Soluble transferrin receptor as a diagnostic laboratory test for detection of iron deficiency anemia in acute illness of hospitalized patients

Israel Medical Association Journal

Volumn 13, Issue 2, 2011, Pages 96-98

  Berlin, Tatiana ^a,b   Meyer, Avraham ^a,b   Rotman Pikielny, Pnina ^a,b   Natur, Aiman ^a,b   Levy, Yair ^a,b  

^a MEIR MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

Ferritin; Gastrointestinal bleeding; Iron defieciency anemia; Soluble transferin receptor

Indexed keywords

BIOLOGICAL MARKER; FERRITIN; TRANSFERRIN RECEPTOR;

ACUTE DISEASE; AGED; ANGIODYSPLASIA; ARTICLE; ATROPHIC GASTRITIS; CLINICAL ARTICLE; COLITIS; COLON CARCINOMA; COLON POLYP; COLONOSCOPY; DIAGNOSTIC TEST; DUODENUM ULCER; EROSIVE GASTRITIS; ESOPHAGOGASTRODUODENOSCOPY; FEMALE; HUMAN; IRON DEFICIENCY ANEMIA; MALE; RETROSPECTIVE STUDY; STOMACH CARCINOMA;

ACUTE DISEASE; AGED; ANEMIA, IRON-DEFICIENCY; FEMALE; GASTROINTESTINAL HEMORRHAGE; HOSPITALIZATION; HUMANS; MALE; MIDDLE AGED; RECEPTORS, TRANSFERRIN; RETROSPECTIVE STUDIES;

EID: 79952382052     PISSN: 15651088     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Rockey DC. Occult 1. gastrointestinal bleeding. Gastroenterol Clin North Am 2005; 34: 699-718.
2. Zandman-Goddard G, Shoenfeld Y. Hyperferritinemia in autoimmunity. IMAJ Isr Med Assoc J 2008; 10: 83-4.
3. Beguin Y. Soluble transferrin receptor for the evaluation of erythropoiesis and iron status. Clin Chim Acta 2003; 329: 9-22.
4. Das Gupta A, Abbi A. High serum transferrin receptor level in anemia of chronic disorders indicates coexistent iron deficiency. Am J Hematol 2003; 72: 158-61.
5. Baynes RD, Skikne BS, Cook JD. Circulating transferrin receptors and assessment of iron status. J Nutr Biochem 1994; 5: 322-30.
6. Baynes RD. Assessment of iron status. Clin Biochem 1996; 29: 209-15.
7. Ferguson BJ, Skikne BS, Simpson KM, Baynes RD, Cook JD. Serum transferrin receptor distinguishes the anemia of chronic disease from IDA. J Lab Clin Med 1992; 119: 385-90.
8. Cazzola M, Ponchio L, de Benedeti F, et al. Defective iron supply for erythropoiesis and adequate endogenous erythropoietin production in the anemia associated with systemic-onset juvenile chronic arthritis. Blood 1996; 87: 4824-30.
9. Punnonen K, Irjala K, Rajamaki A. Serum transferrin receptor and its ratio to serum ferritin in the diagnosis of iron deficiency. Blood 1997; 89: 1052-7.
10. Weiss G, Goodnough L. Anemia of chronic disease. N Engl J Med 2005; 352: 1011-23.
11. Beuin Y, Clemons G, Pootrakul P, Fillet G. Quantitative assessment of erythropoiesis and functional classification of anemia based on measurements of serum transferrin receptor and erythropoietin. Blood 1993; 81: 1067-76.
12. El Nawawy A, Massoud MN, El Bordiny M, Hegazy S. Evaluation of serum soluble transferrin receptors and erythropoietin levels as indicators for erythropoietic activity among multi-transfused beta-talassemic patients. J Trop Pediatr 2002; 48: 33-8.
13. Sighal A, Cook JD, Skikne BS, Thomas P, Sergeant B, Sergeant G. The clinical significance of serum transferrin receptor levels in sickle cell disease. Br J Haematol 1993; 84: 301-4.
14. Koistinen PO, Rusko H, Irjala K, et al. EPO, red cells, and serum transferrin receptor in continuous and intermittent hypoxia. Med Sci Sports Exers 2000; 32: 800-4.
15. Semba RD, Kumwenda N, Hoover DR, et al. Assessment of iron status using plasma transferrin receptor in pregnant women with and without human immunodeficiency virus infection in Malawi. Eur J Clin Nutr 2000; 54: 72-7.
16. Punnonen K, Irjala K, Rajamaki A. Serum transferrin receptor and its ratio to serum ferritin in the diagnosis of iron deficiency. Blood 1997; 89: 1052-7.
17. Martini A, Ravelli A, Di Fuccia G, Rosti V, Cazzola M, Barosi G. Intravenous iron therapy for severe anaemia in systemic-onset juvenile chronic arthritis. Lancet 1994; 344: 1052-4.
18. Remacha AF, Sarda MP, Parellada M, Ubeda J, Manteiga R. The role of serum transferrin receptor in the diagnosis of iron deficiency. Haematologica 1998; 83: 963-6.
19. Pettersson T, Kivivuori SM, Siimes MA. Is serum transferrin receptor useful for detecting iron-deficiency in anaemic patients with chronic inflammatory disease? Br J Rheumatol 1994; 33: 740-4.
20. Baillie FJ, Morrison AF, Fergus I. Soluble transferring receptor: a discriminating assay for iron deficiency. Clin Lab Haematol 2003; 25(6): 353-7.
21. Lee EJ, Oh EJ, Park YJ, Lee HK, Kim BK. Soluble transferrin receptor (sTfR), ferritin, and sTfR/log ferritin index in anemic patients with nonhematologic malignancy and chronic inflammation. Clin Chem 2002; 48: 1118-2