Performance and attributes of liquid chromatography-mass spectrometry with targeted charge separation in quantitative analysis of therapeutic peptides

Journal of the American Society for Mass Spectrometry

Volumn 22, Issue 1, 2011, Pages 67-74

  Hao, Changtong ^a   Campbell, J Larry ^b   Verkerk, Udo H ^a   Le Blanc, J C Yves ^b   Siu, K W Michael ^a  

^a YORK UNIVERSITY   (Canada)

^b MDS SCIEX   (Canada)

Author keywords

High throughput quantification; Linear ion trap mass spectrometry; Quantification; Selected reaction monitoring; Therapeutic peptides; Trapped ion charge discrimination

Indexed keywords

HIGH-THROUGHPUT; LINEAR ION TRAP MASS SPECTROMETRY; QUANTIFICATION; SELECTED REACTION MONITORING; THERAPEUTIC PEPTIDES; TRAPPED ION;

AMINO ACIDS; ELECTRON TRAPS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; PEPTIDES; THROUGHPUT;

IONS;

ANGIOTENSIN I; ANGIOTENSIN II; ARGIPRESSIN; DYNORPHIN A; EXENDIN 4; INSULIN; KETOCONAZOLE; MELITTIN;

ACCURACY; AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; INTERMETHOD COMPARISON; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PEPTIDE ANALYSIS; PROCESS OPTIMIZATION; QUANTITATIVE ANALYSIS; SEPARATION TECHNIQUE;

ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; BEES; CHROMATOGRAPHY, LIQUID; HUMANS; MASS SPECTROMETRY; NEUROPEPTIDES; PEPTIDE HORMONES; REPRODUCIBILITY OF RESULTS; SWINE;

EID: 79952492279     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-010-0015-6     Document Type: Article

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