메뉴 건너뛰기




Volumn 60, Issue 3, 2011, Pages 857-866

Natural killer cells from children with type 1 diabetes have defects in NKG2D-dependent function and signaling

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 15; INTERLEUKIN 2; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NATURAL KILLER CELL RECEPTOR NKG2D; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

EID: 79952369448     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db09-1706     Document Type: Article
Times cited : (51)

References (54)
  • 1
    • 0029954214 scopus 로고    scopus 로고
    • Insulin-dependent diabetes mellitus
    • DOI 10.1016/S0092-8674(00)81106-X
    • Tisch R, McDevitt H. Insulin-dependent diabetes mellitus. Cell 1996;85:291-297 (Pubitemid 26160699)
    • (1996) Cell , vol.85 , Issue.3 , pp. 291-297
    • Tisch, R.1    McDevitt, H.2
  • 2
    • 0034812119 scopus 로고    scopus 로고
    • Genetic protection from the inflammatory disease type 1 diabetes in humans and animal models
    • DOI 10.1016/S1074-7613(01)00202-3
    • Todd JA, Wicker LS. Genetic protection from the inflammatory disease type 1 diabetes in humans and animal models. Immunity 2001;15:387-395 (Pubitemid 32907386)
    • (2001) Immunity , vol.15 , Issue.3 , pp. 387-395
    • Todd, J.A.1    Wicker, L.S.2
  • 6
    • 0036082290 scopus 로고    scopus 로고
    • The role of NK cells in autoimmune disease
    • DOI 10.1080/08916930290005864
    • Baxter AG, Smyth MJ. The role of NK cells in autoimmune disease. Autoimmunity 2002;35:1-14 (Pubitemid 34678715)
    • (2002) Autoimmunity , vol.35 , Issue.1 , pp. 1-14
    • Baxter, A.G.1    Smyth, M.J.2
  • 9
    • 0020683479 scopus 로고
    • Immunologic aspects of the nonobese diabetic (NOD) mouse. Abnormalities of cellular immunity
    • Kataoka S, Satoh J, Fujiya H, et al. Immunologic aspects of the nonobese diabetic (NOD) mouse: abnormalities of cellular immunity. Diabetes 1983;32:247-253 (Pubitemid 13138268)
    • (1983) Diabetes , vol.32 , Issue.3 , pp. 247-253
    • Kataoka, S.1    Satoh, J.2    Fujiya, H.3
  • 10
    • 0035865315 scopus 로고    scopus 로고
    • Protection against diabetes and improved NK/NKT cell performance in NOD.NK1.1 mice congenic at the NK complex
    • Carnaud C, Gombert J, Donnars O, Garchon H, Herbelin A. Protection against diabetes and improved NK/NKT cell performance in NOD.NK1.1 mice congenic at the NK complex. J Immunol 2001;166:2404-2411 (Pubitemid 32173475)
    • (2001) Journal of Immunology , vol.166 , Issue.4 , pp. 2404-2411
    • Carnaud, C.1    Gombert, J.-M.2    Donnars, O.3    Garchon, H.-J.4    Herbelin, A.5
  • 12
    • 0347989293 scopus 로고    scopus 로고
    • Broadly impaired NK cell function in non-obese diabetic mice is partially restored by NK cell activation in vivo and by IL-12/IL-18 in vitro
    • DOI 10.1093/intimm/dxh002
    • Johansson SE, Hall H, Björklund J, Höglund P. Broadly impaired NK cell function in non-obese diabetic mice is partially restored by NK cell activation in vivo and by IL-12/IL-18 in vitro. Int Immunol 2004;16:1-11 (Pubitemid 38054621)
    • (2004) International Immunology , vol.16 , Issue.1 , pp. 1-11
    • Johansson, S.E.1    Hall, H.2    Bjorklund, J.3    Hoglund, P.4
  • 13
    • 0028869986 scopus 로고
    • Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice
    • Shultz LD, Schweitzer PA, Christianson SW, et al. Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice. J Immunol 1995;154:180-191
    • (1995) J Immunol , vol.154 , pp. 180-191
    • Shultz, L.D.1    Schweitzer, P.A.2    Christianson, S.W.3
  • 14
    • 0021259373 scopus 로고
    • Alterations in lymphocyte subpopulations in Type 1 (insulin-dependent) diabetes mellitus: Exploration of possible mechanisms and relationships to autoimmune phenomena
    • Herold KC, Huen A, Gould L, Traisman H, Rubenstein AH. Alterations in lymphocyte subpopulations in type 1 (insulin-dependent) diabetes mellitus: exploration of possible mechanisms and relationships to autoimmune phenomena. Diabetologia 1984;27(Suppl.):102-105 (Pubitemid 14096723)
    • (1984) Diabetologia , vol.27 , Issue.SUPPL. , pp. 102-105
    • Herold, K.C.1    Huen, A.2    Gould, L.3
  • 15
    • 0022974602 scopus 로고
    • Immunoregulatory dysfunctions in type I diabetes: Natural and antibody-dependent cellular cytotoxic activities
    • DOI 10.1007/BF00915375
    • Nair MP, Lewis EW, Schwartz SA. Immunoregulatory dysfunctions in type I diabetes: natural and antibody-dependent cellular cytotoxic activities. J Clin Immunol 1986;6:363-372 (Pubitemid 17195809)
    • (1986) Journal of Clinical Immunology , vol.6 , Issue.5 , pp. 363-372
    • Nair, M.P.N.1    Lewis, E.W.2    Schwartz, S.A.3
  • 16
    • 0022515204 scopus 로고
    • Natural killer cell and islet killer cell activities in Type 1 (insulin-dependent) diabetes
    • Negishi K, Waldeck N, Chandy G, et al. Natural killer cell and islet killer cell activities in type 1 (insulin-dependent) diabetes. Diabetologia 1986;29:352-357 (Pubitemid 16060892)
    • (1986) Diabetologia , vol.29 , Issue.6 , pp. 352-357
    • Negishi, K.1    Waldeck, N.2    Chandy, G.3
  • 17
    • 0022481060 scopus 로고
    • Natural killer cells in insulin dependent diabetes mellitus
    • Wilson RG, Anderson J, Shenton BK, White MD, Taylor RM, Proud G. Natural killer cells in insulin dependent diabetes mellitus. Br Med J (Clin Res Ed) 1986;293:244 (Pubitemid 16064229)
    • (1986) British Medical Journal , vol.293 , Issue.6541 , pp. 244
    • Wilson, R.G.1    Anderson, J.2    Shenton, B.K.3
  • 18
    • 0023543380 scopus 로고
    • Evidence that the reduced number of natural killer cells in Type 1 (insulin-dependent) diabetes may be genetically determined
    • Hussain MJ, Alviggi L, Millward BA, Leslie RD, Pyke DA, Vergani D. Evidence that the reduced number of natural killer cells in type 1 (insulin-dependent) diabetes may be genetically determined. Diabetologia 1987;30:907-911 (Pubitemid 18055846)
    • (1987) Diabetologia , vol.30 , Issue.12 , pp. 907-911
    • Hussain, M.J.1    Alviggi, L.2    Millward, B.A.3    Leslie, R.D.G.4    Pyke, D.A.5    Vergani, D.6
  • 19
    • 0025302277 scopus 로고
    • Immune responses to insulin and lymphocyte subclasses at diagnosis of insulin-dependent diabetes and one year later
    • Scheinin T, Mäenpää J, Kontiainen S. Immune responses to insulin and lymphocyte subclasses at diagnosis of insulin-dependent diabetes and one year later. Immunobiology 1990;180:431-440 (Pubitemid 20232375)
    • (1990) Immunobiology , vol.180 , Issue.4-5 , pp. 431-440
    • Scheinin, T.1    Maenpaa, J.2    Kontiainen, S.3
  • 21
  • 22
    • 11144299492 scopus 로고    scopus 로고
    • NK cell recognition
    • DOI 10.1146/annurev.immunol.23.021704.115526
    • Lanier LL. NK cell recognition. Annu Rev Immunol 2005;23:225-274 (Pubitemid 40563170)
    • (2005) Annual Review of Immunology , vol.23 , pp. 225-274
    • Lanier, L.L.1
  • 23
    • 34548247599 scopus 로고    scopus 로고
    • Promiscuity and the single receptor: NKG2D
    • DOI 10.1038/nri2144, PII NRI2144
    • Eagle RA, Trowsdale J. Promiscuity and the single receptor: NKG2D. Nat Rev Immunol 2007;7:737-744 (Pubitemid 47327391)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.9 , pp. 737-744
    • Eagle, R.A.1    Trowsdale, J.2
  • 24
    • 0142197631 scopus 로고    scopus 로고
    • Roles of the NKG2D immunoreceptor and its ligands
    • Raulet DH. Roles of the NKG2D immunoreceptor and its ligands. Nat Rev Immunol 2003;3:781-790 (Pubitemid 37328656)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.10 , pp. 781-790
    • Raulet, D.H.1
  • 26
    • 0033618624 scopus 로고    scopus 로고
    • An activating immunoreceptor complex formed by NKG2D and DAP10
    • Wu J, Song Y, Bakker AB, et al. An activating immunoreceptor complex formed by NKG2D and DAP10. Science 1999;285:730-732
    • (1999) Science , vol.285 , pp. 730-732
    • Wu, J.1    Song, Y.2    Bakker, A.B.3
  • 28
    • 38349022508 scopus 로고    scopus 로고
    • Critical role for IFN-gamma in natural killer cell-mediated protection from diabetes
    • Lee IF, Qin H, Priatel JJ, Tan R. Critical role for IFN-gamma in natural killer cell-mediated protection from diabetes. Eur J Immunol 2008;38:82-89
    • (2008) Eur J Immunol , vol.38 , pp. 82-89
    • Lee, I.F.1    Qin, H.2    Priatel, J.J.3    Tan, R.4
  • 29
    • 1642454721 scopus 로고    scopus 로고
    • Regulation of Autoimmune Diabetes by Complete Freund's Adjuvant Is Mediated by NK Cells
    • Lee IF, Qin H, Trudeau J, Dutz J, Tan R. Regulation of autoimmune diabetes by complete Freund's adjuvant is mediated by NK cells. J Immunol 2004;172:937-942 (Pubitemid 38113752)
    • (2004) Journal of Immunology , vol.172 , Issue.2 , pp. 937-942
    • Lee, I.-F.1    Qin, H.2    Trudeau, J.3    Dutz, J.4    Tan, R.5
  • 30
    • 11144256544 scopus 로고    scopus 로고
    • Protein microarrays for multiplex analysis of signal transduction pathways
    • DOI 10.1038/nm1139
    • Chan SM, Ermann J, Su L, Fathman CG, Utz PJ. Protein microarrays for multiplex analysis of signal transduction pathways. Nat Med 2004;10:1390-1396 (Pubitemid 40022723)
    • (2004) Nature Medicine , vol.10 , Issue.12 , pp. 1390-1396
    • Chan, S.M.1    Ermann, J.2    Su, L.3    Fathman, C.G.4    Utz, P.J.5
  • 32
    • 0035169507 scopus 로고    scopus 로고
    • Interleukin 15: Biology and relevance to human disease
    • DOI 10.1182/blood.V97.1.14
    • Fehniger TA, Caligiuri MA. Interleukin 15: biology and relevance to human disease. Blood 2001;97:14-32 (Pubitemid 32061238)
    • (2001) Blood , vol.97 , Issue.1 , pp. 14-32
    • Fehniger, T.A.1    Caligiuri, M.A.2
  • 33
    • 41949097030 scopus 로고    scopus 로고
    • The biology of interleukin-2
    • DOI 10.1146/annurev.immunol.26.021607.090357
    • Malek TR. The biology of interleukin-2. Annu Rev Immunol 2008;26:453-479 (Pubitemid 351600382)
    • (2008) Annual Review of Immunology , vol.26 , pp. 453-479
    • Malek, T.R.1
  • 34
    • 0035575989 scopus 로고    scopus 로고
    • TCR/self-antigen interactions drive double-negative T cell peripheral expansion and differentiation into suppressor cells
    • Priatel JJ, Utting O, Teh HS. TCR/self-antigen interactions drive double-negative T cell peripheral expansion and differentiation into suppressor cells. J Immunol 2001;167:6188-6194 (Pubitemid 33081546)
    • (2001) Journal of Immunology , vol.167 , Issue.11 , pp. 6188-6194
    • Priatel, J.J.1    Utting, O.2    Teh, H.-S.3
  • 35
    • 71649100833 scopus 로고    scopus 로고
    • Trans-presentation: A novel mechanism regulating IL-15 delivery and responses
    • Stonier SW, Schluns KS. Trans-presentation: a novel mechanism regulating IL-15 delivery and responses. Immunol Lett 2010;127:85-92
    • (2010) Immunol Lett , vol.127 , pp. 85-92
    • Stonier, S.W.1    Schluns, K.S.2
  • 36
    • 77954665674 scopus 로고    scopus 로고
    • Inhibition of NKG2D expression in NK cells by cytokines secreted in response to human cytomegalovirus infection
    • Muntasell A, Magri G, Pende D, Angulo A, López-Botet M. Inhibition of NKG2D expression in NK cells by cytokines secreted in response to human cytomegalovirus infection. Blood 2010;115:5170-5179
    • (2010) Blood , vol.115 , pp. 5170-5179
    • Muntasell, A.1    Magri, G.2    Pende, D.3    Angulo, A.4    López-Botet, M.5
  • 37
    • 0035054469 scopus 로고    scopus 로고
    • Role of NKG2D in tumor cell lysis mediated by human NK cells: Cooperation with natural cytotoxicity receptors and capability of recognizing tumors of nonepithelial origin
    • Pende D, Cantoni C, Rivera P, et al. Role of NKG2D in tumor cell lysis mediated by human NK cells: cooperation with natural cytotoxicity receptors and capability of recognizing tumors of nonepithelial origin. Eur J Immunol 2001;31:1076-1086
    • (2001) Eur J Immunol , vol.31 , pp. 1076-1086
    • Pende, D.1    Cantoni, C.2    Rivera, P.3
  • 38
    • 0036829733 scopus 로고    scopus 로고
    • Major histocompatibility complex class I-related chain A and UL16-binding protein expression on tumor cell lines of different histotypes: Analysis of tumor susceptibility to NKG2D-dependent natural killer cell cytotoxicity
    • Pende D, Rivera P, Marcenaro S, et al. Major histocompatibility complex class I-related chain A and UL16-binding protein expression on tumor cell lines of different histotypes: analysis of tumor susceptibility to NKG2D-dependent natural killer cell cytotoxicity. Cancer Res 2002;62:6178-6186 (Pubitemid 35244469)
    • (2002) Cancer Research , vol.62 , Issue.21 , pp. 6178-6186
    • Pende, D.1    Rivera, P.2    Marcenaro, S.3    Chang, C.-C.4    Biassoni, R.5    Conte, R.6    Kubin, M.7    Cosman, D.8    Ferrone, S.9    Moretta, L.10    Moretta, A.11
  • 39
    • 33744545472 scopus 로고    scopus 로고
    • NKG2D-mediated activation of cytotoxic lymphocytes: Unique signaling pathways and distinct functional outcomes
    • DOI 10.1016/j.smim.2006.03.001, PII S1044532306000376
    • Upshaw JL, Leibson PJ. NKG2D-mediated activation of cytotoxic lymphocytes: unique signaling pathways and distinct functional outcomes. Semin Immunol 2006;18:167-175 (Pubitemid 43817560)
    • (2006) Seminars in Immunology , vol.18 , Issue.3 , pp. 167-175
    • Upshaw, J.L.1    Leibson, P.J.2
  • 40
    • 33645976783 scopus 로고    scopus 로고
    • NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells
    • Upshaw JL, Arneson LN, Schoon RA, Dick CJ, Billadeau DD, Leibson PJ. NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells. Nat Immunol 2006;7:524-532
    • (2006) Nat Immunol , vol.7 , pp. 524-532
    • Upshaw, J.L.1    Arneson, L.N.2    Schoon, R.A.3    Dick, C.J.4    Billadeau, D.D.5    Leibson, P.J.6
  • 41
    • 33847053237 scopus 로고    scopus 로고
    • Altered natural killer cells in type 1 diabetic patients
    • Rodacki M, Svoren B, Butty V, et al. Altered natural killer cells in type 1 diabetic patients. Diabetes 2007;56:177-185
    • (2007) Diabetes , vol.56 , pp. 177-185
    • Rodacki, M.1    Svoren, B.2    Butty, V.3
  • 42
    • 36248957695 scopus 로고    scopus 로고
    • NKG2D signaling is coupled to the interleukin 15 receptor signaling pathway
    • DOI 10.1038/ni1524, PII NI1524
    • Horng T, Bezbradica JS, Medzhitov R. NKG2D signaling is coupled to the interleukin 15 receptor signaling pathway. Nat Immunol 2007;8:1345-1352 (Pubitemid 350138973)
    • (2007) Nature Immunology , vol.8 , Issue.12 , pp. 1345-1352
    • Horng, T.1    Bezbradica, J.S.2    Medzhitov, R.3
  • 43
    • 68649112523 scopus 로고    scopus 로고
    • Altered NK cell development and enhanced NK cell-mediated resistance to mouse cytomegalovirus in NKG2D-deficient mice
    • Zafirova B, Mandarić S, Antulov R, et al. Altered NK cell development and enhanced NK cell-mediated resistance to mouse cytomegalovirus in NKG2D-deficient mice. Immunity 2009;31:270-282
    • (2009) Immunity , vol.31 , pp. 270-282
    • Zafirova, B.1    Mandarić, S.2    Antulov, R.3
  • 45
    • 59049094662 scopus 로고    scopus 로고
    • Adaptive immune features of natural killer cells
    • Sun JC, Beilke JN, Lanier LL. Adaptive immune features of natural killer cells. Nature 2009;457:557-561
    • (2009) Nature , vol.457 , pp. 557-561
    • Sun, J.C.1    Beilke, J.N.2    Lanier, L.L.3
  • 46
    • 49249088692 scopus 로고    scopus 로고
    • Tolerance of NK cells encountering their viral ligand during development
    • Sun JC, Lanier LL. Tolerance of NK cells encountering their viral ligand during development. J Exp Med 2008;205:1819-1828
    • (2008) J Exp Med , vol.205 , pp. 1819-1828
    • Sun, J.C.1    Lanier, L.L.2
  • 47
    • 49249086644 scopus 로고    scopus 로고
    • Continuous engagement of a self-specific activation receptor induces NK cell tolerance
    • Tripathy SK, Keyel PA, Yang L, et al. Continuous engagement of a self-specific activation receptor induces NK cell tolerance. J Exp Med 2008;205:1829-1841
    • (2008) J Exp Med , vol.205 , pp. 1829-1841
    • Tripathy, S.K.1    Keyel, P.A.2    Yang, L.3
  • 48
    • 24944500112 scopus 로고    scopus 로고
    • Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillance
    • DOI 10.1038/ni1239, PII N1239
    • Oppenheim DE, Roberts SJ, Clarke SL, et al. Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillance. Nat Immunol 2005;6:928-937 (Pubitemid 43090448)
    • (2005) Nature Immunology , vol.6 , Issue.9 , pp. 928-937
    • Oppenheim, D.E.1    Roberts, S.J.2    Clarke, S.L.3    Filler, R.4    Lewis, J.M.5    Tigelaar, R.E.6    Girardi, M.7    Hayday, A.C.8
  • 49
    • 0037017377 scopus 로고    scopus 로고
    • Dendritic and natural killer cells cooperate in the control/switch of innate immunity
    • Zitvogel L. Dendritic and natural killer cells cooperate in the control/switch of innate immunity. J Exp Med 2002;195:F9-F14 (Pubitemid 34461485)
    • (2002) Journal of Experimental Medicine , vol.195 , Issue.3
    • Zitvogel, L.1
  • 50
    • 4344610099 scopus 로고    scopus 로고
    • The regulatory role of natural killer cells in multiple sclerosis
    • DOI 10.1093/brain/awh219
    • Takahashi K, Aranami T, Endoh M, Miyake S, Yamamura T. The regulatory role of natural killer cells in multiple sclerosis. Brain 2004;127:1917-1927 (Pubitemid 39150251)
    • (2004) Brain , vol.127 , Issue.9 , pp. 1917-1927
    • Takahashi, K.1    Aranami, T.2    Endoh, M.3    Miyake, S.4    Yamamura, T.5
  • 51
    • 0030712367 scopus 로고    scopus 로고
    • Regulation of experimental autoimmune encephalomyelitis by natural killer (NK) cells
    • DOI 10.1084/jem.186.10.1677
    • Zhang B, Yamamura T, Kondo T, Fujiwara M, Tabira T. Regulation of experimental autoimmune encephalomyelitis by natural killer (NK) cells. J Exp Med 1997;186:1677-1687 (Pubitemid 27506281)
    • (1997) Journal of Experimental Medicine , vol.186 , Issue.10 , pp. 1677-1687
    • Zhang, B.-N.1    Yamamura, T.2    Kondo, T.3    Fujiwara, M.4    Tabira, T.5
  • 52
    • 0027484294 scopus 로고
    • Lymphocyte subsets in a large cohort of patients with systemic lupus erythematosus
    • Erkeller-Yüsel F, Hulstaart F, Hannet I, Isenberg D, Lydyard P. Lymphocyte subsets in a large cohort of patients with systemic lupus erythematosus. Lupus 1993;2:227-231 (Pubitemid 23295636)
    • (1993) Lupus , vol.2 , Issue.4 , pp. 227-231
    • Erkeller-Yuksel, F.1    Hulstaart, F.2    Hannet, I.3    Isenberg, D.4    Lydyard, P.5
  • 53
    • 0027514685 scopus 로고
    • The development of autoimmunity in C57BL/6 lpr mice correlates with the disappearance of natural killer type 1-positive cells: Evidence for their suppressive action on bone marrow stem cell proliferation, B cell immunoglobulin secretion, and autoimmune symptoms
    • DOI 10.1084/jem.177.1.155
    • Takeda K, Dennert G. The development of autoimmunity in C57BL/6 lpr mice correlates with the disappearance of natural killer type 1-positive cells: evidence for their suppressive action on bone marrow stem cell proliferation, B cell immunoglobulin secretion, and autoimmune symptoms. J Exp Med 1993;177:155-164 (Pubitemid 23008095)
    • (1993) Journal of Experimental Medicine , vol.177 , Issue.1 , pp. 155-164
    • Takeda, K.1    Dennert, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.