Novel routes to 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazines and 5,6,9,10,11,11a-hexahydro-8H-pyrido[1,2-a]pyrrolo[2,1-c]pyrazines

Journal of Organic Chemistry

Volumn 67, Issue 23, 2002, Pages 8220-8223

  Katritzky, Alan R ^a   Jain, Ritu ^a   Xu, Yong Jiang ^a   Steel, Peter J ^b  

^a University of Florida ^*  (United States)

^b UNIVERSITY OF CANTERBURY   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

INTERMEDIATES;

CONDENSATION; SODIUM COMPOUNDS; SUBSTITUTION REACTIONS;

AROMATIC COMPOUNDS;

1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRAZINE DERIVATIVE; 5,6,9,10,11A HEXAHYDRO 8H PYRIDO[1,2 A]PYRROLO[2,1 C]PYRAZINE DERIVATIVE; ALDOSE REDUCTASE INHIBITOR; ANTIHYPERTENSIVE AGENT; BENZOTRIAZOLE DERIVATIVE; ETHYLAMINE; FORMALDEHYDE; GLUTARALDEHYDE; PSYCHOTROPIC AGENT; PYRAZINE DERIVATIVE; SODIUM BOROHYDRIDE; SODIUM CYANIDE; UNCLASSIFIED DRUG; BENZOTRIAZOLE; PYRROLIDINE DERIVATIVE; TRIAZOLE DERIVATIVE;

ARTICLE; DRUG ACTIVITY; DRUG SYNTHESIS; HYDROGENATION; POLYMERIZATION; REACTION ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; STEREOISOMERISM; SYNTHESIS;

MOLECULAR STRUCTURE; PYRAZINES; PYRROLIDINES; STEREOISOMERISM; TRIAZOLES;

EID: 0037111698     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo020371t     Document Type: Article

References (18)

1. Seredenin, S. B.; Voronina, T. A.; Beshimov, A.; Peresada, V. P.; Likhosherstov, A. M. RU 2,099,055, 1997; Chem. Abstr. 1998, 128, 290245j.
2. Seredenin, S. B.; Voronina, T. A.; Likhosherstov, A. M.; Peresada, V. P.; Molodavkin, G. M.; Halikas, J. A. US 5,378,846, 1995; Chem. Abstr. 1995, 123, 83350w.
3. Peresada, V. P.; Medvedev, O. S.; Likhosherstov, A. M.; Skoldinov, A. P.Khim.-Farm. Zh. 1987, 21, 1054; Chem. Abstr. 1988, 108, 68298g.
4. Peresada, V. P.; Medvedev, O. S.; Likhosherstov, A. M.; Skoldinov, A. P.Khim.-Farm. Zh. 1987, 21, 1054; Chem. Abstr. 1988, 108, 68298g.
5. Negoro, T.; Murata, M.; Ueda, S.; Fujitani, B.; Ono, Y.; Kuromiya, A.; Komiya, M.; Suzuki, K.; Matsumoto, J.-I. J. Med. Chem. 1998, 41, 4118.
6. Blum, C.; Hutchison, A. US 5,668,283, 1997; Chem. Abstr. 1997, 127, 293247b.
7. Skoldinov, A. P.; Likhosherstov, A. M.; Peresada, V. P. Brit. UK Pat. Appl. 2,025,936, 1980; Chem Abstr. 1981, 93, 186406k.
8. Skoldinov, A. P.; Likhosherstov, A. M.; Peresada, V. P. Ger. Offen. 2,832,488, 1980; Chem. Abstr. 1980, 93, 46720h.
9. Skoldinov, A. P.; Likhosherstov, A. M.; Peresada, V. P. USSR 798,104, 1981; Chem. Abstr. 1981, 95, 7337k.
10. Katritzky, A. R.; Lan, X.; Yang, J. Z.; Denisko, O. V. Chem. Rev. 1998, 98, 409.
11. Katritzky, A. R.; Qi, M. Tetrahedron Lett. 1998, 54, 2647.
12. Katritzky, A. R.; Qi, M. Collect. Czech. Chem. Commun. 1998, 63, 599.
13. Katritzky, A. R.; Belyakov, S. A. Aldrichimica Acta 1998, 31, 35.
14. Katritzky, A. R.; Li, J.; Xie, L. Tetrahedron 1999, 55, 8263.
15. Katritzky, A. R.; Denisko, O. V. Pure Appl. Chem. 2000, 72, 1597.
16. de Pablo, M. S.; Gandásegui, T., Vaquero, J. J.; Navìo, J. L. G.; Alvarez-Builla, J. Tetrahedron 1992, 48, 8793.
17. Katritzky, A. R.; Xu, Y.-J.; He, H.-Y.; Mehta, S. J. Org. Chem. 2001, 66, 5590.
18. Katritzky, A. R.; Xu, Y.-J.; He, H.-Y. J. Chem. Soc., Perkin Trans. 1 2002, 592.