-
1
-
-
0036661219
-
Pancreatic cancer
-
Yeo TP, Hruban RH, Leach SD, Wilentz RE, Sohn TA, Kern SE, Iacobuzio-Donahue CA, Maitra A, Goggins M, Canto MI, Abrams RA, Laheru D, Jaffee EM, Hidalgo M and Yeo CJ: Pancreatic cancer. Curr Probl Cancer 26: 176-275, 2002.
-
(2002)
Curr Probl Cancer
, vol.26
, pp. 176-275
-
-
Yeo, T.P.1
Hruban, R.H.2
Leach, S.D.3
Wilentz, R.E.4
Sohn, T.A.5
Kern, S.E.6
Iacobuzio-Donahue, C.A.7
Maitra, A.8
Goggins, M.9
Canto, M.I.10
Abrams, R.A.11
Laheru, D.12
Jaffee, E.M.13
Hidalgo, M.14
Yeo, C.J.15
-
2
-
-
1642588228
-
Pancreatic cancer
-
DOI 10.1016/S0140-6736(04)15841-8, PII S0140673604158418
-
Li D, Xie K, Wolff R and Abbruzzese JL: Pancreatic cancer. Lancet 363: 1049-1057, 2004. (Pubitemid 38410779)
-
(2004)
Lancet
, vol.363
, Issue.9414
, pp. 1049-1057
-
-
Li, D.1
Xie, K.2
Wolff, R.3
Abbruzzese, J.L.4
-
3
-
-
1542285510
-
Involvement of p38 mitogen-activated protein kinase in gemcitabine-induced apoptosis in human pancreatic cancer cells
-
DOI 10.1016/j.bbrc.2004.02.017, PII S0006291X04002621
-
Habiro A, Tanno S, Koizumi K, Izawa T, Nakano Y, Osanai M, Mizukami Y, Okumura T and Kohgo Y: Involvement of p38 mitogen-activated protein kinase in gemcitabine-induced apoptosis in human pancreatic cancer cells. Biochem Biophys Res Commun 316: 71-77, 2004. (Pubitemid 38299130)
-
(2004)
Biochemical and Biophysical Research Communications
, vol.316
, Issue.1
, pp. 71-77
-
-
Habiro, A.1
Tanno, S.2
Koizumi, K.3
Izawa, T.4
Nakano, Y.5
Osanai, M.6
Mizukami, Y.7
Okumura, T.8
Kohgo, Y.9
-
4
-
-
0033559213
-
An investigational new drug treatment program for patients with gemcitabine: Results for over 3000 patients with pancreatic carcinoma
-
DOI 10.1002/(SICI)1097-0142(19990315)85:6<1261::AID-CNCR7>3.0.CO;2- T
-
Storniolo AM, Enas NH, Brown CA, Voi M, Rothenberg ML and Schilsky R: An investigational new drug treatment program for patients with gemcitabine: results for over 3000 patients with pancreatic carcinoma. Cancer 85: 1261-1268, 1999. (Pubitemid 29125078)
-
(1999)
Cancer
, vol.85
, Issue.6
, pp. 1261-1268
-
-
Storniolo, A.M.1
Enas, N.H.2
Brown, C.A.3
Voi, M.4
Rothenberg, M.L.5
Schilsky, R.6
-
5
-
-
0036462584
-
Determinants of resistance to 2′,2′-difluorodeoxycytidine (gemcitabine)
-
Bergman AM, Pinedo HM and Peters GJ: Determinants of resistance to 2′,2′-difluorodeoxycytidine (gemcitabine). Drug Resist Updat 5: 19-33, 2002.
-
(2002)
Drug Resist Updat
, vol.5
, pp. 19-33
-
-
Bergman, A.M.1
Pinedo, H.M.2
Peters, G.J.3
-
6
-
-
0036078423
-
Cytotoxic activity of 2′,2′-difluorodeoxycytidine, 5-aza-2′-deoxycytidine and cytosine arabinoside in cells transduced with deoxycytidine kinase gene
-
DOI 10.1016/S0006-291X(02)00413-8, PII S0006291X02004138
-
Beausejour CM, Gagnon J, Primeau M and Momparler RL: Cytotoxic activity of 2′,2′-difluorodeoxycytidine, 5-aza-2′- deoxycytidine and cytosine arabinoside in cells transduced with deoxycytidine kinase gene. Biochem Biophys Res Commun 293: 1478-1484, 2002. (Pubitemid 34681044)
-
(2002)
Biochemical and Biophysical Research Communications
, vol.293
, Issue.5
, pp. 1478-1484
-
-
Beausejour, C.M.1
Gagnon, J.2
Primeau, M.3
Momparler, R.L.4
-
7
-
-
2642535305
-
Resistance to gemcitabine in a human follicular lymphoma cell line is due to partial deletion of the deoxycytidine kinase gene
-
Galmarini CM, Clarke ML, Jordheim L, Santos CL, Cros E, Mackey JR and Dumontet C: Resistance to gemcitabine in a human follicular lymphoma cell line is due to partial deletion of the deoxycytidine kinase gene. BMC Pharmacol 4: 8, 2004.
-
(2004)
BMC Pharmacol
, vol.4
, pp. 8
-
-
Galmarini, C.M.1
Clarke, M.L.2
Jordheim, L.3
Santos, C.L.4
Cros, E.5
Mackey, J.R.6
Dumontet, C.7
-
8
-
-
0033800910
-
Cross-resistance in the 2′,2′-difluorodeoxycytidine (gemcitabine)-resistant human ovarian cancer cell line AG6000 to standard and investigational drugs
-
Bergman AM, Giaccone G, van Moorsel CJ, Mauritz R, Noordhuis P, Pinedo HM and Peters GJ: Cross-resistance in the 2′,2′-difluorodeoxycytidine (gemcitabine)-resistant human ovarian cancer cell line AG6000 to standard and investigational drugs. Eur J Cancer 36: 1974-1983, 2000.
-
(2000)
Eur J Cancer
, vol.36
, pp. 1974-1983
-
-
Bergman, A.M.1
Giaccone, G.2
Van Moorsel, C.J.3
Mauritz, R.4
Noordhuis, P.5
Pinedo, H.M.6
Peters, G.J.7
-
9
-
-
49049100257
-
Down-regulation of deoxycytidine kinase enhances acquired resistance to gemcitabine in pancreatic cancer
-
Ohhashi S, Ohuchida K, Mizumoto K, Fujita H, Egami T, Yu J, Toma H, Sadatomi S, Nagai E and Tanaka M: Down-regulation of deoxycytidine kinase enhances acquired resistance to gemcitabine in pancreatic cancer. Anticancer Res 28: 2205-2212, 2008.
-
(2008)
Anticancer Res
, vol.28
, pp. 2205-2212
-
-
Ohhashi, S.1
Ohuchida, K.2
Mizumoto, K.3
Fujita, H.4
Egami, T.5
Yu, J.6
Toma, H.7
Sadatomi, S.8
Nagai, E.9
Tanaka, M.10
-
10
-
-
33646407273
-
Immunohistochemical and genetic evaluation of deoxycytidine kinase in pancreatic cancer: Relationship to molecular mechanisms of gemcitabine resistance and survival
-
Sebastiani V, Ricci F, Rubio-Viqueira B, Kulesza P, Yeo CJ, Hidalgo M, Klein A, Laheru D and Iacobuzio-Donahue CA: Immunohistochemical and genetic evaluation of deoxycytidine kinase in pancreatic cancer: relationship to molecular mechanisms of gemcitabine resistance and survival. Clin Cancer Res 12: 2492-2497, 2006.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2492-2497
-
-
Sebastiani, V.1
Ricci, F.2
Rubio-Viqueira, B.3
Kulesza, P.4
Yeo, C.J.5
Hidalgo, M.6
Klein, A.7
Laheru, D.8
Iacobuzio-Donahue, C.A.9
-
11
-
-
0029924620
-
Viral vector transduction of the human deoxycytidine kinase cDNA sensitizes glioma cells to the cytotoxic effects of cytosine arabinoside in vitro and in vivo
-
DOI 10.1038/nm0596-567
-
Manome Y, Wen PY, Dong Y, Tanaka T, Mitchell BS, Kufe DW and Fine HA: Viral vector transduction of the human deoxycytidine kinase cDNA sensitizes glioma cells to the cytotoxic effects of cytosine arabinoside in vitro and in vivo. Nat Med 2: 567-573, 1996. (Pubitemid 26150684)
-
(1996)
Nature Medicine
, vol.2
, Issue.5
, pp. 567-573
-
-
Manome, Y.1
Wen, P.Y.2
Dong, Y.3
Tanaka, T.4
Mitchell, B.S.5
Kufe, D.W.6
Fine, H.A.7
-
12
-
-
0034470702
-
The role of deoxycytidine kinase in gemcitabine cytotoxicity
-
Van der Wilt CL, Kroep JR, Bergman AM, Loves WJ, Alvarez E, Talianidis I, Eriksson S, van Groeningen CJ, Pinedo HM and Peters GJ: The role of deoxycytidine kinase in gemcitabine cytotoxicity. Adv Exp Med Biol 486: 287-290, 2000. (Pubitemid 32179314)
-
(2000)
Advances in Experimental Medicine and Biology
, vol.486
, pp. 287-290
-
-
Van, D.W.C.L.1
Kroep, J.R.2
Bergman, A.M.3
Loves, W.J.P.4
Alvarez, E.5
Talianidis, I.6
Eriksson, S.7
Van, G.C.J.8
Pinedo, H.M.9
Peters, G.J.10
-
13
-
-
0035119539
-
Expression of p8 in human pancreatic cancer
-
Su SB, Motoo Y, Iovanna JL, Xie MJ, Mouri H, Ohtsubo K, Yamaguchi Y, Watanabe H, Okai T, Matsubara F and Sawabu N: Expression of p8 in human pancreatic cancer. Clin Cancer Res 7: 309-313, 2001. (Pubitemid 32184317)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.2
, pp. 309-313
-
-
Su, S.-B.1
Motoo, Y.2
Iovanna, J.L.3
Xie, M.-J.4
Mouri, H.5
Ohtsubo, K.6
Yamaguchi, Y.7
Watanabe, H.8
Okai, T.9
Matsubara, F.10
Sawabu, N.11
-
14
-
-
31544450585
-
p8 is a new target of gemcitabine in pancreatic cancer cells
-
DOI 10.1158/1078-0432.CCR-05-1700
-
Giroux V, Malicet C, Barthet M, Gironella M, Archange C, Dagorn JC, Vasseur S and Iovanna JL: p8 is a new target of gemcitabine in pancreatic cancer cells. Clin Cancer Res 12: 235-241, 2006. (Pubitemid 43166199)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.1
, pp. 235-241
-
-
Giroux, V.1
Malicet, C.2
Barthet, M.3
Gironella, M.4
Archange, C.5
Dagorn, J.-C.6
Vasseur, S.7
Iovanna, J.L.8
-
15
-
-
0034895893
-
Overexpression of p8 is inversely correlated with apoptosis in pancreatic cancer
-
Su SB, Motoo Y, Iovanna JL, Berthezene P, Xie MJ, Mouri H, Ohtsubo K, Matsubara F and Sawabu N: Overexpression of p8 is inversely correlated with apoptosis in pancreatic cancer. Clin Cancer Res 7: 1320-1324, 2001. (Pubitemid 32708687)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.5
, pp. 1320-1324
-
-
Su, S.-B.1
Motoo, Y.2
Iovanna, J.L.3
Berthezene, P.4
Xie, M.-J.5
Mouri, H.6
Ohtsubo, K.7
Matsubara, F.8
Sawabu, N.9
-
16
-
-
21244502175
-
Possible antitumor activity of 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl) cytosine (ECyd, TAS-106) against an established gemcitabine (dFdCyd)-resistant human pancreatic cancer cell line
-
DOI 10.1111/j.1349-7006.2005.00046.x
-
Kazuno H, Sakamoto K, Fujioka A, Fukushima M, Matsuda A and Sasaki T: Possible antitumor activity of 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl) cytosine (ECyd, TAS-106) against an established gemcitabine (dFdCyd)-resistant human pancreatic cancer cell line. Cancer Sci 96: 295-302, 2005. (Pubitemid 40895078)
-
(2005)
Cancer Science
, vol.96
, Issue.5
, pp. 295-302
-
-
Kazuno, H.1
Sakamoto, K.2
Fujioka, A.3
Fukushima, M.4
Matsuda, A.5
Sasaki, T.6
-
17
-
-
0037082484
-
Functional role of alternatively spliced deoxycytidine kinase in sensitivity to cytarabine of acute myeloid leukemic cells
-
DOI 10.1182/blood.V99.4.1373
-
Veuger MJ, Heemskerk MH, Honders MW, Willemze R and Barge RM: Functional role of alternatively spliced deoxycytidine kinase in sensitivity to cytarabine of acute myeloid leukemic cells. Blood 99: 1373-1380, 2002. (Pubitemid 34547094)
-
(2002)
Blood
, vol.99
, Issue.4
, pp. 1373-1380
-
-
Veuger, M.J.T.1
Heemskerk, M.H.M.2
Willy, H.M.3
Willemze, R.4
Barge, R.M.Y.5
-
18
-
-
34248679167
-
Tricine-SDS-PAGE
-
Schagger H: Tricine-SDS-PAGE. Nat Protoc 1: 16-22, 2006.
-
(2006)
Nat Protoc
, vol.1
, pp. 16-22
-
-
Schagger, H.1
-
19
-
-
53149121678
-
Eplin-alpha expression in human breast cancer, the impact on cellular migration and clinical outcome
-
Jiang WG, Martin TA, Lewis-Russell JM, Douglas-Jones A, Ye L and Mansel RE: Eplin-alpha expression in human breast cancer, the impact on cellular migration and clinical outcome. Mol Cancer 7: 71, 2008.
-
(2008)
Mol Cancer
, vol.7
, pp. 71
-
-
Jiang, W.G.1
Martin, T.A.2
Lewis-Russell, J.M.3
Douglas-Jones, A.4
Ye, L.5
Mansel, R.E.6
-
20
-
-
0347594125
-
Prognostic Value of Rho GTPases and Rho Guanine Nucleotide Dissociation Inhibitors in Human Breast Cancers
-
Jiang WG, Watkins G, Lane J, Cunnick GH, Douglas-Jones A, Mokbel K and Mansel RE: Prognostic value of rho GTPases and rho guanine nucleotide dissociation inhibitors in human breast cancers. Clin Cancer Res 9: 6432-6440, 2003. (Pubitemid 38031830)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.17
, pp. 6432-6440
-
-
Jiang, W.G.1
Watkins, G.2
Lane, J.3
Cunnick, G.H.4
Douglas-Jones, A.5
Mokbel, K.6
Mansel, R.E.7
-
21
-
-
34249092004
-
Synergistic effect of triptolide combined with 5-fluorouracil on colon carcinoma
-
DOI 10.1136/pgmj.2006.055426
-
Tang XY, Zhu YQ, Tao WH, Wei B and Lin XL: Synergistic effect of triptolide combined with 5-fluorouracil on colon carcinoma. Postgrad Med J 83: 338-343, 2007. (Pubitemid 46797833)
-
(2007)
Postgraduate Medical Journal
, vol.83
, Issue.979
, pp. 338-343
-
-
Tang, X.-Y.1
Zhu, Y.-Q.2
Tao, W.-H.3
Wei, B.4
Lin, X.-L.5
-
22
-
-
73449129412
-
GalNAc-T14 may be involved in regulating the apoptotic action of IGFBP-3
-
Wu C, Shan Y, Liu X, Song W, Wang J, Zou M, Wang M and Xu D: GalNAc-T14 may be involved in regulating the apoptotic action of IGFBP-3. J Biosci 34: 389-395, 2009.
-
(2009)
J Biosci
, vol.34
, pp. 389-395
-
-
Wu, C.1
Shan, Y.2
Liu, X.3
Song, W.4
Wang, J.5
Zou, M.6
Wang, M.7
Xu, D.8
-
23
-
-
40949087142
-
HMGA1 is a molecular determinant of chemoresistance to gemcitabine in pancreatic adenocarcinoma
-
Liau SS and Whang E: HMGA1 is a molecular determinant of chemoresistance to gemcitabine in pancreatic adenocarcinoma. Clin Cancer Res 14: 1470-1477, 2008.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 1470-1477
-
-
Liau, S.S.1
Whang, E.2
-
24
-
-
33645731188
-
Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine
-
Giovannetti E, Del TM, Mey V, Funel N, Nannizzi S, Ricci S, Orlandini C, Boggi U, Campani D, Del CM, Iannopollo M, Bevilacqua G, Mosca F and Danesi R: Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine. Cancer Res 66: 3928-3935, 2006.
-
(2006)
Cancer Res
, vol.66
, pp. 3928-3935
-
-
Giovannetti, E.1
Del, T.M.2
Mey, V.3
Funel, N.4
Nannizzi, S.5
Ricci, S.6
Orlandini, C.7
Boggi, U.8
Campani, D.9
Del, C.M.10
Iannopollo, M.11
Bevilacqua, G.12
Mosca, F.13
Danesi, R.14
-
25
-
-
33846816556
-
Gemcitabine chemoresistance and molecular markers associated with gemcitabine transport and metabolism in human pancreatic cancer cells
-
DOI 10.1038/sj.bjc.6603559, PII 6603559
-
Nakano Y, Tanno S, Koizumi K, Nishikawa T, Nakamura K, Minoguchi M, Izawa T, Mizukami Y, Okumura T and Kohgo Y: Gemcitabine chemoresistance and molecular markers associated with gemcitabine transport and metabolism in human pancreatic cancer cells. Br J Cancer 96: 457-463, 2007. (Pubitemid 46215217)
-
(2007)
British Journal of Cancer
, vol.96
, Issue.3
, pp. 457-463
-
-
Nakano, Y.1
Tanno, S.2
Koizumi, K.3
Nishikawa, T.4
Nakamura, K.5
Minoguchi, M.6
Izawa, T.7
Mizukami, Y.8
Okumura, T.9
Kohgo, Y.10
-
26
-
-
33750690650
-
Silencing of X-linked inhibitor of apoptosis (XIAP) decreases gemcitabine resistance of pancreatic cancer cells
-
Shrikhande SV, Kleeff J, Kayed H, Keleg S, Reiser C, Giese T, Buchler MW, Esposito I and Friess H: Silencing of X-linked inhibitor of apoptosis (XIAP) decreases gemcitabine resistance of pancreatic cancer cells. Anticancer Res 26: 3265-3273, 2006. (Pubitemid 44701495)
-
(2006)
Anticancer Research
, vol.26
, Issue.5 A
, pp. 3265-3273
-
-
Shrikhande, S.V.1
Kleeff, J.2
Kayed, H.3
Keleg, S.4
Reiser, C.5
Giese, T.6
Buchler, M.W.7
Esposito, I.8
Friess, H.9
-
27
-
-
4644316230
-
Proteasome inhibition sensitizes non-small-cell lung cancer to gemcitabine-induced apoptosis
-
DOI 10.1016/j.athoracsur.2004.04.029, PII S0003497504008422
-
Denlinger CE, Rundall BK, Keller MD and Jones DR: Proteasome inhibition sensitizes non-small cell lung cancer to gemcitabine-induced apoptosis. Ann Thorac Surg 78: 1207-1214, 2004. (Pubitemid 39303836)
-
(2004)
Annals of Thoracic Surgery
, vol.78
, Issue.4
, pp. 1207-1214
-
-
Denlinger, C.E.1
Rundall, B.K.2
Keller, M.D.3
Jones, D.R.4
-
28
-
-
0031465799
-
Cloning and expression of the rat p8 cDNA, a new gene activated in pancreas during the acute phase of pancreatitis, pancreatic development, and regeneration, and which promotes cellular growth
-
DOI 10.1074/jbc.272.51.32360
-
Mallo GV, Fiedler F, Calvo EL, Ortiz EM, Vasseur S, Keim V, Morisset J and Iovanna JL: Cloning and expression of the rat p8 cDNA, a new gene activated in pancreas during the acute phase of pancreatitis, pancreatic development, and regeneration, and which promotes cellular growth. J Biol Chem 272: 32360-32369, 1997. (Pubitemid 28011918)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.51
, pp. 32360-32369
-
-
Mallo, G.V.1
Fiedler, F.2
Calvo, E.L.3
Ortiz, E.M.4
Vasseur, S.5
Keim, V.6
Morisset, J.7
Iovanna, J.L.8
-
29
-
-
0033083865
-
Cloning and expression of the human p8, a nuclear protein with mitogenic activity
-
DOI 10.1046/j.1432-1327.1999.00092.x
-
Vasseur S, Vidal MG, Fiedler F, Bodeker H, Canepa E, Moreno S and Iovanna JL: Cloning and expression of the human p8, a nuclear protein with mitogenic activity. Eur J Biochem 259: 670-675, 1999. (Pubitemid 29075493)
-
(1999)
European Journal of Biochemistry
, vol.259
, Issue.3
, pp. 670-675
-
-
Vasseur, S.1
Mallo, G.V.2
Fiedler, F.3
Bodeker, H.4
Canepa, E.5
Moreno, S.6
Iovanna, J.L.7
|