Ca2+-dependent phosphorylation of RyR2 can uncouple channel gating from direct cytosolic Ca2+ regulation

Journal of Membrane Biology

Volumn 240, Issue 1, 2011, Pages 21-33

  Carter, Simon ^a   Pitt, Samantha J ^a   Colyer, John ^b   Sitsapesan, Rebecca ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Ca2+ release channel; Cardiac; Excitation contraction coupling; Ion channel; Ryanodine receptor; Sarcoplasmic reticulum

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM; CYCLIC AMP DEPENDENT PROTEIN KINASE; MAGNESIUM; PHOSPHATASE; PHOSPHOTRANSFERASE; RYANODINE RECEPTOR 2;

ANIMAL TISSUE; ARTICLE; BILAYER MEMBRANE; CHANNEL GATING; NONHUMAN; PROTEIN PHOSPHORYLATION; RECEPTOR SENSITIVITY; REGULATORY MECHANISM; SARCOPLASMIC RETICULUM; SHEEP;

ANIMALS; CALCIUM; CALCIUM CHANNELS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYTOSOL; HEART FAILURE; HOMEOSTASIS; HUMANS; ION CHANNEL GATING; LIPID BILAYERS; MYOCARDIUM; MYOCYTES, CARDIAC; PHOSPHOPROTEIN PHOSPHATASES; PHOSPHORYLATION; RYANODINE; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM; SERINE; SHEEP;

EID: 79952360394     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00232-011-9339-9     Document Type: Article

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