Effects of the known pathogenic mutations on the aggregation pathway of the amyloidogenic peptide of apolipoprotein A-I

Journal of Molecular Biology

Volumn 407, Issue 3, 2011, Pages 465-476

  Raimondi, Sara ^a,b   Guglielmi, Fulvio ^c   Giorgetti, Sofia ^a   Gaetano, Sonia Di ^d   Arciello, Angela ^c   Monti, Daria M ^c   Relini, Annalisa ^e,f   Nichino, Daniela ^e   Doglia, Silvia M ^g   Natalello, Antonino ^g   Pucci, Piero ^c,f   Mangione, Palma ^a   Obici, Laura ^b   Merlini, Giampaolo ^a,b   Stoppini, Monica ^a,f   Robustelli, Paul ^h   Tartaglia, Gian Gaetano ⁱ   Vendruscolo, Michele ^h   Dobson, Christopher M ^h   Piccoli, Renata ^c,f   Bellotti, Vittorio ^a,b,f   more..

^a UNIVERSITY OF PAVIA   (Italy)

^b FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^d CNR   (Italy)

^e UNIVERSITY OF GENOA   (Italy)

^f NATIONAL INSTITUTE OF BIOSTRUCTURES AND BIOSYSTEMS   (Italy)

^g UNIVERSITY OF MILANO BICOCCA   (Italy)

^h UNIVERSITY OF CAMBRIDGE   (United Kingdom)

ⁱ CENTRE FOR GENOMIC REGULATION CRG   (Spain)

Author keywords

1 93 region of apolipoprotein A I; 1 93 ApoA I; AFM; ApoA I; apolipoprotein A I; atomic force microscopy; ATR; attenuated total reflection; CD; circular dichroism; Fourier transform infrared spectroscopy; FTIR; glutathione S transferase; GST; mass spectrometry; MS

Indexed keywords

APOLIPOPROTEIN A1;

ACIDIFICATION; AMINO TERMINAL SEQUENCE; ARTICLE; DISEASE SEVERITY; HUMAN; IN VIVO STUDY; MOLECULAR PATHOLOGY; MUTATION; PH; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN SECRETION; PROTEIN STRUCTURE; WILD TYPE;

AMYLOID; APOLIPOPROTEIN A-I; CIRCULAR DICHROISM; HUMANS; MODELS, MOLECULAR; MUTATION; PEPTIDES; PROTEIN CONFORMATION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 79952451835     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2011.01.044     Document Type: Article

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