Plant-based Rasayana drugs from Ayurveda

Chinese Journal of Integrative Medicine

Volumn 17, Issue 2, 2011, Pages 88-94

  Balasubramani, Subramani Paranthaman ^a   Venkatasubramanian, Padma ^a   Kukkupuni, Subrahmanya Kumar ^a   Patwardhan, Bhushan ^a  

^a Institute of Ayurveda and Integrative Medicine   (India)

Author keywords

Anti ageing; Anti oxidant; Ayurveda; Immunomodulation; Rasayana; Rejuvenation

Indexed keywords

AMRITHAPRASAM; ANACYCLUS PYRETHRUM EXTRACT; ASPARAGUS RACEMOSUS EXTRACT; ASWAGANDHA RASAYANA; BACOPA MONNIERI EXTRACT; BRAHMA RASAYANA; BRAHMI; CENTELLA ASIATICA EXTRACT; CHLOROPHYTUM BORIVILIANUM EXTRACT; CHYAVANAPRASAM; CONVOLVULUS PLURICAULIS EXTRACT; EMBLICA OFFICINALIS EXTRACT; HERBACEOUS AGENT; MANDUKAPARNI; MEDHYA RASAYANA; NARASIMHA RASAYANA; PIPPALI RASAYANA; PLACEBO; PLANT EXTRACT; SANKHAPUSPI; TERMINALIA BELLIRICA EXTRACT; TERMINALIA CHEBULA EXTRACT; TINOSPORA CORDIFOLIA EXTRACT; TRIPHALA; UNCLASSIFIED DRUG; WITHANIA SOMNIFERA EXTRACT;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; AYURVEDA; DRUG FORMULATION; DRUG POTENTIATION; DRUG RESEARCH; GIARDIASIS; HUMAN; IMMUNOMODULATION; NERVOUS SYSTEM FUNCTION; PRIORITY JOURNAL; RADIATION PROTECTION; RASAYANA TANTRA; REVIEW; SEXUAL AROUSAL; ULCEROGENESIS;

ANIMALS; ANTI-ULCER AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ANTIPARASITIC AGENTS; APHRODISIACS; FREE RADICAL SCAVENGERS; GIARDIASIS; HERBAL MEDICINE; HUMANS; IMMUNOLOGIC FACTORS; MEDICINE, AYURVEDIC; MODELS, BIOLOGICAL; NEUROPROTECTIVE AGENTS; PLANT PREPARATIONS; RADIATION-PROTECTIVE AGENTS;

EID: 79952549972     PISSN: 16720415     EISSN: 19930402     Source Type: Journal    
DOI: 10.1007/s11655-011-0659-5     Document Type: Review

References (41)

1. Vidyanath R, Nishteswar K. A handbook of history of Ayurveda. Varanasi: Chowkambha Sanskrit Series Office;2006:1-386.
2. Sharma PV, ed. Susruta-Samita with Dalhana's commentary. Varanasi: Chowkambha Bharati Academy;1999:1-173.
3. Jayasundar R. Ayurveda: a distinctive approach to health and disease. Curr Sci 2010;98:908-914.
4. Shukla MP. The concept of Rasayana therapy in Indian medicine and comprehensive approach to its evaluation. Ind J His Med 1971;16:42-46.
5. Sharma PV, ed. History of medicine in India. New Delhi: Indian National Science Academy;1992:353-356.
6. Valko M, Leibfritz D, Moncol J, Cronin MTD, Mazur M, Telser J. Free radicals and anti-oxidants in normal physiological functions and human disease. IJBCB 2007;39:44-84. (Pubitemid 44566469)
7. Vayalil PK, Kuttan G, Kuttan R. Rasayanas: Evidence for the concepts of prevention of diseases. Am J Chin Med 2002;30:155-171. (Pubitemid 41760422)
8. Govindarajan R, Vijayakumar M, Pushpangandan P. Antioxidant approach to disease management and the role of 'Rasayana' herbs of Ayurveda. J Ethnopharmacol 2005;99:165-178.
9. Gupta SK, Dua A, Vohra BP. Withania somnifera (Ashwagandha) attenuates antioxidant defense in aged spinal cord and inhibits copper induced lipid peroxidation and protein oxidative modifications. Drug Metabol Drug Interact 2003;19:211-222. (Pubitemid 37505163)
10. Bhattacharya A, Ghosal S, Bhattacharya SK. Antioxidant activity of tannoid principles of Emblica officinalis (amla) in chronic stress induced changes in rat brain. Indian J Exp Biol 2000;38:877-880.
11. Mangathayaru K, Umadevi M, Reddy CU. Evaluation of the immunomodulatory and DNA protective activities of the shoots of Cynodon dactylon. J Ethnopharmacol 2009;123:181-184.
12. Gautam M, Saha S, Bani S, Kaul A, Mishra S, Patil D, et al. Immunomodulatory activity of Asparagus racemosus on systemic Th1/Th2 immunity: implications for immunoadjuvant potential. J Ethnopharmacol 2009;121:241-247.
13. Sharma V, Thakur M, Chauhan NS, Dixit VK. Effects of petroleum ether extract of Anacyclus pyrethrum DC. on sexual behavior in male rats. J Chin Integr Med 2010;8:767-773.
14. Inaba R, Mirbod SM, Sugiura H. Effects of Maharishi Amrit Kalash 5 as an Ayurvedic herbal food supplement on immune functions in aged mice. BMC Complement Altern Med 2005;5:8.
15. Gautam M, Diwanay S, Gairola S, Shinde Y, Patki P, Patwardhan B. Immunoadjuvant potential of Asparagus racemosus aqueous extract in experimental system. J Ethnopharmacol 2004;91:251-255. (Pubitemid 38561122)
16. Gautam M, Diwanay SS, Gairola S, Shinde YS, Jadhav SS, Patwardhan BK. Immune response modulation to DPT vaccine by aqueous extract of Withania somnifera in experimental system. Int Immunopharmacol 2004;4:841-849. (Pubitemid 38607387)
17. Murthy VMR, Ranjekar PK, Ramassamy C, Deshpande M. Scientific basis for the use of Indian Ayurvedic medicinal plants in the treatment of neurodegenerative disorders: ashwagandha. Cent Nerv Syst Agents Med Chem 2010;10:238-246.
18. Singh RH, Narsimhamurthy K, Singh G. Neuronutrient impact of Ayurvedic Rasayana therapy in brain aging. Biogerontol 2008;9:369-374.
19. Kumar V. Potential medicinal plants for CNS disorders: an overview. Phytother Res 2006;20:1023-1035. (Pubitemid 44951704)
20. Kulkarni SK, Dhir A. Withania somnifera: an Indian ginseng. Prog Europsychopharmacol Biol Psychiatry 2008;32:1093-1105.
21. Ojha R, Sahu AN, Muruganandam AV, Singh GK, Krishnamurthy S. Asparagus recemosus enhances memory and protects against amnesia in rodent models. Brain Cogn 2010;74:1-9.
22. Joshi H, Parle M. Brahmi rasayana improves learning and memory in mice. Evid Based Complement Alternat Med 2006;3:79-85. (Pubitemid 43999655)
23. Sharma HM, Hanna AN, Kauffman EM, Newman HA. Effect of herbal mixture student Rasayana on lipoxygenase activity and lipid peroxidation. Free Radic Biol Med 1995;18:687-697.
24. Li PP. Could we use clinical benefits to evaluate the effects of Chinese medicine on the treatment of cancer? Chin J Integr Med 2010;16:9-10.
25. Rekha PS, Kuttan G, Kuttan R. Effect of Brahma rasayana on antioxidant systems and cytokine levels in mice during cyclophosphamide administration. J Exp Clin Cancer Res 2001;20:219-223. (Pubitemid 32641064)
26. Jagetia GC, Malagi KJ, Baliga MS, Venkatesh P, Veruva RR. Triphala, an Ayurvedic rasayana drug, protects mice against radiation-induced lethality by free-radical scavenging. J Altern Complement Med 2004;10:971-978. (Pubitemid 40180003)
27. Jaget ia GC, Bal iga MS. The evaluat ion of the radioprotective effect of chyavanaprasha (an Ayurvedic Rasayana drug) in mice exposed to lethal dose of gammaradiation: a preliminary study. Phytother Res 2004;18:14-18.
28. Thakur M, Chauhan NS, Bhargava S, Dixit VK. A comparative study on aphrodisiac activity of some Ayurvedic herbs in male albino rats. Arch Sex Behav 2009;38:1009-1015.
29. Chauhan NS, Sharma V, Thakur M, Dixit VK. Curculigo orchioides: the black gold with numerous health benefits. J Chin Integr Med 2010;8:613-623.
30. Sairam K, Priyambada S, Aryya NC, Goel RK. Gastroduodenal ulcer protective activity of Asparagus racemosus: an experimental, biochemical and histological study. J Ethnopharmacol 2003;86:1-10. (Pubitemid 36398652)
31. Sairam K, Rao CV, Babu MD, Goel RK. Prophylactic and curative effects of Bacopa monniera in gastric ulcer models. Phytomedicine 2001;8:423-430. (Pubitemid 34052596)
32. Agarwal AK, Singh M, Gupta N, Saxena R, Puri A, Verma AK, et al. Management of giardiasis by an immunomodulatory herbal drug Pippali rasayana. J Ethnopharmacol 1994;44:143-146.
33. Agarwal AK, Tripathi DM, Sahai R, Gupta N, Saxena RP, Puri A, et al. Management of giardiasis by a herbal drug 'Pippali Rasayana': a clinical study. J Ethnopharmacol 1997;56:233-236.
34. Hawrelak J. Giardiasis: pathophysiology and management. Altern Med Rev 2003;8:129-142. (Pubitemid 36676181)
35. Menon LG, Kuttan R, Kuttan G. Effect of rasayanas in the inhibition of lung metastasis induced by B16F-10 melanoma cells. J Exp Clin Cancer Res 1997;16:365-368. (Pubitemid 28083534)
36. Kumar VP, Kuttan R, Kuttan G. Effect of "rasayanas", a herbal drug preparation on cell-mediated immune responses in tumour bearing mice. Ind J Exp Biol 1999;37:23-26.
37. Kumar VP, Kuttan R, Kuttan G. Effect of "rasayanas", a herbal drug preparation on immune responses and its significance in cancer treatment. Ind J Exp Biol 1999;37:27-31.
38. Gaddipati JP, Rajeshkumar NV, Thangapazham RL, Sharma A, Warren J, Mog SR, et al. Protective effect of a polyherbal preparation, Brahma rasayana against tumor growth and lung metastasis in rat prostate model system. J Exp Ther Oncol 2004;4:203-212. (Pubitemid 39557171)
39. Thangapazham RL, Sharma A, Gaddipati JP, Singh AK, Maheshwari RK. Inhibition of tumor angiogenesis by Brahma Rasayana (BR). J Exp Ther Oncol 2006;6:13-21. (Pubitemid 46068189)
40. Diwanay S, Chitre D, Patwardhan B. Immunoprotection by botanical drugs in cancer chemotherapy. J Ethnopharmacol 2004;90:49-55. (Pubitemid 38091685)
41. Patwardhan B, Mashelkar RA. Traditional medicine-inspired approaches to drug discovery: can Ayurveda show the way forward? Drug Disc Today 2009;14:804-811.