Inhibition of the diclofenac-induced cyclooxygenase-2 activity by paracetamol in cultured macrophages is not related to the intracellular lipid hydroperoxide tone

Fundamental and Clinical Pharmacology

Volumn 25, Issue 2, 2011, Pages 186-190

  Ayoub, Samir S ^a   Joshi, Amrish ^a   Chol, Mary ^a   Gilroy, Derek W ^b   Seed, Michael P ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Cyclooxygenase 2; Diclofenac; Lipid hydroperoxide; Lipopolysaccharide; Paracetamol; T butyl hydroperoxide

Indexed keywords

CYCLOOXYGENASE 2; DICLOFENAC; PARACETAMOL; TERT BUTYL HYDROPEROXIDE;

ARTICLE; CELL STIMULATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; MACROPHAGE; PRIORITY JOURNAL;

ACETAMINOPHEN; ANIMALS; CELL LINE; CYCLOOXYGENASE 2; CYCLOOXYGENASE INHIBITORS; DICLOFENAC; DRUG INTERACTIONS; ENZYME INDUCTION; LIPID PEROXIDES; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE;

EID: 79952400948     PISSN: 07673981     EISSN: 14728206     Source Type: Journal    
DOI: 10.1111/j.1472-8206.2010.00842.x     Document Type: Article

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