Using BLAST to teach "E-value-tionary" concepts

PLoS Biology

Volumn 9, Issue 2, 2011, Pages

  Kerfeld, Cheryl A ^a,b   Scott, Kathleen M ^c  

^a DOE JOINT GENOME INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BIOINFORMATICS; EVOLUTIONARY ALGORITHM; INFORMATION RETRIEVAL; INFORMATION TECHNOLOGY; MATHEMATICAL COMPUTING; MOLECULAR EVOLUTION; NUCLEOTIDE SEQUENCE; SEARCH ENGINE; SEQUENCE ALIGNMENT; SEQUENCE DATABASE; SEQUENCE HOMOLOGY; ALGORITHM; BIOLOGY; COMPUTER PROGRAM; MOLECULAR GENETICS; SEQUENCE ANALYSIS; TEACHING;

ALGORITHMS; AMINO ACID SEQUENCE; COMPUTATIONAL BIOLOGY; EVOLUTION, MOLECULAR; MOLECULAR SEQUENCE DATA; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; SOFTWARE; TEACHING;

EID: 79952267766     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1001014     Document Type: Article

References (4)

1. Altschul S, Madden T, Schaffer A, Zhang J, Zhang Z, et al. (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 25: 3389-3402.
2. Altschul S. F, Gish W, Miller W, Myers E. W, Lipman D. J, (1990) Basic local alignment search tool. J Mol Biol 215: 403-410.
3. Eddy S. R, (2004) Where did the BLOSUM62 alignment score matrix come from? Nature Biotechnol 22: 1035-1036.
4. Henikoff S, Henikoff J. G, (1992) Amino acid substitution matrices from protein blocks. Proc Natl Acad Sci 89: 10915-10919.