A novel alkaloid, aristopyridinone A and anti-inflammatory phenanthrenes isolated from Aristolochia manshuriensis

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 6, 2011, Pages 1792-1794

  Chung, Yu Ming ^a   Chang, Fang Rong ^a,d,e   Tseng, Tseng Fu ^a   Hwang, Tsong Long ^b   Chen, Lei Chin ^c   Wu, Shou Fang ^a   Lee, Chia Lin ^a,g   Lin, Zu Yau ^d   Chuang, Li Yeh ^c   Su, Jinu Huang ^a   Wu, Yang Chang ^a,f,g  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c I SHOU UNIVERSITY   (Taiwan)

^d KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^e NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^f CHINA MEDICAL UNIVERSITY   (Taiwan)

^g CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Anti inflammatory; Aristolamide II; Aristolochia manshuriensis; Aristopyridinone A; Elastase release; Human neutrophils; Phenanthrene; Superoxide anion

Indexed keywords

6 METHOXYARISTOLIC ACID METHYL ESTER; ALKALOID DERIVATIVE; ANTIINFLAMMATORY AGENT; ARISTOLAMIDE; ARISTOLAMIDE II; ARISTOLATAMS IIIA; ARISTOLIC ACID METHYL ESTER; ARISTOLOCHIA MANSHURIENSIS EXTRACT; ARISTOLOCHIC ACID; ARISTOLOCHIC ACID I; ARISTOLOCHIC ACID I METHYL ESTER; ARISTOLOCHIC ACID IIIA; ARISTOLOCHIC ACID IVA; ARISTOPYRIDINONE A; ELASTASE; GENISTEIN; PHENANTHRENE DERIVATIVE; PLANT EXTRACT; SUPEROXIDE; UNCLASSIFIED DRUG;

ARISTOLOCHIA MANSHURIENSIS; ARTICLE; CONCENTRATION RESPONSE; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; ENZYME RELEASE; HUMAN; IC 50; NEUTROPHIL; NONHUMAN;

ANTI-INFLAMMATORY AGENTS; ARISTOLOCHIA; BIPHENYL COMPOUNDS; CELL LINE, TUMOR; ETHERS; HUMANS; INHIBITORY CONCENTRATION 50; LEUKOCYTE ELASTASE; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHILS; QUINOLINES;

ARISTOLOCHIA MANSHURIENSIS;

EID: 79952360536     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.01.067     Document Type: Article

References (17)

1. N.Y. Chiu, and K.H. Chang The Illustrated Medicinal Plant of Taiwan 1 1987 Southern Materials Center, Inc. Taipei 22
2. L. Yang, X. Li, and H. Wang Nephrol. Dial. Transplant. 22 2007 445
3. A. Tada, K. Sase, I. Ohmura, J. Shoji, and O. Tanaka Syoyakugaku Zasshi 23 1969 99
4. V.G. Rucker, and B.S. Chung Planta Med. 27 1975 68
5. U. Mengs, and C.D. Stotzem Arch. Toxicol. 67 1993 68
6. M. Vanhaelen, R. Vanhaelen-Fastre, P. But, and J.L. Vanherweghem Lancet 343 1994 174
7. H.H. Schmeiser, C.A. Bieler, M. Wiessler, Van. Ypersele, C. de Strihou, and J.P. Cosyms Cancer Res. 56 1996 2025
8. 3Na, 246.1130).
9. 3, 266.0818).
10. S.C. Pakrashi, P. Ghoshdastidar, S. Basu, and B. Achari Phytochemistry 16 1977 1103
11. P.L. Wu, G.C. Su, and T.S. Wu J. Nat. Prod. 66 2003 996
12. D.B. Mix, H. Guinaudeau, and M. Shamma J. Nat. Prod. 45 1982 657
13. S. Mukhopadhyay, S. Funayama, G.A. Cordell, and H.H.S. Fong J. Nat. Prod. 46 1983 507
14. T.S. Wu, L.F. Ou, and C.M. Teng Phytochemistry 34 1994 1063
15. J.L. Nortier, and J.L. Vanherweghem Toxicology 181 2002 577
16. J.L. Vanherweghem, M. Depierreux, C. Tielemans, D. Abramowicz, M. Dratwa, M. Jadoul, C. Richard, D. Vandervelde, D. Verbeelen, R.V. Faster, and M. Vanhaelen Lancet 341 1993 388
17. T.L. Hwang, Y.C. Su, H.L. Chang, Y.L. Leu, P.J. Chung, L.M. Kuo, and Y.J. Chang J. Lipid Res. 50 2009 1395