size in meta-analysis
    • R.G. Orwin A Fail-safe n for effect size in meta-analysis J Educ Stat 8 1983 157 159
    • (1983) J Educ Stat , vol.8 , pp. 157-159
    • Orwin, R.G.1
  • 30
    • 26844564725 scopus 로고    scopus 로고
    • The potential relevance of the multiple lipid-independent (Pleiotropic) effects of statins in the management of acute coronary syndromes
    • DOI 10.1016/j.jacc.2005.05.086, PII S0735109705017730
    • K.K. Ray, and C.P. Cannon The potential relevance of the multiple lipid-independent (pleiotropic) effects of statins in the management of acute coronary syndromes J Am Coll Cardiol 46 2005 1425 1433 (Pubitemid 41446176)
    • (2005) Journal of the American College of Cardiology , vol.46 , Issue.8 , pp. 1425-1433
    • Ray, K.K.1    Cannon, C.P.2
  • 31
    • 33645103550 scopus 로고    scopus 로고
    • Sequence variations in PCSK9, low LDL, and protection against coronary heart disease
    • J.C. Cohen, E. Boerwindle, T.H. Mosley Jr., and H.H. Hobbs Sequence variations in PCSK9, low LDL, and protection against coronary heart disease N Engl J Med 354 2006 1264 1272
    • (2006) N Engl J Med , vol.354 , pp. 1264-1272
    • Cohen, J.C.1    Boerwindle, E.2    Mosley Jr., T.H.3    Hobbs, H.H.4
  • 32
    • 53749094476 scopus 로고    scopus 로고
    • UKPDS and the legacy effect
    • J. Chalmers, and M.E. Cooper UKPDS and the legacy effect N Engl J Med 359 2008 1618 1620
    • (2008) N Engl J Med , vol.359 , pp. 1618-1620
    • Chalmers, J.1    Cooper, M.E.2
  • 33
    • 70449377075 scopus 로고    scopus 로고
    • Age-neutral guidelines for the primary prevention of cardiovascular disease
    • W.J. Kostis, and J.B. Kostis Age-neutral guidelines for the primary prevention of cardiovascular disease J Clin Hypertens 11 2009 644 645
    • (2009) J Clin Hypertens , vol.11 , pp. 644-645
    • Kostis, W.J.1    Kostis, J.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.