Direct evidence for functional smooth muscle myosin II in the 10S self-inhibited monomeric conformation in airway smooth muscle cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 4, 2011, Pages 1421-1426

  Milton, Deanna L ^a   Schneck, Amy N ^a   Ziech, Dominique A ^a   Ba, Mariam ^a   Facemyer, Kevin C ^a   Halayko, Andrew J ^b   Baker, Jonathan E ^a   Gerthoffer, William T ^a,c   Cremo, Christine R ^a  

^a UNIVERSITY OF NEVADA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MANITOBA   (Canada)

^c UNIVERSITY OF SOUTH ALABAMA   (United States)

Author keywords

Cytoskeleton; Filament assembly; Myosin phosphorylation; Nuclear myosin II; Stress fibers

Indexed keywords

ALPHA TOXIN; EPITOPE; MONOMER; MYOSIN ANTIBODY; MYOSIN II;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PHOSPHORYLATION; SMOOTH MUSCLE FIBER; STRESS FIBER;

AMINO ACID SEQUENCE; BLOTTING, WESTERN; CELL LINE, TRANSFORMED; CELL MEMBRANE PERMEABILITY; CELLS, CULTURED; CYTOSKELETON; HUMANS; IMMUNOHISTOCHEMISTRY; MICROFILAMENTS; MICROSCOPY, CONFOCAL; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MYOCYTES, SMOOTH MUSCLE; MYOSIN TYPE II; PEPTIDES; PHOSPHORYLATION; PROTEIN CONFORMATION; RESPIRATORY SYSTEM; TOXINS, BIOLOGICAL;

EID: 79952145503     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1011784108     Document Type: Article

References (34)

1. Cremo CR, Hartshorne DJ (2008) Myosins: A Superfamily of Molecular Motors, ed Coluccio LM (Springer, Dordrecht, Netherlands), Vol 7, pp 171-222.
2. Onishi H, Wakabayashi T (1982) Electron microscopic studies of myosin molecules from chicken gizzard muscle I: The formation of the intramolecular loop in the myosin tail. J Biochem 92:871-879.
3. Trybus KM, Huiatt TW, Lowey S (1982) A bent monomeric conformation of myosin from smooth muscle. Proc Natl Acad Sci USA 79:6151-6155. (Pubitemid 13219823)
4. Kendrick-Jones J, Smith RC, Craig R, Citi S (1987) Polymerization of vertebrate non-muscle and smooth muscle myosins. J Mol Biol 198:241-252.
5. Trybus KM, Lowey S (1984) Conformational states of smooth muscle myosin. Effects of light chain phosphorylation and ionic strength. J Biol Chem 259:8564-8571. (Pubitemid 14090619)
6. Onishi H, Wakabayashi T, Kamata T, Watanabe S (1983) Electron microscopic studies of myosin molecules from chicken gizzard muscle II: The effect of thiophosphorylation of the 20K-dalton light chain on the ATP-induced change in the conformation of myosin monomers. J Biochem 94:1147-1154. (Pubitemid 14227241)
7. Trybus KM (1991) Assembly of cytoplasmic and smooth muscle myosins. Curr Opin Cell Biol 3:105-111.
8. Burgess SA, et al. (2007) Structures of smooth muscle myosin and heavy meromyosin in the folded, shutdown state. J Mol Biol 372:1165-1178. (Pubitemid 47374715)
9. Seow CY (2005) Myosin filament assembly in an ever-changing myofilament lattice of smooth muscle. Am J Physiol Cell Physiol 289:C1363-C1368.
10. Salinthone S, et al. (2007) Overexpression of human Hsp27 inhibits serum-induced proliferation in airway smooth muscle myocytes and confers resistance to hydrogen peroxide cytotoxicity. Am J Physiol Lung Cell Mol Physiol 293:L1194-L1207. (Pubitemid 350159404)
11. Watanabe S, et al. (2009) Expression of functional leukotriene B4 receptors on human airway smooth muscle cells. J Allergy Clin Immunol 124:59-65.
12. Sharma P, et al. (2008) Expression of the dystrophin-glycoprotein complex is a marker for human airway smooth muscle phenotype maturation. Am J Physiol Lung Cell Mol Physiol 294:L57-L68. (Pubitemid 351380318)
13. Redhu NS, et al. (2009) Proinflammatory and Th2 cytokines regulate the high affinity IgE receptor (FcepsilonRI) and IgE-dependant activation of human airway smooth muscle cells. PLoS ONE 4:e6153.
14. Tran T, et al. (2007) Laminin-binding integrin alpha7 is required for contractile phenotype expression by human airway myocytes. Am J Respir Cell Mol Biol 37:668-680. (Pubitemid 350211637)
15. Tran T, McNeill KD, Gerthoffer WT, Unruh H, Halayko AJ (2006) Endogenous laminin is required for human airway smooth muscle cell maturation. Respir Res 7:117-132.
16. Xia YC, et al. (2010) Functional expression of IgG-Fc receptors in human airway smooth muscle cells. Am J Respir Cell Mol Biol, 10.1165/rcmb.2009-0371OC.
17. Long X, Bell RD, Gerthoffer WT, Zlokovic BV, Miano JM (2008) Myocardin is sufficient for a smooth muscle-like contractile phenotype. Arterioscler Thromb Vasc Biol 28:1505-1510.
18. 2+ mobilization and contraction in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 293:L1406-L1418.
19. Gosens R, et al. (2007) Cooperative regulation of GSK-3 by muscarinic and PDGF receptors is associated with airway myocyte proliferation. Am J Physiol Lung Cell Mol Physiol 293:L1348-L1358. (Pubitemid 350159420)
20. Ikebe M, et al. (2001) The tip of the coiled-coil rod determines the filament formation of smooth muscle and nonmuscle myosin. J Biol Chem 276:30293-30300.
21. Horowitz A, Trybus KM, Bowman DS, Fay FS (1994) Antibodies probe for folded monomeric myosin in relaxed and contracted smooth muscle. J Cell Biol 126:1195-1200. (Pubitemid 24266551)
22. Li Q, Sarna, SK. (2009) Nuclear myosin II regulates the assembly of preinitiation complex for ICAM-1 gene transcription. Gastroenterology 137:1051-60 1060 e1-3.
23. Song L, et al. (1996) Structure of staphylococcal alpha-hemolysin, a heptameric transmembrane pore. Science 274:1859-1866. (Pubitemid 26424757)
24. Salzameda B, Facemyer KC, Beck BW, Cremo CR (2006) The N-terminal lobes of both regulatory light chains interact with the tail domain in the 10 S-inhibited conformation of smooth muscle myosin. J Biol Chem 281:38801-38811. (Pubitemid 46042007)
25. Olney JJ, Sellers JR, Cremo CR (1996) Structure and function of the 10 S conformation of smooth muscle myosin. J Biol Chem 271:20375-20384. (Pubitemid 26281805)
26. Katoh T, Kodama T, Fukushima A, Yazawa M, Morita F (1995) Evidence for involvement of a 12-residue peptide segment of the heavy chain in the neck region of smooth muscle myosin in formation of the 10S conformation. J Biochem 118:428-434.
27. Trybus KM, Lowey S (1988) The regulatory light chain is required for folding of smooth muscle myosin. J Biol Chem 263:16485-16492. (Pubitemid 18262069)
28. Xu JQ, Gillis JM, Craig R (1997) Polymerization of myosin on activation of rat anococcygeus smooth muscle. J Muscle Res Cell Motil 18:381-393.
29. Gillis JM, Cao ML, Godfraind-De Becker A (1988) Density of myosin filaments in the rat anococcygeus muscle, at rest and in contraction. II. J Muscle Res Cell Motil 9:18-29.
30. Watanabe M, Takemori S, Yagi N (1993) X-ray diffraction study on mammalian visceral smooth muscles in resting and activated states. J Muscle Res Cell Motil 14:469-475. (Pubitemid 23338715)
31. Shirinsky VP, et al. (1993) A kinase-related protein stabilizes unphosphorylated smooth muscle myosin minifilaments in the presence of ATP. J Biol Chem 268:16578-16583. (Pubitemid 23229968)
32. Gallagher PJ, Herring BP (1991) The carboxyl terminus of the smooth muscle myosin light chain kinase is expressed as an independent protein, telokin. J Biol Chem 266:23945-23952. (Pubitemid 21908889)
33. Herring BP, Smith AF (1996) Telokin expression is mediated by a smooth muscle cell-specific promoter. Am J Physiol 270:C1656-C1665. (Pubitemid 26303173)
34. Gosens R, et al. (2006) Role of caveolin-1 in p42/p44 MAP kinase activation and proliferation of human airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 291:L523-L534. (Pubitemid 44343730)