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Volumn 10, Issue 6, 2010, Pages 465-470

Phase II study of bortezomib and pegylated liposomal doxorubicin in the treatment of metastatic breast cancer

Author keywords

Dexamethasone; Liver metastases; Ondansetron; Proteasome inhibitor; Pyridoxine; Ranitidine

Indexed keywords

BORTEZOMIB; DEXAMETHASONE; DIPHENHYDRAMINE; DOXORUBICIN; MANNITOL; ONDANSETRON; PYRIDOXINE; RANITIDINE; ANTINEOPLASTIC AGENT; BORONIC ACID DERIVATIVE; DRUG DERIVATIVE; MACROGOL DERIVATIVE; PYRAZINE DERIVATIVE;

EID: 79952277119     PISSN: 15268209     EISSN: 19380666     Source Type: Journal    
DOI: 10.3816/CBC.2010.n.061     Document Type: Article
Times cited : (25)

References (52)
  • 1
    • 37249026703 scopus 로고    scopus 로고
    • Intracellular protein degradation from a vague idea through the lysosome and the ubiquitin-proteasome system and on to human diseases and drug targeting: Nobel lecture, December 8, 2004
    • DOI 10.1196/annals.1402.078, Skeletal Biology and Medicine, Part A: Aspects of Bone Morphogenesis and Remodeling
    • Ciechanover A. Intracellular protein degradation from a vague idea through the lysosome and the ubiquitin-proteasome system and on to human diseases and drug targeting: Nobel Lecture, December 8, 2004. Ann N Y Acad Sci 2007; 1116: 1-28. (Pubitemid 350274349)
    • (2007) Annals of the New York Academy of Sciences , vol.1116 , pp. 1-28
    • Ciechanover, A.1
  • 8
    • 11144231029 scopus 로고    scopus 로고
    • Intermittent hypoxia induces proteasome-dependent down-regulation of estrogen receptor α in human breast carcinoma
    • DOI 10.1158/1078-0432.CCR-04-1235
    • Cooper C, Liu GY, Niu YL, et al. Intermittent hypoxia induces proteasomedependent down-regulation of estrogen receptor alpha in human breast carcinoma. Clin Cancer Res 2004; 10: 8720-7. (Pubitemid 40053441)
    • (2004) Clinical Cancer Research , vol.10 , Issue.24 , pp. 8720-8727
    • Cooper, C.1    Liu, G.-Y.2    Niu, Y.-L.3    Santos, S.4    Murphy, L.C.5    Watson, P.H.6
  • 9
    • 33645470112 scopus 로고    scopus 로고
    • Differential cellular and molecular effects of bortezomib, a proteasome inhibitor, in human breast cancer cells
    • Codony-Servat J, Tapia MA, Bosch M, et al. Differential cellular and molecular effects of bortezomib, a proteasome inhibitor, in human breast cancer cells. Mol Cancer Ther 2006; 5: 665-75.
    • (2006) Mol Cancer Ther , vol.5 , pp. 665-675
    • Codony-Servat, J.1    Tapia, M.A.2    Bosch, M.3
  • 12
    • 33646186160 scopus 로고    scopus 로고
    • Bortezomib (VELCADE) in metastatic breast cancer: Pharmacodynamics, biological effects, and prediction of clinical benefits
    • Yang CH, Gonzalez-Angulo AM, Reuben JM, et al. Bortezomib (VELCADE) in metastatic breast cancer: pharmacodynamics, biological effects, and prediction of clinical benefits. Ann Oncol 2006; 17: 813-7.
    • (2006) Ann Oncol , vol.17 , pp. 813-817
    • Yang, C.H.1    Gonzalez-Angulo, A.M.2    Reuben, J.M.3
  • 14
    • 41549133200 scopus 로고    scopus 로고
    • Proteasome inhibitors in cancer therapy: Lessons from the first decade
    • DOI 10.1158/1078-0432.CCR-07-2218
    • Orlowski RZ, Kuhn DJ. Proteasome inhibitors in cancer therapy: lessons from the first decade. Clin Cancer Res 2008; 14: 1649-57. (Pubitemid 351469448)
    • (2008) Clinical Cancer Research , vol.14 , Issue.6 , pp. 1649-1657
    • Orlowski, R.Z.1    Kuhn, D.J.2
  • 16
    • 0344737064 scopus 로고    scopus 로고
    • Repression of Mitogen-Activated Protein Kinase (MAPK) Phosphatase-1 by Anthracyclines Contributes to Their Antiapoptotic Activation of p44/42-MAPK
    • DOI 10.1124/jpet.103.055806
    • Small GW, Somasundaram S, Moore DT, et al. Repression of mitogen-activated protein kinase (MAPK) phosphatase-1 by anthracyclines contributes to their antiapoptotic activation of p44/42-MAPK. J Pharmacol Exp Ther 2003; 307: 861-9. (Pubitemid 37494202)
    • (2003) Journal of Pharmacology and Experimental Therapeutics , vol.307 , Issue.3 , pp. 861-869
    • Small, G.W.1    Somasundaram, S.2    Moore, D.T.3    Shi, Y.Y.4    Orlowski, R.Z.5
  • 17
    • 0037008780 scopus 로고    scopus 로고
    • Evidence that inhibition of p44/42 mitogen-activated protein kinase signaling is a factor in proteasome inhibitor-mediated apoptosis
    • DOI 10.1074/jbc.M201519200
    • Orlowski RZ, Small GW, Shi YY. Evidence that inhibition of p44/42 mitogenactivated protein kinase signaling is a factor in proteasome inhibitor-mediated apoptosis. J Biol Chem 2002; 277: 27864-71. (Pubitemid 34966732)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.31 , pp. 27864-27871
    • Orlowski, R.Z.1    Small, G.W.2    Shi, Y.Y.3
  • 18
    • 9444249941 scopus 로고    scopus 로고
    • Evidence that mitogen-activated protein kinase phosphatase-1 induction by proteasome inhibitors plays an antiapoptotic role
    • DOI 10.1124/mol.104.003400
    • Small GW, Shi YY, Edmund NA, et al. Evidence that mitogen-activated protein kinase phosphatase-1 induction by proteasome inhibitors plays an antiapoptotic role. Mol Pharmacol 2004; 66: 1478-90. (Pubitemid 39564774)
    • (2004) Molecular Pharmacology , vol.66 , Issue.6 , pp. 1478-1490
    • Small, G.W.1    Shi, Y.Y.2    Edmund, N.A.3    Somasundaram, S.4    Moore, D.T.5    Orlowski, R.Z.6
  • 19
    • 34249062137 scopus 로고    scopus 로고
    • Proteasome inhibitors induce a p38 mitogenactivated protein kinase (MAPK)-dependent anti-apoptotic program involving MAPK phosphatase-1 and Akt in models of breast cancer
    • Shi YY, Small GW, Orlowski RZ. Proteasome inhibitors induce a p38 mitogenactivated protein kinase (MAPK)-dependent anti-apoptotic program involving MAPK phosphatase-1 and Akt in models of breast cancer. Breast Cancer Res Treat 2006; 100: 33-47.
    • (2006) Breast Cancer Res Treat , vol.100 , pp. 33-47
    • Shi, Y.Y.1    Small, G.W.2    Orlowski, R.Z.3
  • 20
    • 0030959798 scopus 로고    scopus 로고
    • Treatment of advanced breast cancer with sterically stabilized liposomal doxorubicin: Results of a multicenter phase II trial
    • Ranson MR, Carmichael J, O'Byrne K, et al. Treatment of advanced breast cancer with sterically stabilized liposomal doxorubicin: results of a multicenter phase II trial. J Clin Oncol 1997; 15: 3185-91. (Pubitemid 27419330)
    • (1997) Journal of Clinical Oncology , vol.15 , Issue.10 , pp. 3185-3191
    • Ranson, M.R.1    Carmichael, J.2    O'Byrne, K.3    Stewart, S.4    Smith, D.5    Howell, A.6
  • 22
    • 0034284335 scopus 로고    scopus 로고
    • Correlation of toxicity with pharmacokinetics of pegylated liposomal doxorubicin (Doxil) in metastatic breast carcinoma
    • Lyass O, Uziely B, Ben-Yosef R, et al. Correlation of toxicity with pharmacokinetics of pegylated liposomal doxorubicin (Doxil) in metastatic breast carcinoma. Cancer 2000; 89: 1037-47.
    • (2000) Cancer , vol.89 , pp. 1037-1047
    • Lyass, O.1    Uziely, B.2    Ben-Yosef, R.3
  • 23
    • 20144387627 scopus 로고    scopus 로고
    • Phase 1 trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies
    • Orlowski RZ, Voorhees PM, Garcia RA, et al. Phase 1 trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies. Blood 2005; 105: 3058-65.
    • (2005) Blood , vol.105 , pp. 3058-3065
    • Orlowski, R.Z.1    Voorhees, P.M.2    Garcia, R.A.3
  • 24
    • 33846691618 scopus 로고    scopus 로고
    • Extended follow-up of outcome measures in multiple myeloma patients treated on a phase I study with bortezomib and pegylated liposomal doxorubicin
    • DOI 10.1007/s00277-006-0220-3
    • Biehn SE, Moore DT, Voorhees PM, et al. Extended follow-up of outcome measures in multiple myeloma patients treated on a phase I study with bortezomib and pegylated liposomal doxorubicin. Ann Hematol 2007; 86: 211-6. (Pubitemid 46195994)
    • (2007) Annals of Hematology , vol.86 , Issue.3 , pp. 211-216
    • Biehn, S.E.1    Moore, D.T.2    Voorhees, P.M.3    Garcia, R.A.4    Lehman, M.J.5    Dees, C.E.6    Orlowski, R.Z.7
  • 26
    • 53149115608 scopus 로고    scopus 로고
    • A phase i and pharmacologic study of the combination of bortezomib and pegylated liposomal doxorubicin in patients with refractory solid tumors
    • Dees EC, O'Neil BH, Lindley CM, et al. A phase I and pharmacologic study of the combination of bortezomib and pegylated liposomal doxorubicin in patients with refractory solid tumors. Cancer Chemother Pharmacol 2008; 63: 99-107.
    • (2008) . Cancer Chemother Pharmacol , vol.63 , pp. 99-107
    • Dees, E.C.1    O'neil, B.H.2    Lindley, C.M.3
  • 27
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
    • Therasse P, Arbuck SG, Eisenhauer EA, et al. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 2000; 92: 205-16.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3
  • 28
    • 62449131093 scopus 로고    scopus 로고
    • Supervised risk predictor of breast cancer based on intrinsic subtypes
    • Parker JS, Mullins M, Cheang MC, et al. Supervised risk predictor of breast cancer based on intrinsic subtypes. J Clin Oncol 2009; 27: 1160-7.
    • (2009) J Clin Oncol , vol.27 , pp. 1160-1167
    • Parker, J.S.1    Mullins, M.2    Cheang, M.C.3
  • 29
    • 0024536437 scopus 로고
    • Optimal two-stage designs for phase II clinical trials
    • DOI 10.1016/0197-2456(89)90015-9
    • Simon R. Optimal two-stage designs for phase II clinical trials. Control Clin Trials 1989; 10: 1-10. (Pubitemid 19099520)
    • (1989) Controlled Clinical Trials , vol.10 , Issue.1 , pp. 1-10
    • Simon, R.1
  • 30
    • 49549114644 scopus 로고    scopus 로고
    • Phase i study of bortezomib with weekly paclitaxel in patients with advanced solid tumours
    • Cresta S, Sessa C, Catapano CV, et al. Phase I study of bortezomib with weekly paclitaxel in patients with advanced solid tumours. Eur J Cancer 2008; 44: 1829-34.
    • (2008) Eur J Cancer , vol.44 , pp. 1829-1834
    • Cresta, S.1    Sessa, C.2    Catapano, C.V.3
  • 32
    • 43249103125 scopus 로고    scopus 로고
    • Bortezomib/docetaxel combination therapy in patients with anthracycline-pretreated advanced/metastatic breast cancer: A phase I/II dose-escalation study
    • DOI 10.1038/sj.bjc.6604347, PII 6604347
    • Awada A, Albanell J, Canney PA, et al. Bortezomib/docetaxel combination therapy in patients with anthracycline-pretreated advanced/metastatic breast cancer: a phase I/II dose-escalation study. Br J Cancer 2008; 98: 1500-7. (Pubitemid 351652337)
    • (2008) British Journal of Cancer , vol.98 , Issue.9 , pp. 1500-1507
    • Awada, A.1    Albanell, J.2    Canney, P.A.3    Dirix, L.Y.4    Gil, T.5    Cardoso, F.6    Gascon, P.7    Piccart, M.J.8    Baselga, J.9
  • 33
    • 3042622482 scopus 로고    scopus 로고
    • HER2 amplification ratios by fluorescence in situ hybridization and correlation with immunohistochemistry in a cohort of 6556 breast cancer tissues
    • Owens MA, Horten BC, Da Silva MM. HER2 amplification ratios by fluorescence in situ hybridization and correlation with immunohistochemistry in a cohort of 6556 breast cancer tissues. Clin Breast Cancer 2004; 5: 63-9. (Pubitemid 38821193)
    • (2004) Clinical Breast Cancer , vol.5 , Issue.1 , pp. 63-69
    • Owens, M.A.1    Horten, B.C.2    Da Silva, M.M.3
  • 37
    • 0035805582 scopus 로고    scopus 로고
    • The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation
    • Hashizume R, Fukuda M, Maeda I, et al. The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation. J Biol Chem 2001; 276: 14537-40.
    • (2001) J Biol Chem , vol.276 , pp. 14537-14540
    • Hashizume, R.1    Fukuda, M.2    Maeda, I.3
  • 39
    • 0032513215 scopus 로고    scopus 로고
    • Proteasome inhibitors activate stress kinases and induce Hsp72. Diverse effects on apoptosis
    • DOI 10.1074/jbc.273.11.6373
    • Meriin AB, Gabai VL, Yaglom J, et al. Proteasome inhibitors activate stress kinases and induce Hsp72. Diverse effects on apoptosis. J Biol Chem 1998; 273: 6373-9. (Pubitemid 28144729)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.11 , pp. 6373-6379
    • Meriin, A.B.1    Gabai, V.L.2    Yaglom, J.3    Shifrin, V.I.4    Sherman, M.Y.5
  • 40
    • 1642486367 scopus 로고    scopus 로고
    • Proteasome inhibitor PS-341 induces growth arrest and apoptosis of non-small cell lung cancer cells via the JNK/c-Jun/AP-1 signaling
    • DOI 10.1111/j.1349-7006.2004.tb03200.x
    • Yang Y, Ikezoe T, Saito T, et al. Proteasome inhibitor PS-341 induces growth arrest and apoptosis of non-small cell lung cancer cells via the JNK/c-Jun/AP-1 signaling. Cancer Sci 2004; 95: 176-80. (Pubitemid 38404320)
    • (2004) Cancer Science , vol.95 , Issue.2 , pp. 176-180
    • Yang, Y.1    Ikezoe, T.2    Saito, T.3    Kobayashi, M.4    Koeffler, H.P.5    Taguchi, H.6
  • 42
    • 0028924419 scopus 로고
    • Role of mitogen-activated protein kinase phosphatase during the cellular response to genotoxic stress. Inhibition of c-Jun N-terminal kinase activity and AP-1-dependent gene activation
    • Liu Y, Gorospe M, Yang C, et al. Role of mitogen-activated protein kinase phosphatase during the cellular response to genotoxic stress. Inhibition of c-Jun N-terminal kinase activity and AP-1-dependent gene activation. J Biol Chem 1995; 270: 8377-80.
    • (1995) J Biol Chem , vol.270 , pp. 8377-8380
    • Liu, Y.1    Gorospe, M.2    Yang, C.3
  • 43
    • 0032539919 scopus 로고    scopus 로고
    • Conditional expression of mitogen-activated protein kinase phosphatase-1, MKP-1, is cytoprotective against UV-induced apoptosis
    • Franklin CC, Srikanth S, Kraft AS. Conditional expression of mitogen-activated protein kinase phosphatase-1, MKP-1, is cytoprotective against UV-induced apoptosis. Proc Natl Acad Sci USA 1998; 95: 3014-9.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 3014-3019
    • Franklin, C.C.1    Srikanth, S.2    Kraft, A.S.3
  • 44
    • 0032562781 scopus 로고    scopus 로고
    • Inhibition of the expression of mitogen-activated protein phosphatase-1 potentiates apoptosis induced by tumor necrosis factor-α in rat mesangial cells
    • DOI 10.1074/jbc.273.17.10362
    • Guo YL, Kang B, Williamson JR. Inhibition of the expression of mitogenactivated protein phosphatase-1 potentiates apoptosis induced by tumor necrosis factor-alpha in rat mesangial cells. J Biol Chem 1998; 273: 10362-6. (Pubitemid 28227643)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.17 , pp. 10362-10366
    • Guo, Y.-L.1    Kang, B.2    Williamson, J.R.3
  • 45
    • 43049101029 scopus 로고    scopus 로고
    • Dual-specificity MAP kinase phosphatases (MKPs) and cancer
    • Keyse SM. Dual-specificity MAP kinase phosphatases (MKPs) and cancer. Cancer Metastasis Rev 2008; 27: 253-61.
    • (2008) Cancer Metastasis Rev , vol.27 , pp. 253-261
    • Keyse, S.M.1
  • 46
    • 0037606170 scopus 로고    scopus 로고
    • Down-regulation of the dual-specificity phosphatase MKP-1 suppresses tumorigenicity of pancreatic cancer cells
    • DOI 10.1016/S0016-5085(03)00398-6
    • Liao Q, Guo J, Kleeff J, et al. Down-regulation of the dual-specificity phosphatase MKP-1 suppresses tumorigenicity of pancreatic cancer cells. Gastroenterology 2003; 124: 1830-45. (Pubitemid 36666779)
    • (2003) Gastroenterology , vol.124 , Issue.7 , pp. 1830-1845
    • Liao, Q.1    Guo, J.2    Kleeff, J.3    Zimmermann, A.4    Buchler, M.W.5    Korc, M.6    Friess, H.7
  • 47
    • 66149167313 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase phosphatase-1 in human breast cancer independently predicts prognosis and is repressed by doxorubicin
    • Rojo F, Gonzalez-Navarrete I, Bragado R, et al. Mitogen-activated protein kinase phosphatase-1 in human breast cancer independently predicts prognosis and is repressed by doxorubicin. Clin Cancer Res 2009; 15: 3530-9.
    • (2009) Clin Cancer Res , vol.15 , pp. 3530-3539
    • Rojo, F.1    Gonzalez-Navarrete, I.2    Bragado, R.3
  • 49
    • 0037430452 scopus 로고    scopus 로고
    • Overexpression of mitogen-activated protein kinase phosphatases MKP1, MKP2 in human breast cancer
    • DOI 10.1016/S0304-3835(02)00612-2
    • Wang HY, Cheng Z, Malbon CC. Overexpression of mitogen-activated protein kinase phosphatases MKP1, MKP2 in human breast cancer. Cancer Lett 2003; 191: 229-37. (Pubitemid 36255609)
    • (2003) Cancer Letters , vol.191 , Issue.2 , pp. 229-237
    • Wang, H.-Y.1    Cheng, Z.2    Malbon, C.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.