Solid-state NMR spectroscopic investigation of Aβ protofibrils: Implication of a β-sheet remodeling upon maturation into terminal amyloid fibrils

Angewandte Chemie - International Edition

Volumn 50, Issue 12, 2011, Pages 2837-2840

  Scheidt, Holger A ^a,c   Morgado, Isabel ^c   Rothemund, Sven ^b   Huster, Daniel ^a   Fändrich, Marcus ^d  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b UNIVERSITY HOSPITAL LEIPZIG   (Germany)

^c MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^d MAX PLANCK RESEARCH UNIT FOR ENZYMOLOGY OF PROTEIN FOLDING   (Germany)

Author keywords

Alzheimer; amyloid beta peptide; fibrous proteins; NMR spectroscopy; protofibrils

Indexed keywords

ALZHEIMER; AMYLOID BETAS; FIBROUS PROTEINS; NMR SPECTROSCOPY; PROTOFIBRILS;

GLYCOPROTEINS; PEPTIDES; SOLID STATE PHYSICS;

NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

AMYLOID; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA-PROTEIN (1-42); PEPTIDE FRAGMENT;

ALZHEIMER DISEASE; ARTICLE; CHEMISTRY; HUMAN; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN SECONDARY STRUCTURE; ULTRASTRUCTURE;

ALZHEIMER DISEASE; AMYLOID; AMYLOID BETA-PEPTIDES; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, SECONDARY;

EID: 79952498441     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201007265     Document Type: Article

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