Asymmetric synthesis of 1-substituted 1,2,3,4-tetrahydropyrrolo[1,2-a] pyrazines

Synthesis

Volumn , Issue 6, 2011, Pages 909-918

  Gualandi, Andrea ^a   Cerisoli, Lucia ^a   Monari, Magda ^a   Savoia, Diego ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

asymmetric synthesis; diastereoselectivity; Grignard reagents; heterocycles; oxazolidines; tetrahydropyrrolopyrazines

Indexed keywords

ORGANOMETALLICS;

ASYMMETRIC SYNTHESIS; DIASTEREO-SELECTIVITY; GRIGNARD REAGENT; HETEROCYCLES; OXAZOLIDINES; TETRAHYDROPYRROLOPYRAZINES;

STEREOSELECTIVITY;

1 (2 BROMOETHYL) 1H PYRROLE 2 CARBALDEHYDE; 1 (2 CHLOROETHYL) 1H PYRROLE 2 CARBALDEHYDE; 1 ETHYL 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRAZINE; 1 METHYL 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRAZINE; 1,2,3,4 TETRAHYDROPYRROL[1,2 A]PYRAZINE DERIVATIVE; 2 PHENYL 2 [1 PHENYL 3,4 DIHYDROPYRROLO[1,2 A]PYRAZIN 2(1H) YL] 2 PHENYLETHANOL; 2 [1 ALLYL 3,4 DIHYDROPYRROLO[1,2 A]PYRAZIN 2(1H) YL] 2 PHENYLETHANOL; 2 [1 BENZYL 3,4 DIHYDROPYRROLOL[1,2 A]PYRAZIN 2(1H) YL] 2 PHENYLETHANOL; 2 [1 BENZYL 3,4 DIHYDROPYRROLO[1,2 A]PYRAZIN 2(1H) YL] 3 METHYLBUTAN 1 OL; 2 [1 ETHYL 3,4 DIHYDROPYRROLO[1,2 A]PYRAZIN 2 (1H) YL] 2 PHENYLETHANOL; 2 [1 ETHYL 3,4 DIHYDROPYRROLO[1,2 A]PYRAZIN 2(1H) YL] 3 METHYLBUTAN 1 OL; 2 [1 HEXYL 3,4 DIHYDROPYRROLO[1,2 A]PYRAZIN 2(1H) YL] 2 PHENYLETHANOL; 2 [1 METHYL 3,4 DIHYDROPYRROLO[1,2 A]PYRAZIN 2(1H) YL] 2 PHENYLETHANOL; 2 [2 HYDROXY 1 PHENYLETHYL] 3,4 DIHYDROPYRROLO[1,2 A]PYRAZIN 2 IUM BROMIDE; 3 ISOPROPYL 2,3,6 TETRAHYDRO 10B H [1,3]OXAZOLO[3,2 A]PYRROLO[2,1 C]PYRAZINE; 3 METHY 2 [1 PHENYL 3,4 DIHYDROPYRROLO[1,2 A]PYRAZIN 2(1H) YL]BUTAN 1 OL; 3 METHYL 2 [1 METHYL 3,4 DIHYDROPYRROLO[1,2 A]PYRAZIN 2(1H) YL]BUTAN 1 OL; 3 PHENYL 2,3,5,6 TETRAHYDRO 10B H [1,3]OXAZOLO[3,2 A]PYRROLO[2,1 C]PYRAZINE; PYRAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; COVALENT BOND; STEREOCHEMISTRY; SYNTHESIS; TEMPERATURE;

EID: 79952445780     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0030-1258436     Document Type: Article

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