메뉴 건너뛰기




Volumn 39, Issue 4, 2011, Pages 451-458

Endotoxin release in cardiac surgery with cardiopulmonary bypass: Pathophysiology and possible therapeutic strategies. An update

Author keywords

Cardiopulmonary bypass; Endotoxin release; Inflammatory response syndrome

Indexed keywords

ALKALINE PHOSPHATASE; AMPHOTERICIN B; C REACTIVE PROTEIN; CD14 ANTIGEN; COLISTIN; CORTICOSTEROID; ENDOTOXIN; ENDOTOXIN ANTIBODY; ERITORAN; HUMORAL ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8; KETANSERIN; LIPOPOLYSACCHARIDE; LIPOPOLYSACCHARIDE BINDING PROTEIN; METHYLPREDNISOLONE; NEOMYCIN; PENTRAXIN; PICOSULFATE SODIUM; PLACEBO; POLYMYXIN B; TAUROLIDINE; TOBRAMYCIN; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG;

EID: 79952535561     PISSN: 10107940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejcts.2010.06.011     Document Type: Review
Times cited : (42)

References (63)
  • 1
    • 0036168128 scopus 로고    scopus 로고
    • Cardiopulmonary bypass induced inflammation: pathophysiology and treatment. An update
    • Paparella D., Yau T.M., Young E. Cardiopulmonary bypass induced inflammation: pathophysiology and treatment. An update. Eur J Cardiothorac Surg 2002, 21:232-244.
    • (2002) Eur J Cardiothorac Surg , vol.21 , pp. 232-244
    • Paparella, D.1    Yau, T.M.2    Young, E.3
  • 4
    • 0025285857 scopus 로고
    • Biochemistry of endotoxins
    • Raetz C.R. Biochemistry of endotoxins. Annu Rev Biochem 1990, 59:129-170.
    • (1990) Annu Rev Biochem , vol.59 , pp. 129-170
    • Raetz, C.R.1
  • 5
    • 0033574415 scopus 로고    scopus 로고
    • Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction
    • Chow J.C., Young D.W., Golenbock D.T., Christ W.J., Gusovsky F. Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction. J Biol Chem 1999, 274:10689-10692.
    • (1999) J Biol Chem , vol.274 , pp. 10689-10692
    • Chow, J.C.1    Young, D.W.2    Golenbock, D.T.3    Christ, W.J.4    Gusovsky, F.5
  • 10
    • 0028335977 scopus 로고
    • Effects of cardiopulmonary bypass on gut blood flow, oxygen utilization, and intramucosal pH
    • Ohri S.K., Becket J., Brannan J., Keogh B.E., Taylor K.M. Effects of cardiopulmonary bypass on gut blood flow, oxygen utilization, and intramucosal pH. Ann Thorac Surg 1994, 57:1193-1199.
    • (1994) Ann Thorac Surg , vol.57 , pp. 1193-1199
    • Ohri, S.K.1    Becket, J.2    Brannan, J.3    Keogh, B.E.4    Taylor, K.M.5
  • 11
    • 0029988572 scopus 로고    scopus 로고
    • Intestinal permeability, gastric intramucosal pH, and systemic endotoxemia in patients undergoing cardiopulmonary bypass
    • Riddington D.W., Venkatesh B., Boivin C.M., Bonser R.S., Elliott T.S., Marshall T., Mountford P.J., Bion J.F. Intestinal permeability, gastric intramucosal pH, and systemic endotoxemia in patients undergoing cardiopulmonary bypass. JAMA 1996, 275:1007-1012.
    • (1996) JAMA , vol.275 , pp. 1007-1012
    • Riddington, D.W.1    Venkatesh, B.2    Boivin, C.M.3    Bonser, R.S.4    Elliott, T.S.5    Marshall, T.6    Mountford, P.J.7    Bion, J.F.8
  • 12
    • 0020644991 scopus 로고
    • Absorption of 51chromium-labeled ethylenediaminetetraacetate in inflammatory bowel disease
    • Bjarnason I., O'Morain C., Levi A.J., Peters T.J. Absorption of 51chromium-labeled ethylenediaminetetraacetate in inflammatory bowel disease. Gastroenterology 1983, 85:318-322.
    • (1983) Gastroenterology , vol.85 , pp. 318-322
    • Bjarnason, I.1    O'Morain, C.2    Levi, A.J.3    Peters, T.J.4
  • 13
    • 0030696108 scopus 로고    scopus 로고
    • Gastrointestinal permeability in cardiac surgery patients, the interpretation of dual-sugar absorption studies
    • Oudemans-van Straaten H.M., Hoek F.J., van Deventer S.J. Gastrointestinal permeability in cardiac surgery patients, the interpretation of dual-sugar absorption studies. Intensive Care Med 1997, 23:1101-1102.
    • (1997) Intensive Care Med , vol.23 , pp. 1101-1102
    • Oudemans-van Straaten, H.M.1    Hoek, F.J.2    van Deventer, S.J.3
  • 17
    • 0033835438 scopus 로고    scopus 로고
    • Endotoxin in pooled pericardial blood contributes to the systemic inflammatory response during cardiac surgery
    • Spanier T., Tector K., Schwartz G., Chen J., Oz M., Beck J., Mongero L. Endotoxin in pooled pericardial blood contributes to the systemic inflammatory response during cardiac surgery. Perfusion 2000, 15:427-431.
    • (2000) Perfusion , vol.15 , pp. 427-431
    • Spanier, T.1    Tector, K.2    Schwartz, G.3    Chen, J.4    Oz, M.5    Beck, J.6    Mongero, L.7
  • 18
    • 0018909678 scopus 로고
    • [Limulus amoebocyte lysate (LAL) test for demonstration of endotoxins]
    • Baek L., Tvede M., Mikkelsen T. [Limulus amoebocyte lysate (LAL) test for demonstration of endotoxins]. Ugeskr Laeger 1980, 142:1405-1409.
    • (1980) Ugeskr Laeger , vol.142 , pp. 1405-1409
    • Baek, L.1    Tvede, M.2    Mikkelsen, T.3
  • 20
    • 0033828733 scopus 로고    scopus 로고
    • Plasma endotoxin concentrations during cardiac surgery may be related to atherosclerosis
    • Videm V., Svennevig J.L., Fosse E., Mohr B., Aasen A.O. Plasma endotoxin concentrations during cardiac surgery may be related to atherosclerosis. Perfusion 2000, 15:421-426.
    • (2000) Perfusion , vol.15 , pp. 421-426
    • Videm, V.1    Svennevig, J.L.2    Fosse, E.3    Mohr, B.4    Aasen, A.O.5
  • 21
    • 33646817775 scopus 로고    scopus 로고
    • Human endotoxemia: a model for mechanistic insight and therapeutic targeting
    • Lowry S.F. Human endotoxemia: a model for mechanistic insight and therapeutic targeting. Shock 2005, 24(Suppl. 1):94-100.
    • (2005) Shock , vol.24 , Issue.SUPPL. 1 , pp. 94-100
    • Lowry, S.F.1
  • 23
    • 0033854737 scopus 로고    scopus 로고
    • Endotoxin desensitization of human mononuclear cells after cardiopulmonary bypass: role of humoral factors
    • Grundmann U., Rensing H., Adams H.A., Falk S., Wendler O., Ebinger N., Bauer M. Endotoxin desensitization of human mononuclear cells after cardiopulmonary bypass: role of humoral factors. Anesthesiology 2000, 93:359-369.
    • (2000) Anesthesiology , vol.93 , pp. 359-369
    • Grundmann, U.1    Rensing, H.2    Adams, H.A.3    Falk, S.4    Wendler, O.5    Ebinger, N.6    Bauer, M.7
  • 24
    • 1842555390 scopus 로고    scopus 로고
    • Compartmentalization of tolerance to endotoxin
    • Fitting C., Dhawan S., Cavaillon J.M. Compartmentalization of tolerance to endotoxin. J Infect Dis 2004, 189:1295-1303.
    • (2004) J Infect Dis , vol.189 , pp. 1295-1303
    • Fitting, C.1    Dhawan, S.2    Cavaillon, J.M.3
  • 25
    • 9844224250 scopus 로고
    • Bacterial endotoxins: lipopolysaccharides from genes to therapy
    • John Wiley and Sons, New York, J. Levin, C.R. Alving, R.S. Munford, H. Redl (Eds.)
    • Barclay G.R. Bacterial endotoxins: lipopolysaccharides from genes to therapy. Progress in clinical and biological research 1995, 263-272. John Wiley and Sons, New York. J. Levin, C.R. Alving, R.S. Munford, H. Redl (Eds.).
    • (1995) Progress in clinical and biological research , pp. 263-272
    • Barclay, G.R.1
  • 26
    • 0023189842 scopus 로고
    • Endotoxin-polymyxin complexes in an improved enzyme-linked immunosorbent assay for IgG antibodies in blood donor sera to gram-negative endotoxin core glycolipids
    • Scott B.B., Barclay G.R. Endotoxin-polymyxin complexes in an improved enzyme-linked immunosorbent assay for IgG antibodies in blood donor sera to gram-negative endotoxin core glycolipids. Vox Sang 1987, 52:272-280.
    • (1987) Vox Sang , vol.52 , pp. 272-280
    • Scott, B.B.1    Barclay, G.R.2
  • 28
    • 0030726016 scopus 로고    scopus 로고
    • Relationship between preoperative endotoxin immune status, gut perfusion, and outcome from cardiac valve replacement surgery
    • Hamilton-Davies C., Barclay G.R., Cardigan R.A., McDonald S.J., Purdy G., Machin S.J., Webb A.R. Relationship between preoperative endotoxin immune status, gut perfusion, and outcome from cardiac valve replacement surgery. Chest 1997, 112:1189-1196.
    • (1997) Chest , vol.112 , pp. 1189-1196
    • Hamilton-Davies, C.1    Barclay, G.R.2    Cardigan, R.A.3    McDonald, S.J.4    Purdy, G.5    Machin, S.J.6    Webb, A.R.7
  • 33
    • 0028844569 scopus 로고
    • Steroid inhibition of cytokine-mediated vasodilation after warm heart surgery
    • Teoh K.H., Bradley C.A., Gauldie J., Burrows H. Steroid inhibition of cytokine-mediated vasodilation after warm heart surgery. Circulation 1995, 92:II347-II353.
    • (1995) Circulation , vol.92
    • Teoh, K.H.1    Bradley, C.A.2    Gauldie, J.3    Burrows, H.4
  • 34
    • 0029035105 scopus 로고
    • Methylprednisolone inhibits increase of interleukin 8 and 6 during open heart surgery
    • Kawamura T., Inada K., Okada H., Okada K., Wakusawa R. Methylprednisolone inhibits increase of interleukin 8 and 6 during open heart surgery. Can J Anaesth 1995, 42:399-403.
    • (1995) Can J Anaesth , vol.42 , pp. 399-403
    • Kawamura, T.1    Inada, K.2    Okada, H.3    Okada, K.4    Wakusawa, R.5
  • 36
    • 0031808481 scopus 로고    scopus 로고
    • Pulmonary effects of methylprednisolone in patients undergoing coronary artery bypass grafting and early tracheal extubation
    • Chaney M.A., Nikolov M.P., Blakeman B., Bakhos M., Slogoff S. Pulmonary effects of methylprednisolone in patients undergoing coronary artery bypass grafting and early tracheal extubation. Anesth Analg 1998, 87:27-33.
    • (1998) Anesth Analg , vol.87 , pp. 27-33
    • Chaney, M.A.1    Nikolov, M.P.2    Blakeman, B.3    Bakhos, M.4    Slogoff, S.5
  • 40
    • 0027497781 scopus 로고
    • Taurine in development
    • Sturman J.A. Taurine in development. Physiol Rev 1993, 73:119-147.
    • (1993) Physiol Rev , vol.73 , pp. 119-147
    • Sturman, J.A.1
  • 41
    • 77955923360 scopus 로고    scopus 로고
    • The antiendotoxin agent taurolidine potentially reduces ischemia/reperfusion injury through its metabolite taurine
    • doi:10.10.16/j.surg.2010.01.006
    • Doddakula K.K., Neary P.M., Wang J.H., Sookhai S., O'Donnell A., Aherne T., Bouchier-Hayes D.J., Redmond H.P. The antiendotoxin agent taurolidine potentially reduces ischemia/reperfusion injury through its metabolite taurine. Surgery 2010, doi:10.10.16/j.surg.2010.01.006.
    • (2010) Surgery
    • Doddakula, K.K.1    Neary, P.M.2    Wang, J.H.3    Sookhai, S.4    O'Donnell, A.5    Aherne, T.6    Bouchier-Hayes, D.J.7    Redmond, H.P.8
  • 44
    • 0036152703 scopus 로고    scopus 로고
    • No effect of preoperative selective gut decontamination on endotoxemia and cytokine activation during cardiopulmonary bypass: a randomized, placebo-controlled study
    • Bouter H., Schippers E.F., Luelmo S.A., Versteegh M.I., Ros P., Guiot H.F., Frolich M., van Dissel J.T. No effect of preoperative selective gut decontamination on endotoxemia and cytokine activation during cardiopulmonary bypass: a randomized, placebo-controlled study. Crit Care Med 2002, 30:38-43.
    • (2002) Crit Care Med , vol.30 , pp. 38-43
    • Bouter, H.1    Schippers, E.F.2    Luelmo, S.A.3    Versteegh, M.I.4    Ros, P.5    Guiot, H.F.6    Frolich, M.7    van Dissel, J.T.8
  • 45
    • 0028262335 scopus 로고
    • Endotoxemia, complement, and white blood cell activation in cardiac surgery: a randomized trial of laxatives and pulsatile perfusion
    • Taggart D.P., Sundaram S., McCartney C., Bowman A., McIntyre H., Courtney J.M., Wheatley D.J. Endotoxemia, complement, and white blood cell activation in cardiac surgery: a randomized trial of laxatives and pulsatile perfusion. Ann Thorac Surg 1994, 57:376-382.
    • (1994) Ann Thorac Surg , vol.57 , pp. 376-382
    • Taggart, D.P.1    Sundaram, S.2    McCartney, C.3    Bowman, A.4    McIntyre, H.5    Courtney, J.M.6    Wheatley, D.J.7
  • 47
    • 33846456617 scopus 로고    scopus 로고
    • A phase II, double-blind, placebo-controlled, ascending-dose study of Eritoran (E5564), a lipid A antagonist, in patients undergoing cardiac surgery with cardiopulmonary bypass
    • Bennett-Guerrero E., Grocott H.P., Levy J.H., Stierer K.A., Hogue C.W., Cheung A.T., Newman M.F., Carter A.A., Rossignol D.P., Collard C.D. A phase II, double-blind, placebo-controlled, ascending-dose study of Eritoran (E5564), a lipid A antagonist, in patients undergoing cardiac surgery with cardiopulmonary bypass. Anesth Analg 2007, 104:378-383.
    • (2007) Anesth Analg , vol.104 , pp. 378-383
    • Bennett-Guerrero, E.1    Grocott, H.P.2    Levy, J.H.3    Stierer, K.A.4    Hogue, C.W.5    Cheung, A.T.6    Newman, M.F.7    Carter, A.A.8    Rossignol, D.P.9    Collard, C.D.10
  • 48
    • 0030970524 scopus 로고    scopus 로고
    • A physiologic function for alkaline phosphatase: endotoxin detoxification
    • Poelstra K., Bakker W.W., Klok P.A., Hardonk M.J., Meijer D.K. A physiologic function for alkaline phosphatase: endotoxin detoxification. Lab Invest 1997, 76:319-327.
    • (1997) Lab Invest , vol.76 , pp. 319-327
    • Poelstra, K.1    Bakker, W.W.2    Klok, P.A.3    Hardonk, M.J.4    Meijer, D.K.5
  • 50
    • 36749024487 scopus 로고    scopus 로고
    • Intestinal alkaline phosphatase detoxifies lipopolysaccharide and prevents inflammation in zebrafish in response to the gut microbiota
    • Bates J.M., Akerlund J., Mittge E., Guillemin K. Intestinal alkaline phosphatase detoxifies lipopolysaccharide and prevents inflammation in zebrafish in response to the gut microbiota. Cell Host Microbe 2007, 2:371-382.
    • (2007) Cell Host Microbe , vol.2 , pp. 371-382
    • Bates, J.M.1    Akerlund, J.2    Mittge, E.3    Guillemin, K.4
  • 51
    • 0142179149 scopus 로고    scopus 로고
    • Calf intestinal alkaline phosphatase, a novel therapeutic drug for lipopolysaccharide (LPS)-mediated diseases, attenuates LPS toxicity in mice and piglets
    • Beumer C., Wulferink M., Raaben W., Fiechter D., Brands R., Seinen W. Calf intestinal alkaline phosphatase, a novel therapeutic drug for lipopolysaccharide (LPS)-mediated diseases, attenuates LPS toxicity in mice and piglets. J Pharmacol Exp Ther 2003, 307:737-744.
    • (2003) J Pharmacol Exp Ther , vol.307 , pp. 737-744
    • Beumer, C.1    Wulferink, M.2    Raaben, W.3    Fiechter, D.4    Brands, R.5    Seinen, W.6
  • 53
    • 70349229430 scopus 로고    scopus 로고
    • Clinical experience with a novel endotoxin adsorbtion device in patients undergoing cardiac surgery
    • Blomquist S., Gustafsson V., Manolopoulos T., Pierre L. Clinical experience with a novel endotoxin adsorbtion device in patients undergoing cardiac surgery. Perfusion 2009, 24:13-17.
    • (2009) Perfusion , vol.24 , pp. 13-17
    • Blomquist, S.1    Gustafsson, V.2    Manolopoulos, T.3    Pierre, L.4
  • 55
    • 0034869816 scopus 로고    scopus 로고
    • Lipopolysaccharide: neutralization by polymyxin B shuts down the signaling pathway of nuclear factor kappaB in peripheral blood mononuclear cells, even during activation
    • Tsuzuki H., Tani T., Ueyama H., Kodama M. Lipopolysaccharide: neutralization by polymyxin B shuts down the signaling pathway of nuclear factor kappaB in peripheral blood mononuclear cells, even during activation. J Surg Res 2001, 100:127-134.
    • (2001) J Surg Res , vol.100 , pp. 127-134
    • Tsuzuki, H.1    Tani, T.2    Ueyama, H.3    Kodama, M.4
  • 57
    • 38949140894 scopus 로고    scopus 로고
    • Endotoxin removal with a polymyxin B-immobilized hemoperfusion cartridge improves cardiopulmonary function after cardiopulmonary bypass
    • Ohki S., Oshima K., Takeyoshi I., Matsumoto K., Morishita Y. Endotoxin removal with a polymyxin B-immobilized hemoperfusion cartridge improves cardiopulmonary function after cardiopulmonary bypass. J Surg Res 2008, 145:74-79.
    • (2008) J Surg Res , vol.145 , pp. 74-79
    • Ohki, S.1    Oshima, K.2    Takeyoshi, I.3    Matsumoto, K.4    Morishita, Y.5
  • 58
    • 34548452213 scopus 로고    scopus 로고
    • Impact of off-pump coronary artery bypass surgery on systemic inflammation: current best available evidence
    • Raja S.G., Berg G.A. Impact of off-pump coronary artery bypass surgery on systemic inflammation: current best available evidence. J Card Surg 2007, 22:445-455.
    • (2007) J Card Surg , vol.22 , pp. 445-455
    • Raja, S.G.1    Berg, G.A.2
  • 61
    • 0039435423 scopus 로고    scopus 로고
    • Endotoxemia and cytokine generation in cardiac surgery in relation to flow mode and duration of cardiopulmonary bypass
    • Neuhof C., Wendling J., Dapper F., Bauer J., Zickmann B., Jochum M., Tillmanns H., Neuhoft H. Endotoxemia and cytokine generation in cardiac surgery in relation to flow mode and duration of cardiopulmonary bypass. Shock 2001, 16(Suppl. 1):39-43.
    • (2001) Shock , vol.16 , Issue.SUPPL. 1 , pp. 39-43
    • Neuhof, C.1    Wendling, J.2    Dapper, F.3    Bauer, J.4    Zickmann, B.5    Jochum, M.6    Tillmanns, H.7    Neuhoft, H.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.