Tonic inhibitory action by nitric oxide on spontaneous mechanical activity in rat proximal colon: Involvement of cyclic GMP and apamin-sensitive K+ channels

British Journal of Pharmacology

Volumn 127, Issue 2, 1999, Pages 514-520

  Mule F ^a,b   D'Angelo, S ^a   Serio, R ^a  

^a UNIVERSITY OF PALERMO   (Italy)

^b UNIVERSITY OF CALABRIA   (Italy)

Author keywords

Apamin sensitive K+ channels; Colon; Cyclic GMP; Gastrointestinal motility; Neural tonic inhibition; Nitric oxide; ODQ

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; APAMIN; CYCLIC GMP; CYCLIC GMP PHOSPHODIESTERASE; GUANYLATE CYCLASE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITROPRUSSIDE SODIUM; POTASSIUM CHANNEL; ZAPRINAST;

ANIMAL TISSUE; ARTICLE; ASCENDING COLON; COLON MOTILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; INTESTINE CONTRACTION; INTESTINE PRESSURE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

3',5'-CYCLIC-GMP PHOSPHODIESTERASE; 8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ANIMALS; COLON; CYCLIC GMP; ENZYME INHIBITORS; GUANYLATE CYCLASE; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE DONORS; NITRIC OXIDE SYNTHASE; NITROPRUSSIDE; OXADIAZOLES; PHOSPHODIESTERASE INHIBITORS; POTASSIUM CHANNELS; PURINONES; QUINOXALINES; RATS; RATS, WISTAR;

EID: 0033062524     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702537     Document Type: Article

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