Impaired splicing of fibronectin is associated with thoracic aortic aneurysm formation in patients with bicuspid aortic valve

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 31, Issue 3, 2011, Pages 691-697

  Paloschi, Valentina ^a   Kurtovic, Sanela ^a   Folkersen, Lasse ^a   Gomez, Delphine ^b   Wågsäter, Dick ^a   Roy, Joy ^c   Petrini, Johan ^d   Eriksson, Maria J ^d   Caidahl, Kenneth ^d   Hamsten, Anders ^a   Liska, Jan ^a   Michel, Jean Baptiste ^b   Franco Cereceda, Anders ^a   Eriksson, Per ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b INSERM   (France)

^c Vascular Surgery Section   (Sweden)

^d Clinical Physiology   (Sweden)

Author keywords

aneurysms; bicuspid aortic valve; fibronectin; splicing; thoracic aortic aneurysm

Indexed keywords

FIBRONECTIN; MESSENGER RNA; RNA; TRANSFORMING GROWTH FACTOR BETA;

ADULT; AGED; ARTICLE; ASCENDING AORTA; BICUSPID AORTIC VALVE; CELL CULTURE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; EXON; FEMALE; GENE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RNA SPLICING; SIGNAL TRANSDUCTION; SPLICEOSOME; THORACIC AORTA ANEURYSM; UPREGULATION;

AGED; AGED, 80 AND OVER; ALTERNATIVE SPLICING; AORTIC ANEURYSM, THORACIC; AORTIC VALVE; CASE-CONTROL STUDIES; CELLS, CULTURED; ECHOCARDIOGRAPHY, TRANSESOPHAGEAL; EXONS; FEMALE; FIBRONECTINS; GENE EXPRESSION PROFILING; GENETIC PREDISPOSITION TO DISEASE; HEART DEFECTS, CONGENITAL; HUMANS; MALE; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PRINCIPAL COMPONENT ANALYSIS; RNA, MESSENGER; SIGNAL TRANSDUCTION; SWEDEN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 79952196206     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.110.218461     Document Type: Article

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