Expression of perforin-granzyme pathway genes in the bursa of infectious bursal disease virus-infected chickens

Developmental and Comparative Immunology

Volumn 35, Issue 5, 2011, Pages 620-627

  Rauf, Abdul ^a,b   Khatri, Mahesh ^a   Murgia, Maria V ^a,b   Saif, Yehia M ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

Cytotoxic T cells; Granzyme; IBDV; Perforin; Virus clearance

Indexed keywords

GAMMA INTERFERON; GRANZYME A; HIGH MOBILITY GROUP PROTEIN; INTERLEUKIN 2; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PERFORIN;

ANIMAL TISSUE; ARTICLE; BURSA FABRICII; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHICKEN; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DOWN REGULATION; GENE EXPRESSION; INFECTIOUS BURSAL DISEASE; LYMPHOCYTIC INFILTRATION; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; TH1 CELL; UPREGULATION; VIRUS IMMUNITY;

GALLUS GALLUS; INFECTIOUS BURSAL DISEASE VIRUS;

EID: 79952451175     PISSN: 0145305X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dci.2011.01.007     Document Type: Article

References (44)

1. Abdel-Alim G.A., Saif Y.M. Detection and persistence of infectious bursal disease virus in specific-pathogen-free and commercial broiler chickens. Avian Dis. 2001, 45:646-654.
2. Abdel-Alim G.A., Saif Y.M. Immunogenicity and antigenicity of very virulent strains of infectious bursal disease viruses. Avian Dis. 2001, 45:92-101.
3. Appay V., Zaunders J.J., Papagno L., Sutton J., Jaramillo A., Waters A., Easterbrook P., Grey P., Smith D., McMichael A.J., Cooper D.A., Rowland-Jones S.L., Kelleher A.D. Characterization of CD4(+) CTLs ex vivo. J. Immunol. 2002, 168:5954-5958.
4. Brewer L., LaRue R., Hering B., Brown C., Njenga M.K. Transplanting encephalomyocarditis virus-infected porcine islet cells reverses diabetes in recipient mice but also transmits the virus. Xenotransplantation 2004, 11:160-170.
5. Christensen J.P., Cardin R.D., Branum K.C., Doherty P.C. CD4(+) T cell-mediated control of a gamma-herpesvirus in B cell-deficient mice is mediated by IFN-gamma. Proc. Natl. Acad. Sci. U.S.A. 1999, 96:5135-5140.
6. Dobbs M.E., Strasser J.E., Chu C.F., Chalk C., Milligan G.N. Clearance of herpes simplex virus type 2 by CD8+ T cells requires gamma interferon and either perforin- or Fas-mediated cytolytic mechanisms. J. Virol. 2005, 79:14546-14554.
7. Eldaghayes I., Rothwell L., Williams A., Withers D., Balu S., Davison F., Kaiser P. Infectious bursal disease virus: strains that differ in virulence differentially modulate the innate immune response to infection in the chicken bursa. Viral Immunol. 2006, 19:83-91.
8. Epple H.J., Allers K., Troger H., Kuhl A., Erben U., Fromm M., Zeitz M., Loddenkemper C., Schulzke J.D., Schneider T. Acute HIV infection induces mucosal infiltration with CD4+ and CD8+ T cells, epithelial apoptosis, and a mucosal barrier defect. Gastroenterology 2010, 139:1289-1300.
9. Giulietti A., Overbergh L., Valckx D., Decallonne B., Bouillon R., Mathieu C. An overview of real-time quantitative PCR: applications to quantify cytokine gene expression. Methods 2001, 25:386-401.
10. Haq K., Abdul-Careem M.F., Shanmuganthan S., Thanthrige-Don N., Read L.R., Sharif S. Vaccine-induced host responses against very virulent Marek's disease virus infection in the lungs of chickens. Vaccine 2010, 28:5565-5572.
11. Heller K.N., Gurer C., Munz C. Virus-specific CD4+ T cells: ready for direct attack. J. Exp. Med. 2006, 203:805-808.
12. Hersperger A.R., Pereyra F., Nason M., Demers K., Sheth P., Shin L.Y., Kovacs C.M., Rodriguez B., Sieg S.F., Teixeira-Johnson L., Gudonis D., Goepfert P.A., Lederman M.M., Frank I., Makedonas G., Kaul R., Walker B.D., Betts M.R. Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control. PLoS Pathog. 2010, 6:e1000917.
13. Ishikawa H., Tanaka K., Kutsukake E., Fukui T., Sasaki H., Hata A., Noda S., Matsumoto T. IFN-gamma production downstream of NKT cell activation in mice infected with influenza virus enhances the cytolytic activities of both NK cells and viral antigen-specific CD8+ T cells. Virology 2010, 407:325-332.
14. Khatri M., Palmquist J.M., Cha R.M., Sharma J.M. Infection and activation of bursal macrophages by virulent infectious bursal disease virus. Virus Res. 2005, 113:44-50.
15. Kim I.J., You S.K., Kim H., Yeh H.Y., Sharma J.M. Characteristics of bursal T lymphocytes induced by infectious bursal disease virus. J. Virol. 2000, 74:8884-8892.
16. Kuerten S., Nowacki T.M., Kleen T.O., Asaad R.J., Lehmann P.V., Tary-Lehmann M. Dissociated production of perforin, granzyme B, and IFN-gamma by HIV-specific CD8(+) cells in HIV infection. AIDS Res. Hum. Retroviruses 2008, 24:62-71.
17. Kumar P.A., Das S.K., Rao J.R. Effect of immunostimulation on cytotoxic activity of intestinal intraepithelial lymphocytes of chickens in infectious bursal disease and Eimeria tenella infections. Acta Vet. Hung. 1998, 46:1-11.
18. Lichtenheld M.G., Podack E.R. Structure of the human perforin gene. A simple gene organization with interesting potential regulatory sequences. J. Immunol. 1989, 143:4267-4274.
19. Meier W.A., Galeota J., Osorio F.A., Husmann R.J., Schnitzlein W.M., Zuckermann F.A. Gradual development of the interferon-gamma response of swine to porcine reproductive and respiratory syndrome virus infection or vaccination. Virology 2003, 309:18-31.
20. Misko I.S., Pope J.H., Hutter R., Soszynski T.D., Kane R.G. HLA-DR-antigen-associated restriction of EBV-specific cytotoxic T-cell colonies. Int. J. Cancer 1984, 33:239-243.
21. Mok C.K., Lee D.C., Cheung C.Y., Peiris M., Lau A.S. Differential onset of apoptosis in influenza A virus H5N1- and H1N1-infected human blood macrophages. J. Gen. Virol. 2007, 88:1275-1280.
22. Mullbacher A., Waring P., Tha Hla R., Tran T., Chin S., Stehle T., Museteanu C., Simon M.M. Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes. Proc. Natl. Acad. Sci. U.S.A. 1999, 96:13950-13955.
23. Nagata S., Golstein P. The Fas death factor. Science 1995, 267:1449-1456.
24. Nargi-Aizenman J.L., Simbulan-Rosenthal C.M., Kelly T.A., Smulson M.E., Griffin D.E. Rapid activation of poly(ADP-ribose) polymerase contributes to Sindbis virus and staurosporine-induced apoptotic cell death. Virology 2002, 293:164-171.
25. Palmquist J.M., Khatri M., Cha R.M., Goddeeris B.M., Walcheck B., Sharma J.M. In vivo activation of chicken macrophages by infectious bursal disease virus. Viral Immunol. 2006, 19:305-315.
26. Pedrini M., Grunicke H., Csordas A. Tissue-specific pattern of nonhistone high mobility group proteins in various organs of the chicken. Electrophoresis 1992, 13:397-399.
27. Pertile T.L., Sharma J.M., Walser M.M. Reovirus infection in chickens primes splenic adherent macrophages to produce nitric oxide in response to T cell-produced factors. Cell Immunol. 1995, 164:207-216.
28. Peters M.A., Lin T.L., Wu C.C. Real-time RT-PCR differentiation and quantitation of infectious bursal disease virus strains using dual-labeled fluorescent probes. J. Virol. Methods 2005, 127:87-95.
29. Pinkoski M.J., Green D.R. Granzyme A: the road less traveled. Nat. Immunol. 2003, 4:106-108.
30. Rautenschlein S., Haase C. Differences in the immunopathogenesis of infectious bursal disease virus (IBDV) following in ovo and post-hatch vaccination of chickens. Vet. Immunol. Immunopathol. 2005, 106:139-150.
31. Rautenschlein S., Yeh H.Y., Sharma J.M. The role of T cells in protection by an inactivated infectious bursal disease virus vaccine. Vet. Immunol. Immunopathol. 2002, 89:159-167.
32. Salcedo T.W., Azzoni L., Wolf S.F., Perussia B. Modulation of perforin and granzyme messenger RNA expression in human natural killer cells. J. Immunol. 1993, 151:2511-2520.
33. Sarin A., Williams M.S., Alexander-Miller M.A., Berzofsky J.A., Zacharchuk C.M., Henkart P.A. Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases. Immunity 1997, 6:209-215.
34. Sarson A.J., Abdul-Careem M.F., Read L.R., Brisbin J.T., Sharif S. Expression of cytotoxicity-associated genes in Marek's disease virus-infected chickens. Viral Immunol. 2008, 21:267-272.
35. Sharma J.M., Kim I.J., Rautenschlein S., Yeh H.Y. Infectious bursal disease virus of chickens: pathogenesis and immunosuppression. Dev. Comp. Immunol. 2000, 24:223-235.
36. Sharma J.M., Lee L.F. Effect of infectious bursal disease on natural killer cell activity and mitogenic response of chicken lymphoid cells: role of adherent cells in cellular immune suppression. Infect. Immun. 1983, 42:747-754.
37. Smyth M.J., Trapani J.A. Granzymes: exogenous proteinases that induce target cell apoptosis. Immunol. Today 1995, 16:202-206.
38. Tanimura N., Sharma J.M. Appearance of T cells in the bursa of Fabricius and cecal tonsils during the acute phase of infectious bursal disease virus infection in chickens. Avian Dis. 1997, 41:638-645.
39. Trapani J.A., Jans D.A., Jans P.J., Smyth M.J., Browne K.A., Sutton V.R. Efficient nuclear targeting of granzyme B and the nuclear consequences of apoptosis induced by granzyme B and perforin are caspase-dependent, but cell death is caspase-independent. J. Biol. Chem. 1998, 273:27934-27938.
40. Trapani J.A., Smyth M.J. Functional significance of the perforin/granzyme cell death pathway. Nat. Rev. Immunol. 2002, 2:735-747.
41. Van Parijs L., Abbas A.K. Role of Fas-mediated cell death in the regulation of immune responses. Curr. Opin. Immunol. 1996, 8:355-361.
42. Wahid R., Cannon M.J., Chow M. Virus-specific CD4+ and CD8+ cytotoxic T-cell responses and long-term T-cell memory in individuals vaccinated against polio. J. Virol. 2005, 79:5988-5995.
43. Yeh H.Y., Rautenschlein S., Sharma J.M. Protective immunity against infectious bursal disease virus in chickens in the absence of virus-specific antibodies. Vet. Immunol. Immunopathol. 2002, 89:149-158.
44. Yuan L., Wen K., Azevedo M.S., Gonzalez A.M., Zhang W., Saif L.J. Virus-specific intestinal IFN-gamma producing T cell responses induced by human rotavirus infection and vaccines are correlated with protection against rotavirus diarrhea in gnotobiotic pigs. Vaccine 2008, 26:3322-3331.