Paraneoplastic leukocytosis in a dog with a renal carcinoma

Veterinary Clinical Pathology

Volumn 40, Issue 1, 2011, Pages 89-94

  Petterino, Claudio ^a   Luzio, Elisabetta ^b   Baracchini, Luca ^c   Ferrari, Angelo ^d   Ratto, Alessandra ^d  

^a UNIVERSITY OF PADOVA   (Italy)

^b Studio Veterinario Associato Bertoldi Luzio   (Italy)

^c Studio Veterinario Associato Cuneo Baracchini   (Italy)

^d LIGURIA E VALLE D AOSTA   (Italy)

Author keywords

Chromophobic cystic papillary renal carcinoma; GM CSF; Hematuria; Neutrophilia

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR;

ANIMAL; ANIMAL DISEASE; ARTICLE; CASE REPORT; DOG; DOG DISEASE; FATALITY; KIDNEY; KIDNEY CARCINOMA; KIDNEY TUMOR; LEUKOCYTOSIS; MALE; METABOLISM; PARANEOPLASTIC SYNDROME; PATHOLOGY;

ANIMALS; CARCINOMA, RENAL CELL; DOG DISEASES; DOGS; FATAL OUTCOME; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; KIDNEY; KIDNEY NEOPLASMS; LEUKOCYTOSIS; MALE; PARANEOPLASTIC SYNDROMES;

CANIS FAMILIARIS;

EID: 79952235579     PISSN: 02756382     EISSN: 1939165X     Source Type: Journal    
DOI: 10.1111/j.1939-165X.2011.00296.x     Document Type: Article

References (20)

1. Peeters D, Clercx C, Thiry A, et al. Resolution of paraneoplastic leukocytosis and hyperthrophic osteopathy after resection of a renal transitional cell carcinoma producing granulocyte-macrophage colony-stimulating factor in a young Bull Terrier. J Vet Intern Med. 2001;15:407-411.
2. Sharkey LC, Rosol TJ, Gröne A, Ward H, Steinmeyer C. Production of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor by carcinomas in a dog and a cat with paraneoplastic leukocytosis. J Vet Intern Med. 1996;10:405-408.
3. Thompson JP, Christopher MM, Ellison GW, Homer BL, Buchanan BA. Paraneoplastic leukocytosis associated with a rectal adenomatous polyp in a dog. J Am Vet Med Assoc. 1992;20:737-738.
4. Lappin MR, Latimer KS. Hematuria and extreme neutrophilic leukocytosis in a dog with renal tubular carcinoma. J Am Vet Med Assoc. 1988;192:1289-1292.
5. Madewell BR, Wilson DW, Hornof WJ, Gregory CR. Leukemoid blood response and bone infarcts in a dog with renal tubular adenocarcinoma. J Am Vet Med Assoc. 1990;197:1623-1625.
6. Chinn DR, Myers RK, Matthews JA. Neutrophilic leukocytosis associated with metastatic fibrosarcoma in a dog. J Am Vet Med Assoc. 1985;186:806-809.
7. Weltan SM, Leisewitz AL, Goddard A. A case-controlled retrospective study of the causes and implications of moderate to severe leukocytosis in dogs in South Africa. Vet Clin Pathol. 2008;37:164-172.
8. Chiang Y-C, Liu C-H, Ho S-Y, Lin C-T. Hypertrophic osteopathy associated with disseminated metastases of renal cell carcinoma in the dog: a case report. J Vet Med Sci. 2007;69:209-212.
9. Battaglia L, Petterino C, Zappulli V, Castagnaro M. Hypoglycemia as a paraneoplastic syndrome associated with renal adenocarcinoma in a dog. Vet Res Commun. 2005;29:671-675.
10. Crow SE, Allen DP, Murphy CJ, Culberston R. Concurrent renal adenocarcinoma and polycythemia in a dog. J Am Anim Hosp Assoc. 1995;31:29-33.
11. Gaunt SD. Extreme neutrophilic leukocytosis. In: Feldman BF, Zinkl JG, Jain N, eds. Schalm's Veterinary Hematology. 5th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2000:347-349.
12. Schultze AE. Interpretation of canine leukocyte responses. In: Feldman BF, Zinkl JG, Jain N, eds. Schalm's Veterinary Hematology. 5th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2000:366-381.
13. Stockham SL, Scott MA. Leukocytes. In: Fundamentals of Clinical Pathology. 2nd ed. Ames, IA: Blackwell; 2008:53-106.
14. O'Keefe DA, Couto CG. Coagulation abnormalities associated with neoplasia. Vet Clin North Am Small Anim Pract. 1988;18:157-68.
15. Maruyama H, Miura T, Sakai M, et al. The incidence of disseminated intravascular coagulation in dogs with malignant tumor. J Vet Med Sci. 2004;66:573-575.
16. Rapaport SI, Rao LVM. The tissue factor pathway: How it has become a 'prima ballerina'. Thromb Haemost. 1995;74:7-17.
17. Iversen N, Lindahl A-K, Abilgaard U. Elevated TFPI in malignant disease: relation to cancer type and hypercoagulation. Br J Haematol. 1998;102:889-895.
18. Edwards RL, Rickles FR, Cronlund M. Abnormalities of blood coagulation in patients with cancer. Mononuclear cell tissue factor generation. J Lab Clin Med. 1981;98:917-928.
19. Stockham SL, Scott MA. Proteins. In: Fundamentals of Clinical Pathology. 2nd ed. Ames, IA: Blackwell Publishing; 2008:369-413.
20. Stockham SL, Scott MA. Calcium, phosphorus, magnesium, and their regulatory hormones. In: Fundamentals of Clinical Pathology. 2nd ed. Ames, IA: Blackwell Publishing; 2002:593-638.