The perspectives of clinical staff and bereaved informal care-givers on the use of continuous sedation until death for cancer patients: The study protocol of the UNBIASED study

BMC Palliative Care

Volumn 10, Issue , 2011, Pages

  Seymour, Jane ^a   Rietjens, Judith ^b,c   Brown, Jayne ^a   Van Der Heide, Agnes ^c   Sterckx, Sigrid ^b   Deliens, Luc ^b  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b GHENT UNIVERSITY   (Belgium)

^c ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BENZODIAZEPINE DERIVATIVE; PROPOFOL;

ADULT; ARTICLE; CANCER PATIENT; CAREGIVER; CLINICAL DECISION MAKING; CONTINUOUS INFUSION; DEATH; DRUG FATALITY; HOME CARE; HOSPITAL CARE; HUMAN; MEDICAL STAFF; NEOPLASM; NURSE; PALLIATIVE THERAPY; PHYSICIAN; SEDATION;

EID: 79952201818     PISSN: None     EISSN: 1472684X     Source Type: Journal    
DOI: 10.1186/1472-684X-10-5     Document Type: Article

References (42)

1. When cancer symptoms cannot be controlled: the role of palliative sedation. JGJ Hasselaar SCAHHVM Verhagen KCP Vissers, Current Opinion in Supportive & Palliative Care 2009 3 1 14 23
2. Sedation for terminally ill patients with cancer with uncontrollable physical distress. H Kohara H Ueoka H Takeyama T Murakami T Morita, J Palliat Med 2005 8 1 20 25 10.1089/jpm.2005.8.20 15662170 (Pubitemid 40144248)
3. Continuous deep sedation in home palliative care units: case studies in the Florence area in 2000 and in 2003-2004. F Bulli G Miccinesi E Biancalani M Fallai M Mannocci E Paci M Piazza C Tempestini P Morino, Minerva Anestesiologica 2007 73 5 291 298 17242653 (Pubitemid 47034259)
4. Palliative sedation therapy does not hasten death: results from a prospective multicenter study. M Maltoni C Pittureri E Scarpi L Piccinini F Martini P Turci L Montanari O Nanni D Amadori, Annals of Oncology 2009 20 7 1163 1169 10.1093/annonc/mdp048 19542532
5. A multicentre international study of sedation for uncontrolled symptoms in terminally ill patients. RL Fainsinger A Waller M Bercovici K Bengtson W Landman M Hosking JM Nunez-Olarte D deMoissac, Palliative Medicine 2000 14 4 257 265 10.1191/026921600666097479 10974977 (Pubitemid 30609544)
6. Palliative Sedation. J Eichenclas, Current Opinion in Supportive Palliative Care 2007 1 207 212 10.1097/SPC.0b013e3282f19f87
7. Continuous deep sedation in medical practice: a descriptive study. C Seale, Journal of Pain & Symptom Management 39 1 44 53
8. Continuous deep sedation: physicians' experiences in six European countries. G Miccinesi JAC Rietjens L Deliens E Paci G Bosshard T Nilstun M Norup G van der Wal E Consortium, Journal of Pain & Symptom Management 2006 31 2 122 129 (Pubitemid 43243665)
9. Continuous deep sedation for patients nearing death in the Netherlands: descriptive study. J Rietjens J van Delden B Onwuteaka-Philipsen H Buiting P van der Maas A van der Heide, BMJ 2008 336 7648 810 813 10.1136/bmj.39504.531505.25 18344245 (Pubitemid 351548222)
10. European Association for Palliative Care (EAPC) recommended framework for the use of sedation in palliative care. NI Cherny L Radbruch Board of the European Association for Palliative C, Palliative Medicine 2009 23 7 581 593 10.1177/0269216309107024 19858355
11. Palliative treatments of last resort: choosing the least harmful alternative. University of Pennsylvania Center for Bioethics Assisted Suicide Consensus Panel. TE Quill BC Lee S Nunn, Annals of Internal Medicine 2000 132 6 488 493 10733450
12. Last-resort options for palliative sedation. TE Quill B Lo DW Brock A Meisel, Annals of Internal Medicine 2009 151 6 421 424 19755367
13. The use of opioids and sedatives at the end of life. N Sykes A Thorns, Lancet Oncology 2003 4 5 312 318 10.1016/S1470-2045(03)01079-9 12732169 (Pubitemid 36592499)
14. Palliative sedation in a specialized unit for acute palliative care in a cancer hospital: comparing patients dying with and without palliative sedation. JAC Rietjens L van Zuylen H van Veluw L van der Wijk A van der Heide CCD van der Rijt, Journal of Pain & Symptom Management 2008 36 3 228 234
15. Physician reports of terminal sedation without hydration or nutrition for patients nearing death in the Netherlands. JA Rietjens A van der Heide AM Vrakking BD Onwuteaka-Philipsen PJ van der Maas G van der Wal, Ann Intern Med 2004 141 3 178 185 15289214
16. Continuous Deep Sedation Until Death in Belgium: A Nationwide Survey. K Chambaere J Bilsen J Cohen JA Rietjens BD Onwuteaka-Philipsen F Mortier L Deliens, Archives of Internal Medicine 2010 170 5 490 493 10.1001/archinternmed. 2009.542 20212190
17. Terminal Sedation: Pulling the Sheet over Our Eyes. MP Battin, Hastings Center Report 2008 38 5 27 30 10.1353/hcr.0.0057 18947136
18. European Association for Palliative Care (EAPC) framework for palliative sedation: an ethical discussion. N Juth A Lindblad N Lynoe M Sjostrand G Helgesson, BMC Palliat Care 2010 9 20 10.1186/1472-684X-9-20 20836861
19. Continuous deep sedation at the end of life and the 'natural death' hypothesis. K Raus S Sterckx F Mortier, Bioethics 2011 21241346
20. National Hospice and Palliative Care Organization (NHPCO) Position Statement and Commentary on the Use of Palliative Sedation in Imminently Dying Terminally Ill Patients. TW Kirk MM Mahon, Journal of Pain and Symptom Management 2010 39 5 914 923 10.1016/j.jpainsymman.2010.01.009 20471551
21. Palliative sedation therapy in the last weeks of life: a literature review and recommendations for standards. A de Graeff M Dean, J Palliat Med 2007 10 1 67 85 10.1089/jpm.2006.0139 17298256 (Pubitemid 46238955)
22. Continuous deep sedation in patients nearing death. SA Murray KIB Boyd, BMJ 2008 336 781-782
23. Palliative sedation: nurses' perceptions. AC Beel PG Hawranik S McClement P Daeninck, International Journal of Palliative Nursing 2006 12 11 510 518 17170668
24. Emotional burden of nurses in palliative sedation therapy. T Morita M Miyashita R Kimura I Adachi Y Shima, Palliative Medicine 2004 18 6 550 557 10.1191/0269216304pm911oa 15453626 (Pubitemid 39242801)
25. To die, to sleep: US physicians' religious and other objections to physician-assisted suicide, terminal sedation, and withdrawal of life support. FA Curlin C Nwodim JL Vance MH Chin JD Lantos, Am J Hosp Palliat Me 2008 25 2 112 120 10.1177/1049909107310141
26. Physicians' and pharmacists' attitudes toward the use of sedation at the end of life: influence of prognosis and type of suffering. D Blondeau L Roy S Dumont G Godin I Martineau, J Palliat Care 2005 21 4 238 245 16483092 (Pubitemid 43116684)
27. Having a difficult time leaving: experiences and attitudes of nurses with palliative sedation. JAC Rietjens J Hauser A van der Heide L Emanuel, Palliative Medicine 2007 21 7 643 649 10.1177/0269216307081186 17942505 (Pubitemid 350130915)
28. Physicians' and Nurses' Experiences With Continuous Palliative Sedation in the Netherlands. SJ Swart T Brinkkemper JAC Rietjens MH Blanker L van Zuylen M Ribbe WWA Zuurmond A van der Heide RSGM Perez, Archives of Internal Medicine 2010 170 14 1271 1274 10.1001/archinternmed.2010.226 20660851
29. Practices and attitudes of Japanese oncologists and palliative care physicians concerning terminal sedation: a nationwide survey. T Morita T Akechi Y Sugawara S Chihara Y Uchitomi, Journal of Clinical Oncology 2002 20 3 758 764 10.1200/JCO.20.3.758 11821458 (Pubitemid 34111383)
30. Relieving suffering at the end of life: practitioners' perspectives on palliative sedation from three European countries. JE Seymour R Janssens B Broeckaert, Social Science & Medicine 2007 64 8 1679 1691 (Pubitemid 46436240)
31. Exploration of concerns of relatives during continuous palliative sedation of their family members with cancer. S van Dooren HTM van Veluw L van Zuylen JAC Rietjens J Passchier CCD van der Rijt, Journal of Pain & Symptom Management 2009 38 3 452 459
32. Preferences for palliative sedation therapy in the Japanese general population. T Morita K Hirai Y Okazaki, J Palliat Med 2002 5 3 375 385 10.1089/109662102320135261 12133243 (Pubitemid 34620172)
33. Family experience with palliative sedation therapy for terminally ill cancer patients. T Morita M Ikenaga I Adachi I Narabayashi Y Kizawa Y Honke H Kohara T Mukaiyama T Akechi Y Uchitomi, et al. Journal of Pain & Symptom Management 2004 28 6 557 565 (Pubitemid 39626100)
34. The European Association for Palliative Care: Research Network, http://www.eapcnet.eu/Themes/Research/tabid/57/Default.aspx
35. Case study research methods in end-of-life care: reflections on three studies. S Payne D Field L Rolls S Hawker C Kerr, Journal of Advanced Nursing 2007 58 3 236 245 10.1111/j.1365-2648.2007.04215.x 17474912
36. Case studies - a research strategy appropriate for palliative care? C Walshe A Caress C Chew-Graham C Todd, Palliative Medicine 2004 18 677 684 10.1191/0269216304pm962ra 15623163 (Pubitemid 39654545)
37. European Charter for Family Carers. Confederation of family organisations in the European Union (COFACE), Brussels: European Commission 2007
38. Approaches to sampling and case selection in qualitative research: examples in the geography of health. S Curtis W Gesler G Smith S Washburn, Social Science & Medicine 2000 50 7-8 1001 1014 (Pubitemid 30055376)
39. Basics of qualitative research: Grounded theory procedures and techniques. A Strauss J Corbin, Newbury Park, CA: Sage 1990
40. Negotiating natural death in intensive care. JE Seymour, Soc Sci Med 2000 51 8 1241 1252 10.1016/S0277-9536(00)00042-3 11037214 (Pubitemid 30345512)
41. Social science and bioethics: the way forward. R de Vries L Turner K Orfali C Bosk, Sociology of Health & Illness 2006 28 6 665 677
42. Generalization in quantitative and qualitative research: Myths and strategies. DF Polit CT Beck, International Journal of Nursing Studies 2010 47 11 1451 1458 10.1016/j.ijnurstu.2010.06.004 20598692