Reproduction among 1975 Sardinian women and men diagnosed with major mood disorders

Acta Psychiatrica Scandinavica

Volumn 123, Issue 4, 2011, Pages 283-289

  Tondo, L ^a,b   Lepri, B ^b   Baldessarini, R J ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Lucio Bini Mood Disorder Center   (Italy)

Author keywords

Bipolar; Children; Depression; Fertility; Marriage; Mood disorders; Reproduction

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; BIPOLAR I DISORDER; BIPOLAR II DISORDER; CONTROLLED STUDY; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; EDUCATIONAL STATUS; ELECTRONIC MEDICAL RECORD; EVALUATION AND FOLLOW UP; FEMALE; FERTILITY; HUMAN; MAJOR AFFECTIVE DISORDER; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MARRIAGE; ONSET AGE; PRIORITY JOURNAL; REPRODUCTION;

ADULT; AGE OF ONSET; BIPOLAR DISORDER; BIRTH RATE; DEPRESSIVE DISORDER, MAJOR; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; FAMILY CHARACTERISTICS; FEMALE; FERTILITY; HUMANS; INTERVIEW, PSYCHOLOGICAL; ITALY; MALE; REPRODUCTIVE BEHAVIOR; SEX FACTORS; SEXUALITY;

EID: 79952228928     PISSN: 0001690X     EISSN: 16000447     Source Type: Journal    
DOI: 10.1111/j.1600-0447.2010.01660.x     Document Type: Article

References (18)

1. Odergard O. Fertility of psychiatric first admissions in Norway 1936-1975. Acta Psychiatr Scand 1980;62:212-220.
2. Baron M, Risch N, Mendlewicz J. Differential fertility in bipolar affective illness. J Affect Disord 1982;4:103-112.
3. Calzeroni A, Conte G, Pennati A, Vita A, Sacchetti E. Celibacy and fertility rates in patients with major affective disorders: relevance of delusional symptoms and suicidal behavior. Acta Psychiatr Scand 1990;82:3009-3010.
4. Jonsson SA. Marriage rate and fertility in cyclic psychosis: comparison with affective disorder, schizophrenia, and the general population. Eur Arch Psychiatry Clin Neurosci 1991;24:119-125.
5. Williams KE, Marsh WK, Rasgon NL. Mood disorders and fertility in women: critical review of the literature and implications for future research. Hum Reprod Update 2007;13:607-616.
6. Kallmann FJ. Heredity in health and mental disorder. New York: WW Norton, 1953.
7. Hopkinson G. Celibacy and marital fertility in manic-depressive patients. Acta Psychiatr Scand 1963;39:473-476.
8. Perris C. Study of bipolar (manic-depressive) and unipolar recurrent depressive psychoses: celibacy rate and fertility. Acta Psychiatr Scand 1966;41(Suppl 194):58-67.
9. Tondo L, Lepri B, Baldessarini RJ. Risks of suicidal ideation, attempts and suicides among 2826 men and women with types I and II bipolar, and recurrent major depressive disorders. Acta Psychiatr Scand 2007;116:419-428.
10. Tondo L, LEPRI B, CRUZ N, Baldessarini RJ. Age at onset in 3014 Sardinian bipolar and major depressive disorder patients. Acta Psychiatr Scand 2010;121:446-452.
11. Bernardi L, Oppo A Fertility and family configurations in Sardinia. MPIDR Working Paper WP-2007-033. Rostock, Germany: Max-Planck Institute for Demographic Research, 2007, 25 pp.
12. NationMaster.com. Fertility rates by country. Accessible at: (accessed February 12, 2010).
13. ISTAT (Italian National Institute of Statistics). Accessible at: (accessed June 14, 2010).
14. Mondimore FM, Zandi PP, Mackinnon DF et al. Familial aggregation of illness chronicity in recurrent, early-onset major depression pedigrees. Am J Psychiatry 2006;163:1554-1560.
15. Post RM, Leverich GS, Kupka RW et al. Early-onset bipolar disorder and treatment delay are risk factors for poor outcome in adulthood. J Clin Psychiatry 2010;71:864-872.
16. Hopflinger F. Cohort fertility in Western Europe: comparing fertility trends in recent birth cohorts. Genus 1984;40:19-46.
17. McCauley AP, Robey B, Blanc AK, Geller JS. Opportunities for women through reproductive choice. Popul Rep M 1994;12:1-39.
18. Shah I. Fertility and contraception in Europe: the case of low fertility in southern Europe. Eur J Contracept Reprod Health Care 1997;2:53-61.