Effects of silencing transforming growth factor-β1 by RNA interference plasmid on rat renal allograft fibrosis using smads pathway

Urology

Volumn 77, Issue 3, 2011, Pages 762.e1-762.e7

  Yin, Zhikang ^a   Xia, Yuguo ^b   Luo, Chunli ^a   Zhang, Jiamo ^a   He, Yunfeng ^a   Wu, Xiaohou ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b CHENGDU UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; CREATININE; MESSENGER RNA; SHORT HAIRPIN RNA; SMAD3 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UREA; UVOMORULIN;

ANIMAL TISSUE; ARTICLE; CELL TRANSDIFFERENTIATION; CONTROLLED STUDY; CREATININE BLOOD LEVEL; FIBROBLAST; GENE SILENCING; GENE TARGETING; GENETIC TRANSFECTION; KIDNEY ALLOGRAFT; KIDNEY FIBROSIS; KIDNEY TUBULE CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; UPREGULATION; UREA NITROGEN BLOOD LEVEL;

EID: 79952364184     PISSN: 00904295     EISSN: 15279995     Source Type: Journal    
DOI: 10.1016/j.urology.2010.09.052     Document Type: Article

References (22)

1. K. Yoshida, T. Endo, and T. Saito Cadaveric renal transplantation from non-heart-beating donors with graft survival for more than 10 years Transplant Proc 34 2002 2604 2607 (Pubitemid 35304850)
2. T.A. Wynn Cellular and molecular mechanisms of fibrosis J Pathol 214 2008 199 210 (Pubitemid 351160157)
3. J.M. Campistol, P. Iigo, and S. Larios Role of transplantation: transforming growth factor-β1 in the progression of chronic allograft nephropathy Nephrol Dial Transplant 16 suppl 2001 114 116 (Pubitemid 32492521)
4. H. Hamajima, I. Ozaki, and H. Zhang Modulation of the transforming growth factor-beta1-induced Smad phosphorylation by the extracellular matrix receptor beta1-integrin Int J Oncol 35 2009 1441 1447
5. R.K. Bhogal, C.M. Stoica, and T.L. McGaha Molecular aspects of regulation of collagen Gene expression in fibrosis J Clin Immunol 25 2005 592 603 (Pubitemid 43011750)
6. M. Zeisberg, and R. Kalluri The role of epithelial-to-mesenchymal transition in renal fibrosis J Mol Med 82 2004 175 181 (Pubitemid 38392167)
7. J.H. Li, H.J. Zhu, and X.R. Huang Smad7 inhibits fibrotic effect of TGF-beta on renal tubular epithelial cells by blocking Smad2 activation J Am Soc Nephrol 13 2002 1464 1472 (Pubitemid 34579235)
8. H. Maruyama, N. Higuchi, and S. Kameda Sustained transgene expression in rat kidney with naked plasmid DNA and PCR-amplified DNA fragments J Biochem 137 2005 373 380 (Pubitemid 40628444)
9. N. Liu, X.L. Zhang, and C.D. Liang Dynamic changes of alpha-AR beta1-AR and beta2-AR expression during hepatic fibrogenesis Zhonghua Gan Zang Bing Za Zhi 17 2009 653 656
10. Y.P. Xin, G.Y. Yuan, and Y.P. Lu Explorative study on mechanism and drug intervention for chronic allograft nephropathy induced by renal ischemia-reperfusion injury Sichuan Xue Xue Bao Yi Xue Ban 38 2007 918 923
11. H. Wahhabaghai, B. Rasoulian, and M. Esmaili Hyperoxia-induced protection against rat's renal ischemic damage: relation to oxygen exposure time Ren Fail 31 2009 514 521
12. H. Maruyama, N. Higuchi, and S. Kameda Rat kidney-targeted naked plasmid DNA transfer by retrograde injection into the renal vein Mol Biotechnol 27 2004 23 31 (Pubitemid 41490604)
13. S. Van Linthout, U. Seeland, and A. Riad Reduced MMP-2 activity contributes to cardiac fibrosis in experimental diabetic cardiomyopathy Basic Res Cardiol 103 2008 319 327
14. J.S. Kang, C. Liu, and R. Derynck New regulatory mechanisms of TGF-beta receptor function Trends Cell Biol 19 2009 385 394
15. D.D. Luo, A. Phillips, and D. Fraser Bone morphogenetic protein-7 inhibits proximal tubular epithelial cell Smad3 signaling via increased SnoN expression Am J Pathol 176 2010 1139 1147
16. R. Kalluri, and E.G. Neilson Epithelial-mesenchymal transition and its implications for fibrosis J Clin Invest 112 2003 1776 1784 (Pubitemid 38063698)
17. M. Pang, J. Kothapally, and H. Mao Inhibition of histone deacetylase activity attenuates renal fibroblast activation and interstitial fibrosis in obstructive nephropathy Am J Physiol Ren Physiol 297 2009 996 1005
18. M.P. Rastaldi Epithelial-mesenchymal transition and its implications for the development of renal tubulointerstitial fibrosis J Nephrol 19 2006 407 412 (Pubitemid 44823195)
19. M. Iwano, D. Plieth, and T.M. Danoff Evidence that fibroblasts derive from epithelium during tissue fibrosis J Clin Invest 110 2002 341 350 (Pubitemid 34847966)
20. A. Dixon, and C. Maric 17β-Estradiol attenuates diabetic kidney disease by regulating extracellular matrix and transforming growth factor-β protein expression and signaling Am J Physiol Ren Physiol 293 2007 1678 1690
21. C.E. Hills, and P.E. Squires TGF-beta1-induced epithelial-to-mesenchymal transition and therapeutic intervention in diabetic nephropathy Am J Nephrol 31 2009 68 74
22. N. Honda, T. Miyai, and R. Nejima Effect of latanoprost on the expression of matrix metalloproteinases and tissue inhibitor of metalloproteinase 1 on the ocular surface Arch Ophthalmol 128 2010 466 471