Liquid chromatography tandem mass spectrometry method for determination of N-acetylcysteine in human plasma using an isotope-labeled internal standard

Biomedical Chromatography

Volumn 25, Issue 4, 2011, Pages 427-431

  Lu, Chuan ^a   Liu, Gangyi ^a   Jia, Jingying ^a   Gui, Yuzhou ^b   Liu, Yanmei ^a   Zhang, Mengqi ^a   Liu, Yun ^a   Li, Shuijun ^a   Yu, Chen ^a  

^a SHANGHAI XUHUI CENTRAL HOSPITAL   (China)

^b Shanghai Clinical Research Center   (China)

Author keywords

Bioequivalence; Human plasma; LC MS MS; N acetylcysteine

Indexed keywords

ELECTROSPRAY IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PLASMA (HUMAN); TRICHLOROACETIC ACID;

BIOEQUIVALENCE; HUMAN PLASMAS; LABELED INTERNAL STANDARDS; LC-MS-MS; LC.MS/MS; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRY; MASS SPECTROMETRIC DETECTION; N-ACETYLCYSTEINE; POSITIVE ELECTROSPRAY IONIZATION;

ISOTOPES;

ACETYLCYSTEINE; DEUTERIUM; ISOTOPE; TRICHLOROACETIC ACID;

ARTICLE; BIOEQUIVALENCE; DRUG BLOOD LEVEL; ELECTROSPRAY; EXTRACTION; HUMAN; HUMAN EXPERIMENT; ISOTOPE LABELING; LIQUID CHROMATOGRAPHY; NORMAL HUMAN; PLASMA; SENSITIVITY AND SPECIFICITY; STANDARD; TANDEM MASS SPECTROMETRY;

EID: 79952230551     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1465     Document Type: Article

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