Acidosis induces relaxation mediated by nitric oxide and potassium channels in rat thoracic aorta

European Journal of Pharmacology

Volumn 656, Issue 1-3, 2011, Pages 88-93

  Celotto, Andréa C ^a   Restini, Carolina B A ^a   Capellini, Verena K ^a   Bendhack, Lusiane M ^a   Evora, Paulo R B ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Acidosis; Aorta; Nitric oxide; Potassium channel

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; APAMIN; GLIBENCLAMIDE; INDOMETACIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PHENYLEPHRINE; POTASSIUM CHLORIDE; SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL;

ACIDIFICATION; ACIDOSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL REACTIVITY; BLOOD VESSEL TONE; CELL ISOLATION; CONTROLLED STUDY; ENDOTHELIUM CELL; FLOW CYTOMETRY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; THORACIC AORTA; VASODILATATION;

ACIDOSIS; ANIMALS; AORTA, THORACIC; EXTRACELLULAR SPACE; FLOW CYTOMETRY; MALE; NITRIC OXIDE; POTASSIUM CHANNELS; RATS; RATS, WISTAR; VASODILATION;

EID: 79952281018     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.01.053     Document Type: Article

References (42)

1. C. Aalkjaer, and L. Poston Effects of pH on vascular tension: which are the important mechanisms? J. Vasc. Res. 33 1996 347 359 (Pubitemid 26316359)
2. A.S. Adeagbo, and C.R. Triggle Varying extracellular [K+]: a functional approach to separating EDHF- and EDNO-related mechanisms in perfused rat mesenteric arterial bed J. Cardiovasc. Pharmacol. 21 1993 423 429 (Pubitemid 23062956)
3. H.J. Adrogue, and N.E. Madias Management of life-threatening acid-base disorders. First of two parts N. Engl. J. Med. 338 1998 26 34 (Pubitemid 28040173)
4. C. Austin, and S. Wray Extracellular pH signals affect rat vascular tone by rapid transduction into intracellular pH changes J. Physiol. 466 1993 1 8 (Pubitemid 23225214)
5. N. Balasubramanyan, T.R. Halla, N.S. Ghanayem, and J.B. Gordon Endothelium-independent and -dependent vasodilation in alkalotic and acidotic piglet lungs Pediatr. Pulmonol. 30 2000 241 248
6. Bolotina, V.M., Najibi, S., Palacino, J.J., Pagano, P.J.,Cohen, R.A., 1994. Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle. Nature. 368, 850-53. (Pubitemid 24137748)
7. A.C. Celotto, V.K. Capellini, C.F. Baldo, M.B. Dalio, A.J. Rodrigues, and P.R. Evora Effects of acid-base imbalance on vascular reactivity Braz. J. Med. Biol. Res. 41 2008 439 445
8. A.C. Celotto, S.Y. Fukada, F.R. Laurindo, R. Haddad, M.N. Eberlin, and A.M. de Oliveira Chronic hyperhomocysteinemia impairs vascular function in ovariectomized rat carotid arteries Amino Acids 38 2010 1515 1522
9. H.A. de Morais, J.F. Bach, and S.P. DiBartola Metabolic acid-base disorders in the critical care unit Vet. Clin. North Am. Small Anim. Pract. 38 2008 559 574 x-xi (Pubitemid 351472545)
10. K. Furukawa, J. Komaba, H. Sakai, and Y. Ohizumi The mechanism of acidic pH-induced contraction in aortae from SHR and WKY rats enhanced by increasing blood pressure Br. J. Pharmacol. 118 1996 485 492 (Pubitemid 26180961)
11. Y. Gao, A.K. Tassiopoulos, D.J. McGraw, M.C. Hauser, E.M. Camporesi, and T.S. Hakim Segmental pulmonary vascular responses to changes in pH in rat lungs: role of nitric oxide Acta Anaesthesiol. Scand. 43 1999 64 70 (Pubitemid 29014114)
12. W.H. Gaskell On the tonicity of the heart and blood vessels J. Physiol. 3 1880 48 92
13. J. Gurevicius, M.R. Salem, A.A. Metwally, J.M. Silver, and G.J. Crystal Contribution of nitric oxide to coronary vasodilation during hypercapnic acidosis Am. J. Physiol. 268 1995 H39 H47
14. K. Hattori, S. Tsuchida, H. Tsukahara, M. Mayumi, T. Tanaka, L. Zhang, T. Taniguchi, and I. Muramatsu Augmentation of NO-mediated vasodilation in metabolic acidosis Life Sci. 71 2002 1439 1447 (Pubitemid 34786287)
15. T. Horiuchi, H.H. Dietrich, K. Hongo, T. Goto, and R.G. Dacey Jr. Role of endothelial nitric oxide and smooth muscle potassium channels in cerebral arteriolar dilation in response to acidosis Stroke 33 2002 844 849 (Pubitemid 34204015)
16. J.M. Hyvelin, C. O'Connor, and P. McLoughlin Effect of changes in pH on wall tension in isolated rat pulmonary artery: role of the RhoA/Rho-kinase pathway Am. J. Physiol. Lung Cell. Mol. Physiol. 287 2004 L673 L684
17. V.N. Iarysev, and O.V. Karachentseva The contractile activity of the isolated mesenteric artery at different pH values of the perfusion solution Fiziol. Zh. Im. I. M. Sechenova 82 1996 28 36
18. L.J. Ignarro Endothelium-derived nitric oxide: actions and properties FASEB J. 3 1989 31 36 (Pubitemid 19042562)
19. H. Ishizaka, and L. Kuo Acidosis-induced coronary arteriolar dilation is mediated by ATP-sensitive potassium channels in vascular smooth muscle Circ. Res. 78 1996 50 57 (Pubitemid 26004120)
20. H. Ishizaka, S.R. Gudi, J.A. Frangos, and L. Kuo Coronary arteriolar dilation to acidosis: role of ATP-sensitive potassium channels and pertussis toxin-sensitive G proteins Circulation 99 1999 558 563 (Pubitemid 29061873)
21. J.A. Kellum Determinants of blood pH in health and disease Crit. Care 4 2000 6 14 (Pubitemid 30126386)
22. H. Kinoshita, and Z.S. Katusic Role of potassium channels in relaxations of isolated canine basilar arteries to acidosis Stroke 28 1997 433 437 discussion 437-438
23. K. Kitamura, and M. Kamouchi K channel openers activate different K channels in vascular smooth muscle cells Cardiovasc. Drugs Ther. 7 Suppl 3 1993 539 546 (Pubitemid 23306556)
24. H.A. Kontos, and E.P. Wei Arginine analogues inhibit responses mediated by ATP-sensitive K + channels Am. J. Physiol. 271 1996 H1498 H1506
25. C.Y. Kwan, W.B. Zhang, T.K. Kwan, and Y. Sakai In vitro relaxation of vascular smooth muscle by atropine: involvement of K + channels and endothelium Naunyn Schmiedebergs Arch. Pharmacol. 368 2003 1 9 (Pubitemid 36960478)
26. Li, P.L., Zou, A.P., Campbell, W.B., 1997. Regulation of potassium channels in coronary arterial smooth muscle by endothelium-derived vasodilators. Hypertension. 29, 262-67. (Pubitemid 27074053)
27. U. Lindauer, J. Vogt, S. Schuh-Hofer, J.P. Dreier, and U. Dirnagl Cerebrovascular vasodilation to extraluminal acidosis occurs via combined activation of ATP-sensitive and Ca2+-activated potassium channels J. Cereb. Blood Flow Metab. 23 2003 1227 1238 (Pubitemid 37229526)
28. D. Lopez, A. Rodriguez-Sinovas, L. Agullo, J. Inserte, A. Cabestrero, and D. Garcia-Dorado Acidic reoxygenation protects against endothelial dysfunction in rat aortic rings submitted to simulated ischemia Am. J. Physiol. Heart Circ. Physiol. 295 2008 H2409 H2416
29. R. Loutzenhiser, Y. Matsumoto, W. Okawa, and M. Epstein H(+)-induced vasodilation of rat aorta is mediated by alterations in intracellular calcium sequestration Circ. Res. 67 1990 426 439 (Pubitemid 20242584)
30. J.G. Matthews, J.E. Graves, and L. Poston Relationships between pHi and tension in isolated rat mesenteric resistance arteries J. Vasc. Res. 29 1992 330 340
31. + channels. Circulation. 99, 3132-38. (Pubitemid 29289078)
32. A. Modin, H. Bjorne, M. Herulf, K. Alving, E. Weitzberg, and J.O. Lundberg Nitrite-derived nitric oxide: a possible mediator of 'acidic-metabolic' vasodilation Acta Physiol. Scand. 171 2001 9 16 (Pubitemid 32324395)
33. M. Mukohda, H. Yamawaki, H. Nomura, M. Okada, and Y. Hara Methylglyoxal inhibits smooth muscle contraction in isolated blood vessels J. Pharmacol. Sci. 109 2009 305 310
34. J.W. Phillis, D. Song, and M.H. O'Regan Mechanisms involved in coronary artery dilatation during respiratory acidosis in the isolated perfused rat heart Basic Res. Cardiol. 95 2000 93 97 (Pubitemid 30251264)
35. D.K. Rohra, S.Y. Saito, and Y. Ohizumi Functional role of Cl- channels in acidic pH-induced contraction of the aorta of spontaneously hypertensive and Wistar Kyoto rats Eur. J. Pharmacol. 453 2002 279 286 (Pubitemid 35223521)
36. V.B. Schini, and P.M. Vanhoutte L-arginine evokes both endothelium-dependent and -independent relaxations in L-arginine-depleted aortas of the rat Circ. Res. 68 1991 209 216
37. G.L. Smith, C. Austin, C. Crichton, and S. Wray A review of the actions and control of intracellular pH in vascular smooth muscle Cardiovasc. Res. 38 1998 316 331 (Pubitemid 28294149)
38. + channel modulation in arterial smooth muscle Acta Physiol. Scand. 164 1998 549 557 (Pubitemid 29015673)
39. G. Subramaniam, F.I. Achike, and M.R. Mustafa Effect of acidosis on the mechanism(s) of insulin-induced vasorelaxation in normal Wistar-Kyoto (WKY) rat aorta Regul. Pept. 155 2009 70 75
40. F. Viaro, A.C. Celotto, V.K. Capellini, C.F. Baldo, A.J. Rodrigues, W.V. Vicente, and P.R. Evora Compound 48/80 induces endothelium-dependent and histamine release-independent relaxation in rabbit aorta Nitric Oxide 18 2008 87 92
41. Q. Wang, O.B. Paulson, and N.A. Lassen Effect of nitric oxide blockade by NG-nitro-L-arginine on cerebral blood flow response to changes in carbon dioxide tension J. Cereb. Blood Flow Metab. 12 1992 947 953
42. M. Yu, C.W. Sun, K.G. Maier, D.R. Harder, and R.J. Roman Mechanism of cGMP contribution to the vasodilator response to NO in rat middle cerebral arteries Am J Physiol Heart Circ Physiol. 282 2002 H1724 H1731