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Treatment of multiple myeloma
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Barlogie B, Shaughnessy JD, Tricot G, Jacobson J, Zangari M, Anaissie E, Walker R, Crowley J (2004) Treatment of multiple myeloma. Blood 103:20-32
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Barlogie, B.1
Shaughnessy, J.D.2
Tricot, G.3
Jacobson, J.4
Zangari, M.5
Anaissie, E.6
Walker, R.7
Crowley, J.8
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2
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33644916110
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Phase I/II trial assessing bortezomib and melphalan combination therapy for the treatment of patients with relapsed or refractory multiple myeloma
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Berenson JR, Yang HH, Sadler K, Jarutirasarn SG, Vescio RA, Mapes R, Purner M, Lee SP, Wilson J, Morrison B, Adams J, Schenkein D, Swift R (2006) Phase I/II trial assessing bortezomib and melphalan combination therapy for the treatment of patients with relapsed or refractory multiple myeloma. J Clin Oncol 24:937-944
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J Clin Oncol
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Berenson, J.R.1
Yang, H.H.2
Sadler, K.3
Jarutirasarn, S.G.4
Vescio, R.A.5
Mapes, R.6
Purner, M.7
Lee, S.P.8
Wilson, J.9
Morrison, B.10
Adams, J.11
Schenkein, D.12
Swift, R.13
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3
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18244428600
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Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic stem cell transplantation. Myeloma Subcommittee of the EBMT. European Group for Blood and Marrow Transplant
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Bladé J, Samson D, Reece D, Apperley J, Bjorkstrand B, Gahrton G, Gertz M, Giralt S, Jagannath S, Vesole D (1998) Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic stem cell transplantation. Myeloma Subcommittee of the EBMT. European Group for Blood and Marrow Transplant. Br J Haematol 102:1115-1123
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Bladé, J.1
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Apperley, J.4
Bjorkstrand, B.5
Gahrton, G.6
Gertz, M.7
Giralt, S.8
Jagannath, S.9
Vesole, D.10
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4
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0035300479
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The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells
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Hideshima T, Richardson P, Chauhan D, Palombella VJ, Elliott PJ, Adams J, Anderson KC (2001) The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells. Cancer Res 61:3071-3076
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Cancer Res
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Hideshima, T.1
Richardson, P.2
Chauhan, D.3
Palombella, V.J.4
Elliott, P.J.5
Adams, J.6
Anderson, K.C.7
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5
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0037342894
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The proteasome inhibitor PS-341 markedly enhances sensitivity of multiple myeloma tumor cells to chemotherapeutic agents
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Ma MH, Yang HH, Parker K, Manyak S, Friedman JM, Altamirano C, Wu ZQ, Borad MJ, Frantzen M, Roussos E, Neeser J, Mikail A, Adams J, Sjak-Shie N, Vescio RA, Berenson JR (2003) The proteasome inhibitor PS-341 markedly enhances sensitivity of multiple myeloma tumor cells to chemotherapeutic agents. Clin Cancer Res 9:1136-1144
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Clin Cancer Res
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Ma, M.H.1
Yang, H.H.2
Parker, K.3
Manyak, S.4
Friedman, J.M.5
Altamirano, C.6
Wu, Z.Q.7
Borad, M.J.8
Frantzen, M.9
Roussos, E.10
Neeser, J.11
Mikail, A.12
Adams, J.13
Sjak-Shie, N.14
Vescio, R.A.15
Berenson, J.R.16
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6
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0037443551
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The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: Therapeutic applications
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Mitsiades N, Mitsiades CS, Richardson PG, Poulaki V, Tai YT, Chauhan D, Fanourakis G, Gu X, Bailey C, Joseph M, Libermann TA, Schlossman R, Munshi NC, Hideshima T, Anderson KC (2003) The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: Therapeutic applications. Blood 101:2377-2380
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Mitsiades, N.1
Mitsiades, C.S.2
Richardson, P.G.3
Poulaki, V.4
Tai, Y.T.5
Chauhan, D.6
Fanourakis, G.7
Gu, X.8
Bailey, C.9
Joseph, M.10
Libermann, T.A.11
Schlossman, R.12
Munshi, N.C.13
Hideshima, T.14
Anderson, K.C.15
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7
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0037111832
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Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies
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Orlowski RZ, Stinchcombe TE, Mitchell BS, Shea TC, Baldwin AS, Stahl S, Adams J, Esseltine DL, Elliott PJ, Pien CS, Guerciolini R, Anderson JK, Depcik-Smith ND, Bhagat R, Lehman MJ, Novick SC, O'Connor OA, Soignet SL (2002) Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies. J Clin Oncol 20:4420-4427
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J Clin Oncol
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Orlowski, R.Z.1
Stinchcombe, T.E.2
Mitchell, B.S.3
Shea, T.C.4
Baldwin, A.S.5
Stahl, S.6
Adams, J.7
Esseltine, D.L.8
Elliott, P.J.9
Pien, C.S.10
Guerciolini, R.11
Anderson, J.K.12
Depcik-Smith, N.D.13
Bhagat, R.14
Lehman, M.J.15
Novick, S.C.16
O'Connor, O.A.17
Soignet, S.L.18
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8
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20144387627
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Phase 1 trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies
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Orlowski RZ, Voorhees PM, Garcia RA, Hall MD, Kudrik FJ, Allred T, Johri AR, Jones PE, Ivanova A, Van Deventer HW, Gabriel DA, Shea TC, Mitchell BS, Adams J, Esseltine DL, Trehu EG, Green M, Lehman MJ, Natoli S, Collins JM, Lindley CM, Dees EC (2005) Phase 1 trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies. Blood 105:3058-3065
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Blood
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Orlowski, R.Z.1
Voorhees, P.M.2
Garcia, R.A.3
Hall, M.D.4
Kudrik, F.J.5
Allred, T.6
Johri, A.R.7
Jones, P.E.8
Ivanova, A.9
Van Deventer, H.W.10
Gabriel, D.A.11
Shea, T.C.12
Mitchell, B.S.13
Adams, J.14
Esseltine, D.L.15
Trehu, E.G.16
Green, M.17
Lehman, M.J.18
Natoli, S.19
Collins, J.M.20
Lindley, C.M.21
Dees, E.C.22
more..
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9
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0037973279
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A phase 2 study of bortezomib in relapsed, refractory myeloma
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Richardson PG, Barlogie B, Berenson J, Singhal S, Jagannath S, Irwin D, Rajkumar SV, Srkalovic G, Alsina M, Alexanian R, Siegel D, Orlowski RZ, Kuter D, Limentani SA, Lee S, Hideshima T, Esseltine DL, Kauffman M, Adams J, Schenkein DP, Anderson KC (2003) A phase 2 study of bortezomib in relapsed, refractory myeloma. N Engl J Med 348:2609-2617
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N Engl J Med
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Richardson, P.G.1
Barlogie, B.2
Berenson, J.3
Singhal, S.4
Jagannath, S.5
Irwin, D.6
Rajkumar, S.V.7
Srkalovic, G.8
Alsina, M.9
Alexanian, R.10
Siegel, D.11
Orlowski, R.Z.12
Kuter, D.13
Limentani, S.A.14
Lee, S.15
Hideshima, T.16
Esseltine, D.L.17
Kauffman, M.18
Adams, J.19
Schenkein, D.P.20
Anderson, K.C.21
more..
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10
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20444433230
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Bortezomib or high-dose dexamethasone for relapsed multiple myeloma
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Richardson PG, Sonneveld P, Schuster MW, Irwin D, Stadtmauer EA, Facon T, Harousseau JL, Ben-Yehuda D, Lonial S, Goldschmidt H, Reece D, San-Miguel JF, Bladé J, Boccadoro M, Cavenagh J, Dalton WS, Boral AL, Esseltine DL, Porter JB, Schenkein D, Anderson KC (2005) Bortezomib or high-dose dexamethasone for relapsed multiple myeloma. N Engl J Med 352:2487-2498
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Richardson, P.G.1
Sonneveld, P.2
Schuster, M.W.3
Irwin, D.4
Stadtmauer, E.A.5
Facon, T.6
Harousseau, J.L.7
Ben-Yehuda, D.8
Lonial, S.9
Goldschmidt, H.10
Reece, D.11
San-Miguel, J.F.12
Bladé, J.13
Boccadoro, M.14
Cavenagh, J.15
Dalton, W.S.16
Boral, A.L.17
Esseltine, D.L.18
Porter, J.B.19
Schenkein, D.20
Anderson, K.C.21
more..
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11
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27644476353
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Clinical factors predictive of outcome with bortezomib in patients with relapsed, refractory multiple myeloma
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Richardson PG, Barlogie B, Berenson J, Singhal S, Jagannath S, Irwin D, Rajkumar SV, Hideshima T, Xiao H, Esseltine D, Schenkein D, Anderson KC (2005) Clinical factors predictive of outcome with bortezomib in patients with relapsed, refractory multiple myeloma. Blood 106:2977-2981
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(2005)
Blood
, vol.106
, pp. 2977-2981
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Richardson, P.G.1
Barlogie, B.2
Berenson, J.3
Singhal, S.4
Jagannath, S.5
Irwin, D.6
Rajkumar, SV.7
Hideshima, T.8
Xiao, H.9
Esseltine, D.10
Schenkein, D.11
Anderson, K.C.12
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12
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33644844108
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Extended follow-up of a phase II trial in relapsed, refractory multiple myeloma: Final time-to-event results from the SUMMIT trial
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Richardson PG, Barlogie B, Berenson J, Singhal S, Jagannath S, Irwin DH, Rajkumar SV, Srkalovic G, Alsina M, Anderson KC (2006) Extended follow-up of a phase II trial in relapsed, refractory multiple myeloma: final time-to-event results from the SUMMIT trial. Cancer 106:1316-1319
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(2006)
Cancer
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, pp. 1316-1319
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Richardson, P.G.1
Barlogie, B.2
Berenson, J.3
Singhal, S.4
Jagannath, S.5
Irwin, D.H.6
Rajkumar, S.V.7
Srkalovic, G.8
Alsina, M.9
Anderson, K.C.10
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13
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9444249941
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Evidence that mitogen-activated protein kinase phosphatase-1 induction by proteasome inhibitors plays an antiapoptotic role
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Small GW, Shi YY, Edmund NA, Somasundaram S, Moore DT, Orlowski RZ (2004) Evidence that mitogen-activated protein kinase phosphatase-1 induction by proteasome inhibitors plays an antiapoptotic role. Mol Pharmacol 66:1478-1490
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(2004)
Mol Pharmacol
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Small, G.W.1
Shi, Y.Y.2
Edmund, N.A.3
Somasundaram, S.4
Moore, D.T.5
Orlowski, R.Z.6
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14
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33746340326
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VELCADE-Thalidomide (T)-Dexamethasone for advanced and refractory multiple myeloma: Long-term follow-up of phase I-II trial UARK 2001-37: Superior outcome in patients with normal cytogenetics and no prior T
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Abstract 2552
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Zangari M, Barlogie B, Burns MJ, Bolejack V, Hollmig KA, van Rhee F, Pineda-Roman M, Elice F, Tricot GJ (2005) VELCADE-Thalidomide (T)-Dexamethasone for advanced and refractory multiple myeloma: long-term follow-up of phase I-II trial UARK 2001-37: Superior outcome in patients with normal cytogenetics and no prior T. Blood 106:ABstract 2552
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(2005)
Blood
, vol.106
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Zangari, M.1
Barlogie, B.2
Burns, M.J.3
Bolejack, V.4
Hollmig, K.A.5
van Rhee, F.6
Pineda-Roman, M.7
Elice, F.8
Tricot, G.J.9
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