Different populations of circulating endothelial cells in patients with age-related macular degeneration: A novel insight into pathogenesis

Investigative Ophthalmology and Visual Science

Volumn 52, Issue 1, 2011, Pages 93-100

  Machalińska, Anna ^a,b   Safranow, Krzysztof ^c   Dziedziejko, Violetta ^c   Mozolewska Piotrowska, Katarzyna ^b   Paczkowska, Edyta ^d   KŁos, Patrycja ^d   Pius, Ewa ^d   GrymuŁa, Katarzyna ^d   Wiszniewska, Barbara ^a   Karczewicz, Danuta ^b   Machaliński, BogusŁaw ^d  

^a Departments of Histology and Embryology   (Poland)

^b Departments of Ophthalmology   (Poland)

^c Departments of Biochemistry and Medical Chemistry   (Poland)

^d POMERANIAN MEDICAL UNIVERSITY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

CD133 ANTIGEN; CD34 ANTIGEN; ENDOTHELIN 1; HEPATOCYTE GROWTH FACTOR 1; SCATTER FACTOR; SOMATOMEDIN C; STROMAL CELL DERIVED FACTOR 1; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN; VASCULOTROPIN; CYTOKINE; LEUKOCYTE ANTIGEN; VASCULOTROPIN A;

AGED; ARTICLE; BLOOD SAMPLING; CELL COUNT; CELL FUNCTION; CELL MIGRATION; CELL POPULATION; CIRCULATING ENDOTHELIUM CELL; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; FLUORESCENCE ANALYSIS; HUMAN; HUMAN CELL; IMMUNOCYTOFLUORESCENCE ASSAY; MALE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN CONTENT; PROTEIN EXPRESSION; RETINA MACULA AGE RELATED DEGENERATION; RETINA NEOVASCULARIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; BLOOD; CIRCULATION; FLUORESCENT ANTIBODY TECHNIQUE; HEMATOPOIETIC STEM CELL; METABOLISM; PATHOLOGY; RETINA MACULA DEGENERATION; VASCULAR ENDOTHELIUM;

AGED; ANTIGENS, CD; BLOOD CIRCULATION; BLOTTING, WESTERN; CYTOKINES; ENDOTHELIN-1; ENDOTHELIUM, VASCULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HEMATOPOIETIC STEM CELLS; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MACULAR DEGENERATION; MALE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 79952233118     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.10-5756     Document Type: Article

References (44)

1. Buch H, Vinding T, La Cour M, Appleyard M, Jensen GB, Nielsen NV. Prevalence and causes of visual impairment and blindness among 9980 Scandinavian adults: the Copenhagen City Eye Study. Ophthalmology. 2004;111:53-61.
2. Congdon N, O'Colmain B, Klaver CC, et al., Eye Diseases Prevalence Research Group. Causes and prevalence of visual impairment among adults in the United States. Arch Ophthalmol. 2004; 122:477-485.
3. Evans JR. Risk factors for age-related macular degeneration (review). Prog Retin Eye Res. 2001;20:227-253.
4. Hogg RE, Woodside JV, Gilchrist SE, et al. Cardiovascular disease and hypertension are strong risk factors for choroidal neovascu-larization. Ophthalmology. 2008;115:1046-1052.e2.
5. Haefliger IO, Flammer J, Bény JL, Lüscher TF. Endothelium-depen-dent vasoactive modulation in the ophthalmic circulation. Prog Retin Eye Res. 2001;20:209-225.
6. Lip PL, Blann AD, Hope-Ross M, Gibson JM, Lip GY. Age-related macular degeneration is associated with increased vascular endo-thelial growth factor, hemorheology and endothelial dysfunction. Ophthalmology. 2001;108:705-710.
7. Erdbruegger U, Haubitz M, Woywodt A. Circulating endothelial cells: a novel marker of endothelial damage. Clin Chim Acta. 2006;373:17-26.
8. Real C, Caiado F, Dias S. Endothelial progenitors in vascular repair and angiogenesis: how many are needed and what to do (review)? Cardiovasc Hematol Disord Drug Targets. 2008;8:185-193.
9. Tomita M, Yamada H, Adachi Y, et al. Choroidal neovascularization is provided by bone marrow cells. Stem Cells. 2004;22:21-26.
10. Espinosa-Heidmann DG, Caicedo A, Hernandez EP, Csaky KG, Cousins SW. Bone marrow-derived progenitor cells contribute to experimental choroidal neovascularization. Invest Ophthalmol Vis Sci. 2003;44:4914-4919.
11. Sengupta N, Caballero S, Mames RN, et al. Preventing stem cell incorporation into choroidal neovascularization by targeting homing and attachment factors. Invest Ophthalmol Vis Sci. 2005;46: 343-348.
12. Leone AM, Valgimigli M, Giannico MB, et al. From bone marrow to the arterial wall: the ongoing tale of endothelial progenitor cells. Eur Heart J. 2009;30:890-899.
13. Fox A, Smythe J, Fisher N, et al. Mobilization of endothelial progenitor cells into the circulation in burned patients. Br J Surg. 2008;95:244-251.
14. Smythe J, Fox A, Fisher N, et al. Measuring angiogenic cytokines, circulating endothelial cells, and endothelial progenitor cells in peripheral blood and cord blood: VEGF and CXCL12 correlate with the number of circulating endothelial progenitor cells in peripheral blood. Tissue Eng Part C Methods. 2008;14:59-67.
15. Fürstenberger G, von Moos R, Lucas R, et al. Circulating endothe-lial cells and angiogenic serum factors during neoadjuvant chemotherapy of primary breast cancer. Br J Cancer. 2006;94:524-531.
16. Félétou M, Vanhoutte PM. Endothelial dysfunction: a multifaceted disorder (The Wiggers Award Lecture). Am J Physiol Heart Circ Physiol. 2006;291:H985-H1002.
17. Boos CJ, Lip GY, Blann AD. Circulating endothelial cells in cardiovascular disease. J Am Coll Cardiol. 2006;4:1538-1547.
18. McClung JA, Naseer N, Saleem M, et al. Circulating endothelial cells are elevated in patients with type 2 diabetes mellitus independently of HbA(1)c. Diabetologia. 2005;48:345-350.
19. Clancy RM. Circulating endothelial cells and vascular injury in systemic lupus erythematosus. Curr Rheumatol Rep. 2000;2: 39-43.
20. Nadar SK, Lip GY, Lee KW, Blann AD. Circulating endothelial cells in acute ischaemic stroke. Thromb Haemost. 2005;94:707-712.
21. Beerepoot LV, Mehra N, Vermaat JS, Zonnenberg BA, Gebbink MF, Voest EE. Increased levels of viable circulating endothelial cells are an indicator of progressive disease in cancer patients. Ann Oncol. 2004;15:139-145.
22. Pang IH, Yorio T. Ocular actions of endothelins. Proc Soc Exp Biol Med. 1997;215:21-34.
23. Prasanna G, Krishnamoorthy R, Clark AF, Wordinger RJ, Yorio T. Human optic nerve head astrocytes as a target for endothelin-1. Invest Ophthalmol Vis Sci. 2002;43:2704-2713.
24. Yamagishi S, Hsu CC, Kobayashi K, Yamamoto H. Endothelin 1 mediates endothelial cell-dependent proliferation of vascular peri-cytes. Biochem Biophys Res Commun. 1993;191:840-846.
25. Torbidoni V, Iribarne M, Ogawa L, Prasanna G, Suburo AM. Endo-thelin-1 and endothelin receptors in light-induced retinal degeneration. Exp Eye Res. 2005;81:265-275.
26. Torbidoni V, Iribarne M, Suburo AM. Endothelin receptors in light-induced retinal degeneration. Exp Biol Med (Maywood). 2006;231:1095-1100.
27. Adamiec-Mroczek J, Oficjalska-Młyńczak J, Misiuk-Hojło M. Roles of endothelin-1 and selected proinflammatory cytokines in the pathogenesis of proliferative diabetic retinopathy: analysis of vitreous samples. Cytokine. 2010;49:269-274.
28. Roldán-Pallarés M, Rollín R, Mediero A, et al. Immunoreactive ET-1 in the vitreous humor and epiretinal membranes of patients with proliferative vitreoretinopathy. Mol Vis. 2005;11:461-741.
29. Shah R. Endothelins in health and disease. Eur J Intern Med. 2007;18:272-282.
30. Sengupta N, Caballero S, Mames RN, Butler JM, Scott EW, Grant MB. The role of adult bone marrow-derived stem cells in choroidal neovascularization. Invest Ophthalmol Vis Sci. 2003;44:4908-4913.
31. Yodoi Y, Sasahara M, Kameda T, Yoshimura N, Otani A. Circulating hematopoietic stem cells in patients with neovascular age-related macular degeneration. Invest Ophthalmol Vis Sci. 2007;48:5464- 5472.
32. Versari D, Daghini E, Virdis A, Ghiadoni L, Taddei S. Endothelial dysfunction as a target for prevention of cardiovascular disease. Diabetes Care. 2009;32:S314-S321.
33. Thill M, Strunnikova NV, Berna MJ, et al. Late outgrowth endothe-lial progenitor cells in patients with age-related macular degeneration. Invest Ophthalmol Vis Sci. 2008;49:2696-2708.
34. Smith LE, Shen W, Perruzzi C, et al. Regulation of vascular endo-thelial growth factor-dependent retinal neovascularization by insulin-like growth factor-1 receptor. Nat Med. 1999;5:1390-1395.
35. Dills DG, Moss SE, Klein R, Klein BE. Association of elevated IGF-I levels with increased retinopathy in late-onset diabetes. Diabetes. 1991;40:1725-1730.
36. Grant M, Russell B, Fitzgerald C, Merimee TJ. Insulin-like growth factors in vitreous: studies in control and diabetic subjects with neovascularization. Diabetes. 1986;35:416-420.
37. Hellstrom A, Perruzzi C, Ju M, et al. Low IGF-I suppresses VEGF-survival signaling in retinal endothelial cells: direct correlation with clinical retinopathy of prematurity. Proc Natl Acad Sci U S A. 2001;98:5804-5808.
38. Bhutto IA, McLeod DS, Merges C, Hasegawa T, Lutty GA. Localisation of SDF-1and its receptor CXCR4 in retina and choroid of aged human eyes and in eyes with age related macular degeneration. Br J Ophthalmol. 2006;90:906-910.
39. van Weel V, Seghers L, de Vries MR, et al. Expression of vascular endothelial growth factor, stromal cell-derived factor-1, and CXCR4 in human limb muscle with acute and chronic ischemia. Arterioscler Thromb Vasc Biol. 2007;27:1426-1432.
40. Xiao Q, Kiechl S, Patel S, et al. Endothelial progenitor cells, cardiovascular risk factors, cytokine levels and atherosclerosis: results from a large population-based study. PLoS One. 2007;2:e975.
41. Xiao Q, Ye S, Oberhollenzer F, et al. SDF1 gene variation is associated with circulating SDF1alpha level and endothelial progenitor cell number: the Bruneck Study. PLoS One. 2008;3:e4061.
42. Yamaguchi J, Kusano KF, Masuo O, et al. Stromal cell-derived factor-1 effects on ex vivo expanded endothelial progenitor cell recruitment for ischemic neovascularization. Circulation. 2003; 107:1322-1328.
43. Zheng H, Fu G, Dai T, Huang H. Migration of endothelial progenitor cells mediated by stromal cell-derived factor-1alpha/CXCR4 via PI3K/Akt/eNOS signal transduction pathway. J Cardiovasc Pharmacol. 2007;50:274-280.
44. De Falco E, Porcelli D, Torella AR, et al. SDF-1 involvement in endothelial phenotype and ischemia-induced recruitment of bone marrow progenitor cells. Blood. 2004;104:3472-3482.