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• A review article dealing with the use of polymyxins E and B in the critical care setting
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Michalopoulos A, Falagas ME. Colistin and polymyxin B in critical care. Crit Care Clin 2008;24(2):377-91 • A review article dealing with the use of polymyxins E and B in the critical care setting.
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Li J, Turnidge J, Milne R, et al. In vitro pharmacodynamic properties of colistin and colistin methanesulfonate against Pseudomonas aeruginosa isolates from patients with cystic fibrosis. Antimicrob Agents Chemother 2001;45:781-5
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Li J, Milne RW, Nation RL, et al. Pharmacokinetics of colistin methanesulphonate and colistin in rats following an intravenous dose of colistin methanesulphonate. J Antimicrob Chemother 2004;53(5):837-40 (Pubitemid 38660288)
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Li J, Coulthard K, Milne R, et al. Steady-state pharmacokinetics of intravenous colistin methanesulphonate in patients with cystic fibrosis. J Antimicrob Chemother 2003;52(6):987-92 (Pubitemid 38008420)
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•• An excellent review article dealing with the revival of colistin in clinical practice
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Li J, Nation RL, Turnidge JD, et al. Colistin: the re-emerging antibiotic for multidrug-resistant Gram-negative bacterial infections. Lancet Infect Dis 2006;6(9):589-601 •• An excellent review article dealing with the revival of colistin in clinical practice.
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Residue determination of two co-administered antibacterial agents - Cephalexin and colistin - in calf tissues using high-performance liquid chromatography and microbiological methods
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•• A recent study dealing with pharmacodynamic parameters of colistin against A. baumannii isolates
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Owen RJ, Li J, Nation RL, et al. In vitro pharmacodynamics of colistin against Acinetobacter baumannii clinical isolates. J Antimicrob Chemother 2007;59(3):473-7 •• A recent study dealing with pharmacodynamic parameters of colistin against A. baumannii isolates.
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•• A recent study dealing with in vitro pharmacodynamic parameters of colistin against MDR K. pneumoniae isolates
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Poudyal A, Howden BP, Bell JM, et al. In vitro pharmacodynamics of colistin against multidrug-resistant Klebsiella pneumoniae. J Antimicrob Chemother 2008;62(6):1311-18 •• A recent study dealing with in vitro pharmacodynamic parameters of colistin against MDR K. pneumoniae isolates.
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•• An excellent study which examined heteroresistance to colistin in MDR A. baumannii
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Li J, Rayner CR, Nation RL, et al. Hetero-resistance to colistin in multidrug-resistant Acinetobacter baumannii. Antimicrob Agents Chemother 2006;50:2946-50 •• An excellent study which examined heteroresistance to colistin in MDR A. baumannii.
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[Epub ahead of print] •• A recently published study which investigated PK/PD of colistin against P. aeruginosa
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Bergen PJ, Bulitta JB, Forrest A, et al. Pharmacokinetic (PK)/Pharmacodynamic (PD) investigation of colistin (C) against Pseudomonas aeruginosa (Pa) using an in vitro model. Antimicrob Agents Chemother 2010. [Epub ahead of print] •• A recently published study which investigated PK/PD of colistin against P. aeruginosa.
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Markou N, Markantonis SL, Dimitrakis E, et al. Colistin serum concentrations after intravenous administration in critically ill patients with serious multidrug-resistant, gram-negative bacilli infections: a prospective, open-label, uncontrolled study. Clin Ther 2008;30(1):143-51 •• This is the first study which examined serum concentrations of colistin in critically ill patients suffering from MDR Gram-negative bacilli infections in the ICU.
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Steady-state pharmacokinetics and bronchoalveolar lavage concentration of colistin in critically ill patients after intravenous colistin methanesulphonate administration
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[Epub ahead of print] •• This is study examined steady-state pharmacokinetics of colistin in critically ill patients after intravenous colistin methanesulphonate administration. It also examined concentration of colistin in bronchoalveolar lavage
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Imberti R, Cusato M, Villani P, et al. Steady-state pharmacokinetics and bronchoalveolar lavage concentration of colistin in critically ill patients after intravenous colistin methanesulphonate administration. Chest 2010. [Epub ahead of print] •• This is study examined steady-state pharmacokinetics of colistin in critically ill patients after intravenous colistin methanesulphonate administration. It also examined concentration of colistin in bronchoalveolar lavage.
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Lu Q, Girardi C, Zhang M, et al. Nebulized and intravenous colistin in experimental pneumonia caused by Pseudomonas aeruginosa. Intensive Care Med 2010;36(7):1147-55 •• An excellent study dealing with PK/PD data of nebulized and intravenous colistin against P. aeruginosa in experimental pneumonia.
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