Expression of tropomyosin-κ induces dilated cardiomyopathy and depresses cardiac myofilament tension by mechanisms involving cross-bridge dependent activation and altered tropomyosin phosphorylation

Journal of Muscle Research and Cell Motility

Volumn 31, Issue 5-6, 2011, Pages 315-322

  Karam, Chehade N ^a   Warren, Chad M ^a   Rajan, Sudarsan ^b   De Tombe, Pieter P ^c   Wieczorek, David F ^b   Solaro, R John ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

ATPase; Calcium sensitivity; Sarcomeric proteins; Tension cost; Thin filament regulation

Indexed keywords

CALCIUM; TROPOMYOSIN;

ANIMAL; ARTICLE; CONGESTIVE CARDIOMYOPATHY; GENETICS; HEART CONTRACTION; METABOLISM; MICROFILAMENT; MOUSE; PATHOPHYSIOLOGY; PHOSPHORYLATION; TRANSGENIC MOUSE;

ANIMALS; CALCIUM; CARDIOMYOPATHY, DILATED; MICE; MICE, TRANSGENIC; MICROFILAMENTS; MYOCARDIAL CONTRACTION; PHOSPHORYLATION; TROPOMYOSIN;

MUS MUSCULUS;

EID: 79952317898     PISSN: 01424319     EISSN: 15732657     Source Type: Journal    
DOI: 10.1007/s10974-010-9237-2     Document Type: Article

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