Curcumin as a promising anticandidal of clinical interest

Canadian Journal of Microbiology

Volumn 57, Issue 3, 2011, Pages 204-210

  Neelofar, K ^a   Shreaz, S ^a   Rimple, B ^a   Muralidhar, S ^b   Nikhat, M ^a   Khan, Luqman A ^a  

^a JAMIA MILLIA ISLAMIA CENTRAL UNIVERSITY   (India)

^b SAFDARJUNG HOSPITAL   (India)

Author keywords

Candida; Curcumin; Ergosterol; H+ extrusion; Proteinase

Indexed keywords

ALBICANS; ANTI-FUNGAL ACTIVITY; ANTI-FUNGAL PROPERTIES; ATP-ASE ACTIVITY; CANDIDA ALBICANS; CANDIDA GLABRATA; CURCUMIN; ERGOSTEROL; FLUCONAZOLE; FOOD PREPARATION; H+ EXTRUSION; IN-VITRO; MINIMUM INHIBITORY CONCENTRATION; PLASMA MEMBRANES; PROTEINASE; STANDARD STRAIN;

ALCOHOLS; BIOCHEMISTRY; CANDIDA; CELL MEMBRANES; EXTRUSION; GLUCOSE; PHYSIOLOGY; STANDARDS;

YEAST;

ADENOSINE TRIPHOSPHATASE; CURCUMIN; ERGOSTEROL; FLUCONAZOLE; GLUCOSE; PROTEINASE;

ANTIBIOTICS; ANTIMICROBIAL ACTIVITY; ENZYME ACTIVITY; FUNGAL DISEASE; GLUCOSE; INHIBITOR; SECRETION; SPICE;

ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CANDIDA GLABRATA; CONTROLLED STUDY; DRUG EFFECT; ENZYME RELEASE; FUNGUS GROWTH; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL;

ANTIFUNGAL AGENTS; CANDIDA ALBICANS; CANDIDA GLABRATA; CURCUMIN; ERGOSTEROL; FLUCONAZOLE; GLUCOSE; MICROBIAL SENSITIVITY TESTS; PEPTIDE HYDROLASES; PROTON-TRANSLOCATING ATPASES;

CANDIDA; CANDIDA ALBICANS; CANDIDA GLABRATA;

EID: 79952233526     PISSN: 00084166     EISSN: 14803275     Source Type: Journal    
DOI: 10.1139/W10-117     Document Type: Article

References (26)

1. Ang, B.S.P., Telenti, A., King, B., Steckelberg, J.M., and Wilson, W.R. 1993. Candidemia from a urinary tract source: microbiological aspects and clinical significance. Clin. Infect. Dis. 7: 662-666. PMID:8268347.
2. Breivik, O.N., and Owades, J.L. 1957. Spectrophotometric semimicro determination of ergosterol in yeast. J. Agric. Food Chem. 5(5): 360-363. doi:10.1021/jf60075a005.
3. Conney, A.H., Lysz, T., Ferraro, T., Abidi, T.F., Manchand, P.S., Laskin, J.D., and Huang, M.T. 1991. Inhibitory effect of curcumin and some related dietary compounds on tumor promotion and arachidonic acid metabolism in mouse skin. Adv. Enzyme Regul. 31: 385-396. doi:10.1016/0065-2571(91)90025-H. PMID:1908616.
4. Ghannoum, M.A., and Rice, L.B. 1999. Antifungal agents: mode of action, mechanisms of resistance, and correlation of these mechanisms with bacterial resistance. Clin. Microbiol. Rev. 12(4): 501-517. PMID:10515900.
5. Govindarajan, V.S., and Stahl, W. 1980. Turmeric-chemistry, technology and quality. Crit. Rev. Food Sci. Nutr. 12(3): 199-301. doi:10.1080/10408398009527278.
6. Hawser, S. 1996. Adhesion of different Candida spp. to plastic: XTT formazan determinations. Med. Mycol. 34(6): 407-410. doi:10.1080/02681219680000721. PMID:8971630.
7. Kelloff, G.J., Boone, C.W., Crowell, J.A., Steele, V.E., Lubet, R., and Sigman, C.C. 1994. Chemopreventive drug development: perspectives and progress. Cancer Epidemiol. Biomark. Prev. 3(1): 85-98. PMID:8118391.
8. Kuhn, D.M., Balkis, M., Chandra, J., Mukherjee, P.K., and Ghannoum, M.A. 2003. Uses and limitations of the XTT assay in studies of Candida growth and metabolism. J. Clin. Microbiol. 41(1): 506-508. doi:10.1128/JCM.41.1.506-508.2003. PMID: 12517908.
9. Lecchi, S., Allen, K.E., Pardo, J.P., Mason, A.B., and Slayman, C.W. 2005. Conformational changes of yeast plasma membrane H+-ATPase during activation by glucose: role of threonine-912 in the carboxy-terminal tail. Biochemistry, 44(50): 16 624-16 632. doi:10.1021/bi051555f. PMID:16342953.
10. 2+. J. Biol. Chem. 276(50): 46 905-46 911. doi:10.1074/jbc. M108778200. PMID:11592968.
11. Lupetti, A., Danesi, R., Campa, M., Del Tacca, M., and Kelly, S. 2002. Molecular basis of resistance to azole antifungals. Trends Mol. Med. 8(2): 76-81. doi:10.1016/S1471-4914(02)02280-3. PMID:11815273.
12. + occlusion, and inhibition of hydrolytic activity. Br. J. Pharmacol. 145(2): 236-245. doi:10.1038/sj.bjp.0706185. PMID:15753945.
13. Mardegan de Cássia, R., Klein, M.I., Golvea, M.B., Rodrigues, J.A.O., Gonçalves, R.B., and Höfling, J.F. 2006. Biotyping and genotypic diversity among oral Candida albicans strains from caries free and caries active healthy children. Braz. J. Microbiol. 37(1): 26-32. doi:10.1590/S1517-83822006000100005.
14. Martins, C.V.B., da Silva, D.L., Neres, A.T.M., Magalhães, T.F.F., Watanabe, G.A., Modolo, L.V., et al. 2009. Curcumin as a promising antifungal of clinical interest. J. Antimicrob. Chemother. 63(2): 337-339. doi:10.1093/jac/dkn488. PMID: 19038979.
15. Masuda, T., Jitoe, A., Isobe, J., Nakatani, N., and Yonemori, S. 1993. Antioxidative and anti-inflammatory curcumin-related phenolics from rhizomes of Curcuma domestica. Phytochemistry, 32(6): 1557-1560. doi:10.1016/0031-9422(93)85179-U.
16. Meunier, F. 1989. Candidiasis. Eur. J. Clin. Microbiol. Infect. Dis. 8(5): 438-447. doi:10.1007/BF01964058. PMID:2502408.
17. Mukhopadhyay, A., Basu, N., Ghatak, N., and Gujral, P.K. 1982. Anti-inflammatory and irritant activities of curcumin analogues in rats. Agents Actions, 12(4): 508-515. doi:10.1007/ BF01965935. PMID:7180736.
18. National Committee on Clinical Laboratory Standards. 2002. Reference method for broth dilution antifungal susceptibility testing of yeasts; approved standard -second edition. NCCLS document M27-A2. National Committee on Clinical Laboratory Standards, Wayne, Penn., USA.
19. Odds, F.C., Brown, A.J.P., and Gow, N.A.R. 2003. Antifungal agents: mechanisms of action. Trends Microbiol. 11(6): 272-279. doi:10.1016/S0966-842X(03)00117-3. PMID:12823944.
20. Perez, R.P., Godwin, A.K., Handel, L.M., and Hamilton, T.C. 1993. A comparison of clonogenic, microtetrazolium and sulforhodamine B assays for determination of cisplatin cytotoxicity in human ovarian carcinoma cell lines. Eur. J. Cancer, 29(3): 395-399. doi:10.1016/0959-8049(93)90394-U.
21. Rashid, B., Manzoor, N., Amin, M., and Khan, L.A. 2004. Effect of glucose, its analogs and some amino acids on pre-steady state kinetics of ATP hydrolysis by PM-ATPase of pathogenic yeast C. albicans. Korean J. Biol. Sci. 8: 307-312.
22. Saral, R. 1991. Candida and Aspergillus infections in immunocompromised patients: an overview. Rev. Infect. Dis. 13(3): 487-492. PMID:1866554.
23. Sharma, M., Manoharlal, R., Shukla, S., Puri, N., Prasad, T., Ambudkar, S.V., and Prasad, R. 2009. Curcumin modulates efflux mediated by yeast ABC multidrug transporters and is synergistic with antifungals. J. Antimicrob. Agents Chemother. 35: 3256-3265.
24. Sharma, M., Manoharlal, R., Puri, N., and Prasad, R. 2010. Antifungal curcumin induces reactive oxygen species and triggers an early apoptosis but prevents hyphae development by targeting the global repressor TUP1 in Candida albicans. Biosci. Rep. 30(6): 391-404. doi:10.1042/BSR20090151. PMID:20017731.
25. Tsao, S.-M., and Yin, M.-C. 2000. Enhanced inhibitory effect from interaction of curcumin with amphotericin B or fluconazole against Candida species. J. Food Drug Anal. 8(3): 208-212.
26. Wu, T., Wright, K., Hurst, S.F., and Morrison, C.J. 2000. Enhanced extracellular production of aspartyl proteinase, a virulence factor, by Candida albicans isolates following growth in subinhibitory concentrations of fluconazole. Antimicrob. Agents Chemother. 44(5): 1200-1208. doi:10.1128/AAC.44.5.1200-1208.2000. PMID:10770752.