Colon-specific contractile responses to tetrodotoxin in the isolated mouse gastrointestinal tract

Autonomic and Autacoid Pharmacology

Volumn 31, Issue 1-2, 2011, Pages 21-30

  Okuno, Y ^a   Kondo, T ^a   Saeki, A ^a   Uchida, E ^a   Teraoka, H ^a   Kitazawa, T ^a  

^a RAKUNO GAKUEN UNIVERSITY   (Japan)

Author keywords

Contraction; Inhibitory nerves; Mouse colon; Nitric oxide; Tetrodotoxin

Indexed keywords

1,1 DIMETHYL 4 PHENYLPIPERAZINIUM; APAMIN; ARGININE; H [1,2,4]OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; LIDOCAINE; N [(2,6 DIMETHYLPHENYL)CARBAMOYLMETHYL]TRIMETHYLAMMONIUM; N(G) NITROARGININE METHYL ESTER; NITROPRUSSIDE SODIUM; SODIUM CHANNEL BLOCKING AGENT; TETRODOTOXIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COLON; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; GASTROINTESTINAL TRACT; MALE; MOUSE; MUSCLE CONTRACTION; MUSCLE TONE; NONHUMAN; SENSITIVITY ANALYSIS; SMALL INTESTINE; STOMACH;

ANIMALS; APAMIN; ARGININE; COLON; DIMETHYLPHENYLPIPERAZINIUM IODIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GASTROINTESTINAL TRACT; MALE; MICE; MICE, INBRED STRAINS; MUSCLE CONTRACTION; MUSCLE RELAXATION; MUSCLE, SMOOTH; NG-NITROARGININE METHYL ESTER; NITROPRUSSIDE; OXADIAZOLES; QUINOXALINES; SODIUM CHANNEL BLOCKERS; TETRODOTOXIN;

EID: 79952300348     PISSN: 14748665     EISSN: 14748673     Source Type: Journal    
DOI: 10.1111/j.1474-8673.2011.00462.x     Document Type: Article

References (31)

1. AULI, M., MARTINEZ, E., GALLEGO, D., OPAZO, A., ESPIN, F., MARTI-GALLOSTRA, M. & JIMENEZ CLAVE, P. (2008). Effects of excitatory and inhibitory neurotransmission on motor patterns of human sigmoid colon in vitro. Br. J. Pharmacol., 155, 1043-1055.
2. BOECKXSTAENS, G.E., PELCKMANS, P.A., HERMAN, A.G. & VAN MAERCKE, Y.M. (1993). Involvement of nitric oxide in the inhibitory innervation of the human isolated colon. Gastroenterology, 104, 690-697.
3. BOLTON, T.B. (1979). Mechanisms of action of transmitters and other substances on smooth muscle. Physiol. Rev., 59, 606-718.
4. BOLTON, T.B., PRESTWICH, S.A., ZHOLOS, A.U. & GORDIENKO, D.V. (1999). Excitation-contraction coupling in gastrointestinal and other smooth muscles. Annu. Rev. Physiol., 61, 85-115.
5. BORJESSON, L., NORDGREN, S. & DELBRO, D.S. (1997). DMPP causes relaxation of rat distal colon by a purinergic and a nitrergic mechanisms. Eur. J. Pharmacol., 334, 223-231.
6. BORTOFF, A. & MULLER, R. (1975). Stimulation of intestinal smooth muscle by atropine, procaine and tetrodotoxin. Am. J. Physiol., 229, 1609-1613.
7. BURNSTOCK, G. (2007). Physiology and pathophysiology of purinergic neurotransmission. Physiol. Rev., 87, 659-797.
8. CABALLERO-ALOMAR, C., SANTOS, C., LOPEZ, D., MITJAVILA, M.T. & PUIG-PARELLADA, P. (2003). Sources and implications of basal nitric oxide in spontaneous contractions of guinea pig tenia caeci. Am. J. Physiol., 285, G747-G753.
9. CUEVAS, J. & ADAMS, D.J. (1994). Local anaesthetic blockade of neuronal nicotinic ACh receptor channels in rat parasympathetic ganglion cells. Br. J. Pharmacol., 111, 663-672.
10. DE MAN, J.G., DE WINTER, B.Y., HERMAN, A.G. & PELCKMANS, P.A. (2007). Study on the cyclic GMP-dependency of relaxations to endogenous and exogenous nitric oxide in the mouse gastrointestinal tract. Br. J. Pharmacol., 150, 88-96.
11. GERSHON, M.D. (1967). Effects of tetrodotoxin on innervated smooth muscle preparations. Br. J. Pharmacol. Chemother., 29, 259-279.
12. GOLD, M.S. & THUT, P.D. (2001). Lithium increases potency of lidocaine-induced block of voltage-gated Na currents in rat sensory neurons in vitro. J. Pharmacol. Exp. Ther., 299, 705-711.
13. HOLZER, P. & HOLZER-PETSCHE, U. (1997). Tachykinins in the gut. Part I. Expression, release and motor function. Pharmarcol. Ther., 73, 173-217.
14. KITAZAWA, T. (1984). Evidences that endogenous 5-hydroxytryptamine participates in the contractile response to morphine in the rat isolated colon. Kitasato Arch. Exp. Med., 57, 47-56.
15. LEFEBVRE, R.A., SMITS, G.J. & TIMMERMANS, J.P. (1995). Study of NO and VIP as non-adrenergic non-cholinergic neurotransmitters in the pig gastric fundus. Br. J. Pharmacol., 116, 2017-2026.
16. MENZIES, J.R.W. & CORBETT, A.D. (2000). Nociceptin inhibits tonic nitric oxide release in the mouse isolated proximal colon. Eur. J. Pharmacol., 388, 183-186.
17. MIDDLETON, S.J., CUTHBERT, A.W., SHORTHOUSE, M. & HUNTER, J.O. (1993). Nitric oxide affects mammalian distal colonic smooth muscle by tonic neural inhibition. Br. J. Pharmacol., 108, 974-979.
18. + channels. Br. J. Pharmacol., 127, 514-520.
19. NARAHASHI, T. (1972). Mechanism of action of tetrodotoxin and saxitoxin on excitable membranes. Fed. Proc., 31, 1124-1132.
20. POWELL, A.K. & BYWATER, R.A. (2001). Endogenous nitric oxide release modulates the direction and frequency of colonic migrating motor complexes in the isolated mouse colon. Neurogastroenterol. Motil., 13, 221-228.
21. REISER, G., LOFFLER, F. & HAMPRECHT, B. (1983). Tetrodotoxin-sensitive ion channels characterized in glial and neuronal cells from rat brain. Brain Res., 261, 335-340.
22. SANDERS, K.M. & WARD, S.M. (1992). Nitric oxide as a mediator of nonadrenergic noncholinergic neurotransmission. Am. J. Physiol., 262, G379-G392.
23. SANDERS, K.M., KOH, S.D. & WARD, S.M. (2006). Interstitial cells of Cajal as pacemakers in the gastrointestinal tract. Annu. Rev. Physiol., 68, 307-343.
24. SERIO, R., ALESSANDRO, M., GRAZIA ZIZZO, M., TAMBURELLO, M. & MULE, F. (2003). Neurotransmitters involved in the fast inhibitory junctional potentials in mouse distal colon. Eur. J. Pharmacol., 460, 183-190.
25. SPENCER, N.J., BYWATER, R.A.R., HILMAN, M.E. & TAYLOR, G.S. (1998). Spontaneous and evoked inhibitory junctional potentials in the circular muscle layer of mouse colon. J. Auton. Nerv. Syst., 69, 115-121.
26. SUTHAMNATPONG, N., HATA, F., KANADA, A., TAKEUCHI, T. & YAGASAKI, O. (1993). Mediators of nonadrenergic, noncholinergic inhibition in the proximal, middle and distal regions of rat colon. Br. J. Pharmacol., 108, 348-355.
27. TAKAHASHI, T. & OWYANG, C. (1998). Regional differences in the nitrergic innervation between the proximal and distal colon in rats. Gastroenterology, 115, 1504-1512.
28. TONINI, M., LECCHINI, S., FRIGO, G. & CREMA, A. (1974). Action of tetrodotoxin on spontaneous electrical activity of smooth muscle preparations. Eur. J. Pharmacol., 29, 236-240.
29. VAN ASSCHE, G., DEPOORTERE, I., THIJS, T., JANNSEN, J.J. & PEETERS, T. (1997). Concentration-dependent stimulation of cholinergic motor nerves or smooth muscle by [Nle13]motilin in the isolated rabbit gastric antrum. Eur. J. Pharmacol., 337, 267-274.
30. WOOD, J.D. (1972). Excitation of intestinal muscle by atropine, tetrodotoxin, and xylocaine. Am. J. Physiol., 222, 118-125.
31. YU, Y., CUI, Y., WANG, X., LAI, L., WANG, C., FAN, Y., LIU, J. & WANG, R. (2007). In vitro characterization of the effects of endomorphin 1 and 2, endogenous ligands for μ-opiod receptors, on mouse colonic motility. Biochem. Pharmacol., 73, 1384-1393.