Salmonella Typhi sense host neuroendocrine stress hormones and release the toxin haemolysin e

EMBO Reports

Volumn 12, Issue 3, 2011, Pages 252-258

  Karavolos, Michail H ^a   Bulmer, David M ^a   Spencer, Hannah ^a   Rampioni, Giordano ^b   Schmalen, Ira ^a   Baker, Stephen ^c   Pickard, Derek ^d   Gray, Joe ^a   Fookes, Maria ^d   Winzer, Klaus ^b   Ivens, Alasdair ^d   Dougan, Gordon ^d   Williams, Paul ^b   Khan, C M Anjam ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^c OXFORD UNIVERSITY CLINICAL RESEARCH UNIT   (Viet Nam)

^d WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

cpx; haemolysin; hormones; micA; Salmonella

Indexed keywords

HEMOLYSIN; HEMOLYSIN E; OUTER MEMBRANE PROTEIN A; PROPRANOLOL; STRESS HORMONE; UNCLASSIFIED DRUG;

ARTICLE; DOWN REGULATION; GENE EXPRESSION; HEMOLYSIS; HORMONE RELEASE; HORMONE RESPONSE; HOST; MEMBRANE VESICLE; NEUROENDOCRINE SYSTEM; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SALMONELLA TYPHI; SIGNAL TRANSDUCTION;

BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL PROTEINS; DOWN-REGULATION; EPINEPHRINE; GENE EXPRESSION REGULATION, BACTERIAL; HEMOLYSIN PROTEINS; HEMOLYSIS; HORMONES; NOREPINEPHRINE; PROPRANOLOL; PROTEIN KINASES; SALMONELLA TYPHI; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL;

SALMONELLA; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHI; SALMONELLA TYPHI;

EID: 79952280202     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/embor.2011.4     Document Type: Article

References (24)

1. Bearson BL, Bearson SMD (2008) The role of the QseC quorum-sensing sensor kinase in colonization and norepinephrine-enhanced motility of Salmonella enterica serovar Typhimurium. Microb Pathog 44: 271-278 (Pubitemid 351389740)
2. Chatfield SN, Strahan K, Pickard D, Charles IG, Hormaeche CE, Dougan G (1992) Evaluation of Salmonella typhimurium strains harbouring defined mutations in htrA and aroA in the murine salmonellosis model. Microb Pathog 12: 145-151
3. Datsenko KA, Wanner BL (2000) One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci USA 97: 6640-6645 (Pubitemid 30412767)
4. Flierl MA et al (2007) Phagocyte-derived catecholamines enhance acute inflammatory injury. Nature 449: 721-725 (Pubitemid 47552095)
5. Flierl MA, Rittirsch D, Nadeau BA, Sarma JV, Day DE, Lentsch AB, Huber-Lang MS, Ward PA (2009) Upregulation of phagocyte-derived catecholamines augments the acute inflammatory response. PLoS ONE 4: e4414
6. Fuentes JA, Villagra N, Castillo-Ruiz M, Mora GC (2008) The Salmonella Typhi hlyE gene plays A role in invasion of cultured epithelial cells and its functional transfer to S. Typhimurium promotes deep organ infection in mice. Res Microbiol 159: 279-287
7. Furness JB (2000) Types of neurons in the enteric nervous system. J Auton Nerv Sys 81: 87-96 (Pubitemid 30408484)
8. Huang DB, DuPont HL (2005) Problem pathogens: extra-intestinal complications of Salmonella enterica serotype Typhi infection. Lancet Infect Dis 5: 341-348 (Pubitemid 40779255)
9. Humphreys S, Rowley G, Stevenson A, Anjum MF, Woodward MJ, Gilbert S, Kormanec J, Roberts M (2004) Role of the two-component regulator CpxAR in the virulence of Salmonella enterica serotype typhimurium. Infect Immun 72: 4654-4661 (Pubitemid 38989325)
10. Karavolos MH, Spencer H, Bulmer DM, Thompson A, Winzer K, Williams P, Hinton JCD, Khan CA (2008) Adrenaline modulates the global transcriptional profile of Salmonella revealing A role in the antimicrobial peptide and oxidative stress resistance responses. BMC Genomics 9: 458
11. Mashburn-Warren L, Howe J, Garidel P, Richter W, Steiniger F, Roessle M, Brandenburg K, Whiteley M (2008) Interaction of quorum signals with outer membrane lipids: insights into prokaryotic membrane vesicle formation. Mol Microbiol 69: 491-502 (Pubitemid 351988019)
12. Mashburn-Warren L, Howe J, Brandenburg K, Whiteley M (2009) Structural requirements of the pseudomonas quinolone signal for membrane vesicle stimulation. J Bacteriol 191: 3411-3414
13. MeRIGhi M, Septer A, Carroll-Portillo A, Bhatiya A, Porwollik S, McClelland M, Gunn J (2009) Genome-wide analysis of the PreA/PreB (QseB/QseC) Regulon of Salmonella enterica serovar Typhimurium. BMC Microbiol 9: 42
14. Pacheco AR, Sperandio V (2009) Inter-kingdom signaling: chemical language between bacteria and host. Curr Opin Microbiol 12: 192-198
15. Pullinger GD, Carnell SC, Sharaff FF, Van Diemen PM, Dziva F, Morgan E, Lyte M, Freestone PPE, Stevens MP (2010) Norepinephrine augments salmonella enterica-induced enteritis in A manner associated with increased net replication but independent of the putative adrenergic sensor kinases QseC and QseE. Infect Immun 78: 372-380
16. Rasko DA et al (2008) Targeting QseC signaling and virulence for antibiotic development. Science 321: 1078-1080
17. Sittka A, Pfeiffer V, Tedin K, Vogel J (2007) The RNA chaperone Hfq is essential for the virulence of Salmonella typhimurium. Mol Microbiol 63: 193-217 (Pubitemid 44968119)
18. Spencer H, Karavolos MH, Bulmer DM, Aldridge P, Chhabra SR, Winzer K, Williams P, Khan CMA (2010) Genome-wide transposon mutagenesis identifies A role for host neuroendocrine stress hormones in regulating the expression of virulence genes in S. Typhimurium. J Bacteriol 192: 714-724
19. Udekwu KI, Darfeuille F, Vogel J, Reimegard J, Holmqvist E, Wagner EG (2005) Hfq-dependent regulation of OmpA synthesis is mediated by an antisense RNA. Genes Dev 19: 2355-2366 (Pubitemid 41396912)
20. Von Rhein C, Bauer S, López Sanjurjo EJ, Benz R, Goebel W, Ludwig A (2009) ClyA cytolysin from Salmonella: distribution within the genUS, Regulation of expression by SlYA, and pore-forming characteristics. Inter J Med Microbiol 299: 21-35
21. Vytvytska O, Moll I, Kaberdin VR, Von Gabain A, Bläsi U (2000) Hfq (HF1) Stimulates ompA mRNA decay by interfering with ribosome binding. Genes Devel 14: 1109-1118 (Pubitemid 30324424)
22. Wai SN, Lindmark B, Söderblom T, Takade A, Westermark M, Oscarsson J, Jass J, Richter-Dahlfors A, Mizunoe Y, Uhlin BE (2003) Vesicle-mediated Export and assembly of pore-forming oligomers of the enterobacterial ClyA cytotoxin. Cell 115: 25-35 (Pubitemid 37255315)
23. Wang Y (2002) The function of OmpA in Escherichia coli. Biochem Biophys Res Commun 292: 396-401 (Pubitemid 34694277)
24. Williams P (2007) Quorum sensing, Communication and cross-kingdom signalling in the bacterial world. Microbiology 153: 3923-3938