The cystic fibrosis F508del mutation in Crohn's disease

Journal of Cystic Fibrosis

Volumn 10, Issue 2, 2011, Pages 132-

  Bresso, Francesca ^a   D'Amato, Mauro ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSMEMBRANE CONDUCTANCE REGULATOR;

CROHN DISEASE; CYSTIC FIBROSIS; GENE MUTATION; HETEROZYGOSITY; INTESTINE INJURY; LETTER; RISK FACTOR;

CROHN DISEASE; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HUMANS; POINT MUTATION; RISK FACTORS;

EID: 79952455153     PISSN: 15691993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcf.2010.10.006     Document Type: Letter

References (5)

1. Bahmanyar S., Ekbom A., Askling J., Johannesson M., Montgomery S.M. Cystic fibrosis gene mutations and gastrointestinal diseases. J Cyst Fibros 2010, 9:288-291.
2. Bresso F., Askling J., Astegiano M., et al. Potential role for the common cystic fibrosis DeltaF508 mutation in Crohn's disease. Inflamm Bowel Dis 2007, 13:531-536.
3. Schroeder T.H., Lee M.M., Yacono P.W., et al. CFTR is a pattern recognition molecule that extracts Pseudomonas aeruginosa LPS from the outer membrane into epithelial cells and activates NF-kappa B translocation. Proc Natl Acad Sci USA 2002, 99:6907-6912.
4. Pier G.B., Grout M., Zaidi T., et al. Salmonella typhi uses CFTR to enter intestinal epithelial cells. Nature 1998, 393:79-82.
5. Eckburg P.B., Bik E.M., Bernstein C.N., et al. Diversity of the human intestinal microbial flora. Science 2005, 308:1635-1638.