Effect of osmolytes on protein dynamics in the lactate dehydrogenase- catalyzed reaction

Biochemistry

Volumn 50, Issue 10, 2011, Pages 1582-1589

  Zhadin, Nickolay ^a   Callender, Robert ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ARRHENIUS; BINDING RATE; CATALYZED REACTIONS; CHEMICAL EVENTS; ENERGY LANDSCAPE; HIGHER TEMPERATURES; HYDRIDE TRANSFERS; LACTATE DEHYDROGENASE; LASER INDUCED; LOOP CLOSURE; MICROSCOPIC RATE CONSTANTS; NADH FLUORESCENCE; OPEN LOOPS; OSMOLYTES; PROTEIN COMPLEXES; PROTEIN DYNAMICS; PROTEIN ENSEMBLES; PYRUVATES; REACTION SYSTEM; RELAXATION KINETICS; TEMPERATURE DEPENDENCE; TRIMETHYLAMINE N OXIDES;

BINDING ENERGY; CATALYSIS; CONFORMATIONS; ENTHALPY; METABOLISM; PROTEINS; RATE CONSTANTS; REACTION KINETICS; SPECTROSCOPY; TEMPERATURE; THERMODYNAMICS; UREA;

ACTIVATION ENERGY;

LACTATE DEHYDROGENASE; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; TRIMETHYLAMINE OXIDE; UREA;

ABSORPTION; ARTICLE; CATALYSIS; CONCENTRATION (PARAMETERS); ENTHALPY; ENZYME SUBSTRATE COMPLEX; FLUORESCENCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STABILITY; QUALITATIVE ANALYSIS; TEMPERATURE DEPENDENCE; THERMODYNAMICS;

ANIMALS; BIOCATALYSIS; L-LACTATE DEHYDROGENASE; OSMOSIS; SWINE; THERMODYNAMICS;

EID: 79952421282     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi1018545     Document Type: Article

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