Material separation in x-ray CT with energy resolved photon-counting detectors

Medical Physics

Volumn 38, Issue 3, 2011, Pages 1534-1546

  Wang, Xiaolan ^a   Meier, Dirk ^b   Taguchi, Katsuyuki ^a   Wagenaar, Douglas J ^c   Patt, Bradley E ^c   Frey, Eric C ^a,d  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Gamma Medica Ideas AS   (Norway)

^c Gamma Medica Ideas   (United States)

^d NONE   (United States)

Author keywords

CT; K edge; material separation; photon counting detectors; spectral CT

Indexed keywords

COMPUTERIZED TOMOGRAPHY; MERGERS AND ACQUISITIONS; PHANTOMS; PHOTONS; SEPARATION; TISSUE; VECTOR SPACES; X RAYS;

ATTENUATION COEFFICIENT; CLASSIFICATION METHODOLOGIES; LINEAR ATTENUATION COEFFICIENTS; MATERIAL SEPARATION; PHOTON COUNTING DETECTORS; PHYSICAL EXPERIMENTS; SIMULTANEOUS MEASUREMENT; X-RAY COMPUTED TOMOGRAPHY;

X RAY DETECTORS;

EID: 79952172950     PISSN: 00942405     EISSN: None     Source Type: Journal    
DOI: 10.1118/1.3553401     Document Type: Article

References (36)

1. W. A. Kalender, W. H. Perman, J. R. Vetter, and E. Klotz, " Evaluation of a prototype dual-energy computed tomographic apparatus. I. Phantom studies.," Med. Phys. 0094-2405 13, 334-339 (1986). 10.1118/1.595958 (Pubitemid 16062265)
2. W. Marshall, E. Hall, A. Doost-Hoseini, R. Alvarez, A. Macovski, and D. Cassel, " An implementation of dual energy CT scanning.," J. Comput. Assist. Tomogr. 0363-8715 8, 745-749 (1984). 10.1097/00004728-198408000-00029 (Pubitemid 14097070)
3. W. H. Marshall, Jr., R. E. Alvarez, and A. Macovski, " Initial results with prereconstruction dual-energy computed tomography (PREDECT).," Radiology 0033-8419 140, 421-430 (1981). (Pubitemid 11039972)
4. T. G. Flohr, C. H. McCollough, H. Bruder, M. Petersilka, K. Gruber, C. Suss, M. Grasruck, K. Stierstorfer, B. Krauss, R. Raupach, A. N. Primak, A. Kuttner, S. Achenbach, C. Becker, A. Kopp, and B. M. Ohnesorge, " First performance evaluation of a dual-source CT (DSCT) system.," Eur. Radiol. 0938-7994 16, 256-268 (2006). 10.1007/s00330-005-2919-2 (Pubitemid 43149624)
5. W. Pavlicek, P. Panse, A. Hara, T. Boltz, R. Paden, D. Yamak, P. Licato, N. Chandra, D. Okerlund, S. Dutta, R. Bhotika, and D. Langan, " Initial use of fast switched dual energy CT for coronary artery disease.," Proc. SPIE 0277-786X 7662, 76221V (2010). 10.1117/12.844859
6. R. E. Alvarez, J. A. Seibert, and S. K. Thompson, " Comparison of dual energy detector system performance.," Med. Phys. 0094-2405 31, 556-565 (2004). 10.1118/1.1645679 (Pubitemid 38381018)
7. R. A. Brooks and G. Di Chiro, " Split-detector computed tomography: A preliminary report.," Radiology 0033-8419 126, 255-257 (1978). (Pubitemid 8267058)
8. D. J. Drost and A. Fenster, " Experimental dual xenon detectors for quantitative CT and spectral artifact correction.," Med. Phys. 0094-2405 7, 101-107 (1980). 10.1118/1.594672 (Pubitemid 10147248)
9. G. M. Stevens and N. J. Pelc, " Depth-segmented detector for x-ray absorptiometry.," Med. Phys. 0094-2405 27, 1174-1184 (2000). 10.1118/1.598982 (Pubitemid 30350031)
10. A. H. Mahnken, S. Stanzel, and B. Heismann, " Spectral rhoZ-projection method for characterization of body fluids in computed tomography: Ex vivo experiments.," Acad. Radiol. 1076-6332 16, 763-769 (2009). 10.1016/j.acra.2009.01.002
11. A. N. Primak, J. C. Ramirez Giraldo, X. Liu, L. Yu, and C. H. McCollough, " Improved dual-energy material discrimination for dual-source CT by means of additional spectral filtration.," Med. Phys. 0094-2405 36, 1359-1369 (2009). 10.1118/1.3083567
12. M. Saito, " Spectral optimization for measuring electron density by the dual-energy computed tomography coupled with balanced filter method.," Med. Phys. 0094-2405 36, 3631-3642 (2009). 10.1118/1.3157098
13. J. P. Schlomka, E. Roessl, R. Dorscheid, S. Dill, G. Martens, T. Istel, C. Baumer, C. Herrmann, R. Steadman, G. Zeitler, A. Livne, and R. Proksa, " Experimental feasibility of multi-energy photon-counting K-edge imaging in pre-clinical computed tomography.," Phys. Med. Biol. 0031-9155 53, 4031-4047 (2008). 10.1088/0031-9155/53/15/002
14. P. M. Shikhaliev, " Tilted angle CZT detector for photon counting/energy weighting x-ray and CT imaging.," Phys. Med. Biol. 0031-9155 51, 4267-4287 (2006). 10.1088/0031-9155/51/17/010 (Pubitemid 44261844)
15. F. Arfelli, V. Bonvicini, A. Bravin, G. Cantatore, E. Castelli, L. Dalla Palma, M. Di Michiel, R. Longo, A. Olivo, S. Pani, D. Pontoni, P. Poropat, M. Prest, A. Rashevsky, G. Tromba, A. Vacchi, and E. Vallazza, " At the frontiers of digital mammography: SYRMEP.," Nucl. Instrum. Methods Phys. Res. A 0168-9002 409, 529-533 (1998). 10.1016/S0168-9002(97)01309-0 (Pubitemid 128414963)
16. E. Beuville, R. Cahn, B. Cederstrom, M. Danielsson, A. L. Hall, B. Hasegawa, L. Luo, M. Lundqvist, D. Nygren, E. Oltman, and J. Walton, " High resolution x-ray imaging using a silicon strip detector.," IEEE Trans. Nucl. Sci. 0018-9499 45, 3059-3063 (1998). 10.1109/23.737664 (Pubitemid 128741100)
17. T. O. Tumer, M. Clajus, G. I. Visser, S. Yin, P. D. Willson, L. D'Aries, K. B. Parnham, B. Glick, J. L. Perry, T. Gamble, G. Creede, E. Worthington, J. Sparling, D. Maeding, and D. Gorzen, " Preliminary results obtained from a novel CdZnTe pad detector and readout ASIC developed for an automatic baggage inspection system.," in IEEE Nuclear Science Symposium and Medical Imaging Conference Record, 2000 (unpublished).
18. R. A. Kruger, J. D. Armstrong, J. A. Sorenson, and L. T. Niklason, " Dual energy film subtraction technique for detecting calcification in solitary pulmonary nodules.," Radiology 0033-8419 140, 213-219 (1981). (Pubitemid 11067746)
19. M. M. Goodsitt, D. I. Rosenthal, W. R. Reinus, and J. Coumas, " Two postprocessing CT techniques for determining the composition of trabecular bone.," Invest. Radiol. 0020-9996 22, 209-215 (1987). 10.1097/00004424- 198703000-00005 (Pubitemid 17035212)
20. X. Liu, L. Yu, A. N. Primak, and C. H. McCollough, " Quantitative imaging of element composition and mass fraction using dual-energy CT: Three-material decomposition.," Med. Phys. 0094-2405 36, 1602-1609 (2009). 10.1118/1.3097632
21. G. J. Michael, " Tissue analysis using dual energy CT.," Australas. Phys. Eng. Sci. Med. 0158-9938 15, 75-87 (1992). (Pubitemid 23565756)
22. E. Roessl and R. Proksa, " K-edge imaging in x-ray computed tomography using multi-bin photon counting detectors.," Phys. Med. Biol. 0031-9155 52, 4679-4696 (2007). 10.1088/0031-9155/52/15/020 (Pubitemid 47103149)
23. D. P. Cormode, E. Roessl, A. Thran, T. Skajaa, R. E. Gordon, J. P. Schlomka, V. Fuster, E. A. Fisher, W. J. Mulder, R. Proksa, and Z. A. Fayad, " Atherosclerotic plaque composition: Analysis with multicolor CT and targeted gold nanoparticles.," Radiology 0033-8419 256, 774-782 (2010). 10.1148/radiol.10092473
24. R. E. Alvarez and A. Macovski, " Energy-selective reconstructions in x-ray computerized tomography.," Phys. Med. Biol. 0031-9155 21, 733-744 (1976). 10.1088/0031-9155/21/5/002
25. J. A. Victoreen, " The absorption of incident quanta by atoms as defined by the mass photoelectric absorption coefficient and the mass scattering coefficient.," J. Appl. Phys. 0021-8979 19, 855-860 (1948). 10.1063/1.1698220
26. M. J. Berger, J. H. Hubbell, S. M. Seltzer, J. Chang, J. S. Coursey, R. Sukumar, and D. S. Zucker, XCOM: Photon cross section database.
27. L. A. Lehmann, R. E. Alvarez, A. Macovski, W. R. Brody, N. J. Pelc, S. J. Riederer, and A. L. Hall, " Generalized image combinations in dual KVP digital radiography.," Med. Phys. 0094-2405 8, 659-667 (1981). 10.1118/1.595025 (Pubitemid 11004040)
28. T. R. Johnson, B. Krauss, M. Sedlmair, M. Grasruck, H. Bruder, D. Morhard, C. Fink, S. Weckbach, M. Lenhard, B. Schmidt, T. Flohr, M. F. Reiser, and C. R. Becker, " Material differentiation by dual energy CT: Initial experience.," Eur. Radiol. 0938-7994 17, 1510-1517 (2007). 10.1007/s00330-006-0517-6 (Pubitemid 46767599)
29. X. Wang, D. Meier, B. M. Sundal, P. ya, G. E. Maehlum, D. J. Wagenaar, B. M. W. Tsui, B. E. Patt, and E. C. Frey, " A digital line-camera for energy resolved x-ray photon counting.," in IEEE Nuclear Science Symposium and Medical Imaging Conference Record, Vol. M09-383, 2009 (unpublished).
30. W. P. Segars, M. Mahesh, T. J. Beck, E. C. Frey, and B. M. Tsui, " Realistic CT simulation using the 4D XCAT phantom.," Med. Phys. 0094-2405 35, 3800-3808 (2008). 10.1118/1.2955743
31. Z. He, W. Li, G. F. Knoll, D. K. Wehe, and Y. F. Du, " Effects of charge sharing in 3-D position sensitive CdZnTe gamma-ray spectrometers.," Nucl. Instrum. Methods Phys. Res. A 0168-9002 439, 619-624 (2000). 10.1016/S0168-9002(99)00841-4 (Pubitemid 30531314)
32. E. Kalemci and J. L. Matteson, " Investigation of charge sharing among electrode strips for a CdZnTe detector.," Nucl. Instrum. Methods Phys. Res. A 0168-9002 478, 527-537 (2002). 10.1016/S0168-9002(01)00892-0 (Pubitemid 34181591)
33. X. Wang, M. Dirk, J. Hugg, S. Chowdhury, D. J. Wagenaar, B. E. Patt, and E. C. Frey, " Modeling spectral distortions in energy resolved photon-counting x-ray detectors.," in Proceedings of the IEEE Nuclear Science Symposium and Medical Imaging Conference, Knoxville, TN, 2010 (unpublished).
34. E. C. Frey, X. Wang, Y. Du, K. Taguchi, J. Xu, and B. M. W. Tsui, " Investigation of the use of photon counting x-ray detectors with energy discrimination capability for material decomposition in micro-computed tomography.," Proc. SPIE 0277-786X 6510, 65100A (2007). 10.1117/12.711711 (Pubitemid 47550105)
35. P. M. Shikhaliev, " Beam hardening artefacts in computed tomography with photon counting, charge integrating and energy weighting detectors: A simulation study.," Phys. Med. Biol. 0031-9155 50, 5813-5827 (2005). 10.1088/0031-9155/50/24/004 (Pubitemid 41795835)
36. K. Taguchi, E. C. Frey, X. Wang, J. S. Iwanczyk, and W. C. Barber, " An analytical model of the effects of pulse pileup on the energy spectrum recorded by energy resolved photon counting x-ray detectors.," Med. Phys. 0094-2405 37, 3957-3969 (2010). 10.1118/1.3429056