A common SCN5A polymorphism modulates the biophysical defects of SCN5A mutations

Heart Rhythm

Volumn 8, Issue 3, 2011, Pages 455-462

  Shinlapawittayatorn, Krekwit ^a   Du, Xi X ^a,b   Liu, Haiyan ^a   Ficker, Eckhard ^a   Kaufman, Elizabeth S ^a   Deschênes, Isabelle ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Case Western Reserve University   (United States)

Author keywords

Arrhythmia; Ion channels; Long QT syndrome; Mutation; Sodium; Sudden death

Indexed keywords

SODIUM CHANNEL NAV1.5;

ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; DNA POLYMORPHISM; GENE EXPRESSION; GENE INACTIVATION; GENE MUTATION; HUMAN; HUMAN CELL; LONG QT SYNDROME; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; SODIUM CURRENT;

ADOLESCENT; ARRHYTHMIAS, CARDIAC; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HEK293 CELLS; HUMANS; ION CHANNEL GATING; LONG QT SYNDROME; MUTAGENESIS, SITE-DIRECTED; MUTATION; PATCH-CLAMP TECHNIQUES; PEDIGREE; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, DNA; SODIUM CHANNELS;

EID: 79952142077     PISSN: 15475271     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hrthm.2010.11.034     Document Type: Article

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