Bronchoalveolar lavage in the diagnosis of ventilator-associated pneumonia: To quantitate or not, that is the question

American Surgeon

Volumn 77, Issue 3, 2011, Pages 297-303

  Riaz, Omer J ^a   Malhotra, Ajai K ^a   Aboutanos, Michel B ^a   Duane, Therese M ^a   Goldberg, Aaron E ^a   Borchers, C Todd ^a   Martin, Nancy R ^a   Ivatury, Rao R ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METICILLIN; PIPERACILLIN PLUS TAZOBACTAM; VANCOMYCIN;

ARTICLE; BACTERIAL GROWTH; BACTERIUM CULTURE; BACTERIUM IDENTIFICATION; BRONCHOSCOPY; COLONY FORMING UNIT; CONTROLLED STUDY; CORYNEBACTERIUM; CULTURE TECHNIQUE; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; FEMALE; HUMAN; INTERMETHOD COMPARISON; LUNG LAVAGE; MAJOR CLINICAL STUDY; MALE; NONHUMAN; PREDICTION; PROSPECTIVE STUDY; PSEUDOMONAS; QUANTITATIVE DIAGNOSIS; SENSITIVITY AND SPECIFICITY; VENTILATOR ASSOCIATED PNEUMONIA;

ADULT; BACTERIAL INFECTIONS; BRONCHOALVEOLAR LAVAGE FLUID; BRONCHOSCOPY; COLONY COUNT, MICROBIAL; FEMALE; HUMANS; INTENSIVE CARE; MALE; MIDDLE AGED; PNEUMONIA, VENTILATOR-ASSOCIATED; PREDICTIVE VALUE OF TESTS;

EID: 79952379840     PISSN: 00031348     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Tablan OC, Anderson LJ, Besser R, et al; Healthcare Infection Control Practices Advisory Committee, Centers for Disease Control and Prevention. Guidelines for preventing health-care-associated pneumonia, 2003: recommendations of the CDC and the Healthcare Infection Control Practices Advisory Committee. MMWR Recomm Rep 2004;53:1-36.
2. Brown DL, Hungness DS, Campbell RS, et al. Ventilator associated pneumonia in the surgical intensive care unit. J Trauma 2001;51:1207-16. (Pubitemid 34028463)
3. McRitchie DI, Mathews JG, Fink MP. Pneumonia in patients with multiple trauma. Clin Chest Med 1995;16:135-46.
4. Rodriguez JL, Gibbons KJ, Bitzer LG, et al. Pneumonia: incidence, risk factors, and outcomes in injured patients. J Trauma 1991;31:907-14.
5. Niederman MS. Guidelines for the management of respiratory infection: why do we need them, how should they be developed, and can they be useful? Curr Opin Pulm Med 1996;2:161-5.
6. Craven DE, Kunches LM, Kilinsky V, et al. Risk factors for pneumonia and fatality in patients receiving continuous mechanical ventilation. Am Rev Respir Dis 1986;133:792-6. (Pubitemid 16116505)
7. Hutt E, Kramer AM. Evidence-based guidelines for management of nursing-home acquired pneumonia. J Fam Pract 2002;51:709-16. (Pubitemid 34851756)
8. American Thoracic SocietyGuidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia [consensus statement]. Am J Respir Care Med 2005;171:388-416.
9. Fagon JY, Chastre J, Hance AJ, et al. Evaluation of clinical judgement in the identification and treatment of nosocomial pneumonia in ventilated patients. Chest 1993;103:547-53. (Pubitemid 23070761)
10. Johanson WG, Pierce AK, Sanford JP, Thomas GD. Nosocomial respiratory infections with Gram-negative bacilli. The significance of colonization of the respiratory tract. Ann Intern Med 1972;77:701-6.
11. Marquette CH, Chopin MC, Wallet F, et al. Diagnostic test for pneumonia in ventilated patients: prospective evaluation of diagnostic accuracy using histology as a diagnostic gold standard. Am J Respir Crit Care Med 1995;151:1878-88.
12. Wermet D, Marquette CH, Chopin MC, et al. Influence of pulmonary bacteriology and histology on the yield of diagnostic procedures in ventilator-acquired pneumonia. Am J Respir Crit Care Med 1998;158:139-47.
13. Rouby JJ, Martin DL, Poete P, et al. Nosocomial bronchopneumonia in the critically ill: histologic and bacteriologic aspects. Am Rev Respir Dis 1992;146:1059-66.
14. Fagon JY, Chastre J, Wolff M, et al. Invasive and noninvasive strategies for management of suspected ventilator-associated pneumonia: a randomized trial. Ann Intern Med 2000;132:621-30. (Pubitemid 30217554)
15. Chastre J, Wolff M, Fagon JY, et al. Comparison of 8 vs 15 days of antibiotic therapy for ventilator-associated pneumonia in adults: a randomized trial. JAMA 2003;290:2588-98. (Pubitemid 37443289)
16. Heyland DK, Cook DJ, Marshall J, et al., Canadian Critical Care Trials Group. The clinical utility of invasive diagnostic techniques in the setting of ventilator-associated pneumonia. Chest 1999;115:1076-84.
17. Baker AM, Bowton DL, Haponik EF. Decision making in nosocomial pneumonia: an analytic approach to the quantitative bronchoscopic cultures. Chest 1995;107:85-95.
18. Heyland DK, Cook DJ, Dodek P, et al., Canadian Critical Care Trials Group. A randomized trial of diagnostic techniques for ventilator-associated pneumonia. N Engl J Med 2006;355:2619.
19. Wunderink RG, Woldenberg LS, Zeiss J, et al. The radiologic diagnosis of autopsy-proven ventilator-associated pneumonia. Chest 1992;101:458-63.
20. Chastre J, Fagon J. Ventilator-associated pneumonia. Am J Respir Crit Care Med 2002;165:867-903. (Pubitemid 34774654)
21. Ibrahimn EH, Ward S, Sherman G, et al. Experience with a clinical guideline for the treatment of ventilator associated pneumonia. Crit Care Med 2001;29:1109-15. (Pubitemid 32554320)
22. Shorr AF, Sherner JH, Jackson WL, Kollef MH. Invasive approaches to the diagnosis of ventilator-associated pneumonia: a meta-analysis. Crit Care Med 2005;33:46-53. (Pubitemid 40116535)
23. Van Eldere J. Multicenter surveillance of Pseudomonas aeruginosa susceptibility patterns in nosocomial infections. J Antimicrob Chemother 2003;51:347-52. (Pubitemid 36231155)
24. Gales AC, Jones RN, Forward KR, et al. Emerging importance of multidrug-resistant Acinetobacter species and Stenotrophomonas maltophilia as pathogens in seriously ill patients: geographic patterns, epidemiological features, and trends in the SENTRY Antimicrobial Surveillance Program (1997-1999). Clin Infect Dis 2001;32:S104-13.
25. Bradford PA. Extended-spectrum B-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat. Clin Microbiol Rev 2001;14:933-51.
26. Fridkin SK, Hageman J, McDougal LK, et al. Epidemiological and microbiological characterization of infections caused by Staphylococcus aureus with reduced susceptibility to vancomycin, United States, 1997-2001. Clin Infect Dis 2003;36:429-39.
27. Marquette CH, Herengt F, Mathieu D, et al. Diagnosis of pneumonia in mechanically ventilated patients: repeatability of the protected specimen brush. Am Rev Respir Dis 1993;147:211-4. (Pubitemid 23025943)
28. Gerbeaux P, Ledoray V, Boussuges A, et al. Diagnosis of nosocomial pneumonia in mechanically ventilated patients: repeatability of the bronchoalveolar lavage. Am J Respir Crit Care Med 1998;157:76-80. (Pubitemid 28071264)
29. Torres A, Santiago E. Diagnosing ventilator-associated pneumonia. N Engl J Med 2004;350:433-5. (Pubitemid 38133760)
30. Croce MA, Fabian TC, Mueller EW, et al. The appropriate diagnostic threshold for ventilator-associated pneumonia using quantitative cultures. J Trauma 2004;56:931-6. (Pubitemid 38788715)
31. Croce MA, Fabian TC, Waddle-Smith L, et al. Utility of Gram's stain and efficacy of quantitative cultures for posttraumatic pneumonia. Ann Surg 1998;227:743-55. (Pubitemid 28530924)
32. Miller PR, Meredith JW, Chang NC. Optimal threshold for diagnosis of ventilator-associated pneumonia using bronchoalveolar lavage. J Trauma 2003;55:263-8. (Pubitemid 37047394)
33. Croce MA, Fabian TC, Shaw B, et al. Analysis of charges associated with diagnosis of nosocomial pneumonia: can routine bronchoscopy be justified? J Trauma 1994;37:721-7.
34. Pham LH, Brun-Buisson C, Legrand P, et al. Diagnosis of nosocomial pneumonia in mechanically ventilated patients: comparison of a plugged telescoping catheter with the protected specimen brush. Am Rev Respir Dis 1991;143:1055-61.