KPC-2 Carbapenemase-producing Klebsiella pneumoniae isolates from patients with Cystic Fibrosis

Journal of Cystic Fibrosis

Volumn 10, Issue 2, 2011, Pages 140-142

  Leão, Robson S ^a   Pereira, Rosana H V ^a   Folescu, Tânia W ^b   Albano, Rodolpho M ^c   Santos, Erica A ^d   Junior, Luiz G C ^a   Marques, Elizabeth A ^a,b,c,d  

^a UNIVERSIDADE DO ESTADO DO RIO DE JANEIRO   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^d HOSPITAL UNIVERSITÁRIO PEDRO ERNESTO   (Brazil)

Author keywords

Carbapenemases; Cystic Fibrosis; Klebsiella pneumoniae; KPC

Indexed keywords

AMIKACIN; AZITHROMYCIN; AZTREONAM; BRONCHODILATING AGENT; CARBAPENEMASE; CEFEPIME; CEFOTAXIME; CEFTAZIDIME; CIPROFLOXACIN; COLISTIN; DORNASE ALFA; ERTAPENEM; GENTAMICIN; IMIPENEM; MEROPENEM; OXACILLIN; PANCREAS ENZYME; SULTAMICILLIN; TOBRAMYCIN; VITAMIN;

ADOLESCENT; ADULT; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL COLONIZATION; BACTERIUM ISOLATE; CASE REPORT; CYSTIC FIBROSIS; DISK DIFFUSION; FEMALE; HUMAN; KLEBSIELLA INFECTION; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN;

ADOLESCENT; BACTERIAL PROTEINS; BETA-LACTAMASES; CYSTIC FIBROSIS; FEMALE; HUMANS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; YOUNG ADULT;

EID: 79952450316     PISSN: 15691993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcf.2010.12.003     Document Type: Article

References (20)

1. Lipuma J.J. The changing microbial epidemiology in cystic fibrosis. Clin Microbiol Rev 2010, 23:299-323.
2. Cai J., Zhou C.H.W., Zhang R., Chen G.X. Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli isolates possessing the plasmid-mediated carbapenem-hydrolyzing β-lactamase KPC-2 in intensive care units of a Chinese hospital. Antimicrob Agents Chemother 2008, 52:2014-2018.
3. Leavitt A., Chmelnitsky I., Ofek I., Carmeli Y., Navon-Venezia S. Plasmid pKpQIL encoding KPC-3 and TEM-1 confers carbapenem resitance in an extremely drug-resistant epidemic Klebsiella pneumoniae strain. J Antimicrob Chemother 2010, 5:243-248.
4. Maltezou H., Giakkoupi P., Maragos A., Bolikas M., Raftopoulos V., Papahatzaki H., et al. Outbreak of infections due to KPC-2-producing Klebsiella pneumoniae in a hospital in Crete (Greece). J Infect 2009, 8:213-219.
5. Nordmann P., Cuzon G., Naas T. The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria. Lancet Infect Dis 2009, 9:228-236.
6. Leão R.S., Carvalho-Assef A.P.D'.A., Correal J.C.D., Silva R.V., Goldemberg D.C., Asensi M.D., et al. KPC-2 producing Klebsiella pneumoniae and Escherichia coli co-infection in a catheter related infection. Clin Microbiol Infect 2010, [Epub ahead of print].
7. Monteiro J., Santos A.F., Asensi M.D., Peirano G., Gales A.C. First report of KPC-2-producing Klebsiella pneumoniae strains in Brazil. Antimicrob Agents Chemother 2009, 53:333-334.
8. Pavez M., Mamizuka E.M., Lincopan N. Early dissemination of KPC-2-producing Klebsiella pneumoniae strains in Brazil. Antimicrob Agents Chemother 2009, 53:2702.
9. Peirano G., Seki L.M., Val Passos V.L., Pinto M.C.F.G., Guerra L.R., Asensi M.D. Carbapenemhydrolysing β-lactamase KPC-2 in Klebsiella pneumoniae isolated in Rio de Janeiro, Brazil. J Antimicrob Chemother 2009, 63:265-268.
10. Pournaras S., Protonotariou E., Voulgari E., Kristo I., Dimitroulia E., Vitti D., et al. Clonal spread of KPC-2 carbapenemase-producing Klebsiella pneumoniae strains in Greece. J Antimicrob Chemother 2009, 64:348-352.
11. Kontopoulou K., Protonotariou E., Vasilakos K., Kriti M., Koteli A., Antoniadou E., et al. Hospital outbreak caused by Klebsiella pneumoniae producing KPC-2 beta-lactamase resistant to colistin. Hosp Infect 2010, 76:70-73.
12. CLSI Performance Standards for Antimicrobial Susceptibility Testing; Twentieth Information Supplement (June 2010 Update). CLSI. M100-S20-U 2010, Clinical and Laboratory Standards Institute, Wayne, PA.
13. Anderson K.F., Lonsway D.R., Rasheed J.K., Biddle J., Jensen B., McDougal L.K., et al. Evaluation of methods to identify the Klebsiella pneumoniae carbapenemase in Enterobacteriaceae. J Clin Microbiol 2007, 45:2723-2725.
14. Otto T.D., Vasconcellos E.A., Gomes L.H.F., Moreira A.S., Degrave W.M., Mendonça-Lima L., et al. ChromaPipe: a pipeline for analysis, quality control and management for a DNA sequencing facility. Genet Mol Res 2008, 7:861-871.
15. Zavascki A.P., Goldani L.Z., Li J., Nation R.L. Polymyxin B for the treatment of multidrug-resistant pathogens: a critical review. J Antimicrob Chemother 2007, 60:1206-1215.
16. Naas T., Cuzon G., Villegas M.V., Lartigue M.F., Quinn J.P., Nordmann V. Genetic structures at the origin of acquisition of the β-lactamase blaKPC gene. Antimicrob Agents Chemother 2008, 52:1257-1263.
17. Akpaka P.E., Swanston W.H., Ihemere H.N., Correa A., Torres J.A., Tafur J.D., et al. Emergence of KPC producing Pseudomonas aeruginosa in Trinidad and Tobago. J Clin Microbiol 2009, 47:2670-2671.
18. Poirel L., Nordmann P., Lagrutta E., Cleary T., Munoz-Price L.S. Emergence of KPC-producing Pseudomonas aeruginosa in the United States. Antimicrob Agents Chemother 2010, 54:3072.
19. Wolter D.J., Khalaf N.I., Robledo E., Vázquez G.J., Santé M.I., Aquino E.E., et al. Surveillance of carbapenem resistant Pseudomonas aeruginosa isolates from Puerto Rican Medical Center Hospitals: dissemination of KPC and IMP-18 b-lactamases. Antimicrob Agents Chemother 2009, 53:1660-1664.
20. Cheng K., Smyth R.L., Govan J.R.W., Doherty C., Winstanley C., Denning N., et al. Spread of β-lactam-resistant Pseudomonas aeruginosa in a cystic fibrosis clinic. Lancet 1996, 348:639-642.