Does lactate-guided therapy really improve outcome?

American Journal of Respiratory and Critical Care Medicine

Volumn 183, Issue 5, 2011, Pages 680-

  De Ruiter, Joke ^a   Zijlstra, Jan G ^a   Ligtenberg, Jack J ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

INOTROPIC AGENT; LACTIC ACID; VASODILATOR AGENT; BIOLOGICAL MARKER; ANALGESIC AGENT; DOBUTAMINE; GLYCERYL TRINITRATE; HYPERTENSIVE AGENT; SEDATIVE AGENT;

FLUID THERAPY; HUMAN; INTENSIVE CARE; INTENSIVE CARE UNIT; LENGTH OF STAY; LETTER; MORTALITY; PRIORITY JOURNAL; RISK FACTOR; TREATMENT OUTCOME; AGED; BLOOD; CRITICAL ILLNESS; METHODOLOGY; MONITORING; NOTE; ARTIFICIAL VENTILATION; BLOOD TRANSFUSION; CRITICALLY ILL PATIENT; MICROCIRCULATION; MORBIDITY; OUTCOME ASSESSMENT; OXYGEN SATURATION; OXYGEN THERAPY;

AGED, 80 AND OVER; BIOLOGICAL MARKERS; CRITICAL ILLNESS; HOSPITAL MORTALITY; HUMANS; INTENSIVE CARE; LACTIC ACID; LENGTH OF STAY; MONITORING, PHYSIOLOGIC; TREATMENT OUTCOME;

EID: 79952209414     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/ajrccm.183.5.680     Document Type: Letter

References (3)

1. Jansen TC, van Bommel J, Schoonderbeek FJ, Sleeswijk Visser SJ, van der Klooster JM, Lima AP, Willemsen SP, Bakker J; LACTATE study group. Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial. Am J Respir Crit Care Med 2010;182:752-761.
2. Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M; Early Goal-Directed Therapy Collaborative Group. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001;345:1368-1377.
3. Zijlstra J, Monteban W, Meertens J, Tulleken J, Ligtenberg J. Septic shock therapy: the recipe or the cook? Crit Care Med 2006;34:2870-2871.