Experimental research on the management of combined radiation-burn injury in China

Radiation Research

Volumn 175, Issue 3, 2011, Pages 382-389

  Ran, Xin Ze ^a   Shi, Chun Meng ^a   Zheng, Huai En ^a   Su, Yong Ping ^a   Cheng, Tian Min ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2 (3 AMINO PROPYLAMINE)ETHYL THIOPHOSPHORIC ACID; BETA DEFENSIN 5; CHITOSAN; E 838; ESTROGEN DERIVATIVE; GLUCAGON LIKE PEPTIDE 2; INTERLEUKIN 3; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; LIDOCAINE; PHOSPHOROTHIOIC ACID DERIVATIVE; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VERAPAMIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL INFECTION; BLOOD RADIATION; BURN; CELL REGENERATION; CHINA; CONTROLLED STUDY; FLUID THERAPY; HEART DISEASE; HEART FUNCTION; HEMATOPOIESIS; HEMATOPOIETIC CELL; IMMUNITY; MEDICAL RESEARCH; NERVE BLOCK; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INJURY; SHOCK; SKIN GRAFT; SURVIVAL; SYMPATHETIC GANGLION;

ANIMALS; BURNS; CHINA; HUMANS; INFECTION CONTROL; RADIATION INJURIES;

ANIMALIA; BACTERIA (MICROORGANISMS);

EID: 79952139328     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/RR2198.1     Document Type: Article

References (72)

1. T. M. Cheng, C. J. Luo and Y. T. Yan, Chief Eds., Radiation Medicine, pp. 41-57. Shanghai S & T Publisher, Shanghai, 1986.
2. T. M. Cheng, R. Li, Y. P. Su, H. Xu and G. P. Ai, Depleted uranium weapon injuries and their medical protection. Med. J. Chin. PLA 30, 549-551 (2005).
3. A. L. DiCarlo, R. J. Hatchett, J. M. Kaminski, G. D. Ledney, T. C. Pellmar, P. Okunieff and N. Ramakrishnan, Medical countermeasures for radiation combined injury: radiation with burn, blast, trauma and/or sepsis. Report of an NIAID Workshop, March 26-27, 2007. Radiat. Res. 169, 712-721 (2008). (Pubitemid 351793461)
4. Z. Zou, H. Sun, Y. Su, T. Cheng and C. Luo, Progress in research on radiation combined injury in China. Radiat. Res. 169, 722-729 (2008). (Pubitemid 351793462)
5. R. S. Budagov and L. P. Ul'ianova, Effects of modulators of cytokine levels on mice and rats survival under combined radiation/thermal injuries. Radiat. Biol. Radioecol. 44, 392-397 (2004).
6. C. J. Luo and Y. P. Su, Eds., Combined Injury, pp. 1-10. Military Medical Science Press, Beijing, 2006.
7. P. Kumar and G. C. Jagetia, A review of triage and management of burns victims following a nuclear disaster. Burns 20, 397-402 (1994). (Pubitemid 24289357)
8. G. D. Ledney, E. D. Exum and P. A. Sheehy, Survival enhanced by skin-wound trauma in mice exposed to 60Co radiation. Experientia 37, 193-194 (1981). (Pubitemid 11188010)
9. G. D. Ledney, E. D. Exum, D. A. Stewart, H. M. Gelston Jr. and S. R. Weinberg, Survival and hematopoietic recovery in mice after wound trauma and whole-body irradiation. Exp. Hematol. 10 (Suppl. 12), 263-278 (1982).
10. J. G. Kiang, W. Jiao, L. H. Cary, S. R. Mog, T. B. Elliott, T. C. Pellmar and G. D. Ledney, Wound trauma increases radiationinduced mortality by activation of iNOS pathway and elevation of cytokine concentrations and bacterial infection. Radiat. Res. 173, 319-332 (2010).
11. J. G. Kiang, B. R. Garrison and N. V. Gorbunov, radiation combined injury: DNA damage, apoptosis, and autophagy. Adapt. Med. 2, 1-10 (2010).
12. J. D. Reid, J. W. Brooks, W. T. Ham and E. I. Evans, The influence of X-radiation on mortality following thermal flash burns: The site of tissue injury as a factor determining the type of invading bacteria. Ann. Surg. 142, 844-850 (1955).
13. Y. P. Su, T. M. Cheng, X. Z. Ran and Y. Lin, Effect of early stage shock in combined radiation-burn on whole body and intestinal epithelium of mice. Chin. J. Trauma 9, 258-260 (1993).
14. B. Ye, T. Cheng, J. Xiao, X. Zeng, Z. Liu, Y. Guo and H. Xie, Effects of different components of serum from radiation, burn and combined radiation-burn injury on L-type calcium channel of cultured myocardial cells. Zhongguo Ying Yong Sheng Li Xue Za Zhi 13, 231-234 (1997).
15. B. L. Ye, T. M. Cheng, J. S. Xiao, X. R. Zeng, Z. F. Liu, Y. Guo and H. F. Xie, Effects of different components of serum after radiation, burn and combined radiation-burn injury on inward rectifier potassium channel of myocardial cells. Chin. J. Radiol. Med. Prot. 17, 225-229 (1997).
16. H. Xu and Z. R. Chen, Changes of b-adrenoceptor concentration in myocardial membrane of rats subjected to combined radiationburn injury. Chin. J. Radiol. Med. Prot. 16, 81-84 (1996).
17. W. D. Wang, Z. R. Chen and R. Li, Dynamic changes of myocardial nitric oxide formation and cGMP content in the early stage after radiation, burn and combined radiation-burn injuries in rats. J. Med. Coll. PLA 13, 11-14 (1998).
18. Y. Xiong, Z. R. Chen and T. M. Cheng, Protective effects of verapamil on myocardial mitochondrial respiratory function after combined radiation-burn injury in rats. J. Med. Coll. PLA 11, 11-13 (1996).
19. Y. Xiong, Z. R. Chen and T. M. Cheng, Effects of exogenous calcium on myocardial mitochondrial respiratory function at the early stage after combined radiation-burn injury in rats. Acta Acad. Med. Mil. Tert. 19, 93-97 (1997).
20. Y. Xiong and Z. R. Chen, Abnormal calcium transport of myocardial mitochondria during the early stage of combined radiation-burn injury in rats. J. Med. Coll. PLA 11, 244-249 (1996).
21. T. M. Cheng and S. Z. Zhou, Several issues of acute combined radiation-burn injury complicated by infection in dogs. In Archives of the Research, Teaching and Administration of Academician Cheng Tiam-min, pp. 167-173. People's Military Medical Press, Beijing, 2006.
22. X. G. Chu, Y. T. Yan, Q. J. He and T. M. Cheng, Experimental study of extremely severe combined radiation-burn injury in dogs. Chin. J. Radiol. Med. Prot. 8, 107-110 (1988).
23. C. X. Shu, Z. R. Chen and S. B. Wang, Studies of the changes of the phagocytic function of polymorphonuclear leucocytes and the mechanism after combined radiation-burn injury in rats. Acta Acad. Med. Mil. Tert. 17, 24-28 (1995).
24. Y. T. Yan, X. Z. Ran and S. Q. Wei, Changes of immune functions after radiation, burns and combined radiation-burn injury in rats. Chin. Med. Sci. J. 10, 85-89 (1995).
25. X. Z. Ran, Y. T. Yan and S. Q. Wei, Effect of auto-skin grafting on bacterial infection of wound in rats inflicted with combined radiation-burn injury. Chin. J. Radiol. Med. Prot. 12, 380-382 (1992).
26. Y. T. Yan, X. Z. Ran, S. Q. Wei, T. M. Cheng, Y. Zhang and X. H. Liu, Evaluation of different means of wound treatment for severe combined radiation-burn injury in rats. Chin. J. Radiol. Med. Prot. 11, 312-315 (1991).
27. G. P. Ai, Y. P. Su, X. H. Liu, T. M. Cheng and X. Z. Ran, Recovery of impaired intestinal mucosal immune function by recombinant human interleukin 4 in several types of injuries in mice. Acta Acad. Med. Mil. Tert. 21, 1-4 (1999).
28. J. D. Zhu, Y. P. Su and T. M. Cheng, Effect of glucagon-like peptide 2 on recovery of intestinal function from radiation injury in mice. Chin. J. Radiol. Med. Prot. 22, 30-32 (2002).
29. T. Wang, G. P. Ai, Z. Y. Du, H. Tan and Y. P. Su, Treatment for mice with minor gastrointestinal type combined radiation and burn injury. Acta Acad. Med. Mil. Tert. 27, 2099-2102 (2005).
30. L. Tu, H. L. Fang, Y. P. Su, G. P. Ai, X. Li, M. Li, Y. Chen, Y. Y. Huang and J. M. Xu, Influence of cervical sympathetic nerve block on blood flow volume and barrier function of intestinal mucosa after combined radiation and burn injury in rat. Zhonghua Shao Shang Za Zhi 23, 208-211 (2007). (Pubitemid 47249502)
31. L. Tu, H. L. Fang, X. Li, M. Li and Y. Chen, Effect of SB on intestinal mucosal blood flow volume and ATPase from combined radiation and burn injury in rat. Mod. Med. Health 22, 2258-2259 (2006).
32. J. H. Lu, J. Tao, J. N. Ye, Y. P. Su, H. T. Li and T. M. Cheng, Effect of cervical sympathetic ganglia block on HPA axis in mice with combined radiation and burn injury and its related mechanisms. Acta Acad. Med. Mil. Tert. 28, 2111-2114 (2006).
33. J. H. Lu, Y. P. Su, J. Tao and J. N. Ye, Effects of cervical sympathetic ganglia block on GR expression and cytokine release of macrophage in mice with combined radiation and burn injury. Acta Acad. Med. Mil. Tert. 29, 284-286 (2007).
34. J. H. Lu, Y. P. Su, T. M. Cheng and Y. Du, Roles of cervical sympathetic ganglia block in the treatment of mice with combined radiation and burn injury. Acta Acad. Med. Mil. Tert. 27, 1253-1255 (2005).
35. C. J. Luo, J. X. Zheng and X. Z. Ran, The impact of combined radiation-burn injury on granulocyte-lineage hematopoiesis. Acta Acad. Med. Mil. Tert. 5, 119-122 (1983).
36. J. X. Zheng, D. Y. Qi, J. L. Zeng, G. J. Fu and B. X. Teng, Causes of anemia in radiation injury and combined radiationburn injury during recovery phase. Chin. J. Radiol. Med. Prot. 7, 177-180 (1987).
37. X. H. Chen, C. J. Luo, C. H. Guo and P. Wang, Capacity of bone marrow colony forming unit-fibroblasts from mice with combined radiation burn injury. Chin. J. Radiol. Med. Prot. 19, 22-23 (1999).
38. C. J. Luo, Z. M. Zou, X. H. Chen, P. Y. Kong, C. H. Guo and Y. H. Zhou, Study on the mechanism of hematopoietic malfunction and reconstruction of the hematopoietic system in the combined radiation and thermal injury. Chin. J. Dis. Control Prev. 8, 66-67 (2004).
39. H. T. Huang, C. J. Luo, C. H. Guo and Y. H. Zhou, Effects of combined radiation burn injury on thrombopoietin gene expression of bone marrow stromal cells in mice. Acta Acad. Med. Mil. Tert. 21, 648-650 (1999).
40. C. H. Guo, C. J. Luo, P. Y. Kong, Y. H. Zhou, Z. M. Zou and Y. Shi, Effect of bone marrow stromal cells on the growth of granulocyte-macrophage progenitor cells in mice with combined radiation-burn Injury. Chin. J. Exp. Hematol. 7, 65-68 (1999).
41. C. J. Luo, C. H. Guo, Y. H. Zhou and X. Liu, Effects of interleukin-3 on hemopoietic function after combined radiationburn injury in mice. Chin. J. Radiol. Med. Prot. 16, 28-31 (1996).
42. M. Z. Liang, C. J. Luo, C. H. Guo and Y. H. Zhou, Effects of rhGM-CSF on treatment of combined radiation-burn injury in mice. J. Radiat. Res. Radiat. Process. 17, 170-173 (1999).
43. W. Jiang and C. J. Luo, Regulative effects of tumor necrosis factor a on granulocyto-monocytopoiesis after combined radiation burn injury in mice. Acta Acad. Med. Mil. Tert. 19, 234-236 (1997).
44. Y. Shi, C. H. Guo, Z. W. Wang, Y. H. Zhou and C. J. Luo, Protective effect of WR-2721 on the combined radiation-burn injury in mice. J. Radiat. Res. Radiat. Process. 16, 225-230 (1998).
45. Q. J. He, Study of radioprotective effects of WR-2721 on peritoneal macrophages after combined radiation-burn injury in mice. Acta Acad. Med. Mil. Tert. 16, 188-190 (1994).
46. X. H. Liu and Y. Shi, Effects of WR2721 on MDA, SOD and DNA of bone marrow and spleen in mice following combined radiation-burn injury. Acta Acad. Med. Mil. Tert. 16, 141-142 (1994).
47. Y. Shi, C. H. Guo, X. H. Liu, R. Li, Y. H. Zhou and C. J. Luo, Comparison study on the effects of several anti-radiation drugs on simple radiation sickness and combined radiation-burn injury. Chin. J. Radiol. Med. Prot. 19, 280-281 (1999).
48. C. J. Luo, Y. Shi and C. H. Guo, Protective effect of WR2721 and fetal liver cell transplantation on combined radiation-burn injury in mice. Acta Acad. Med. Mil. Tert. 8, 342-346 (1986).
49. C. H. Guo, Y. H. Zhou, Z. M. Zou, P. Y. Kong, C. M. Shi, J. M. Zhou, X. Z. Ran, Y. P. Su and C. J. Luo, Experimental study of E838 applied in combined radiation burn injury. Acta Acad. Med. Mil. Tert. 23, 627-629 (2001).
50. Z. M. Zou, C. H. Guo, C. M. Shi, B. Zhu, J. M. Zhou, Y. H. Zhou, Y. Zhang, C. J. Luo and T. M. Cheng, The protective effect of E838 on hematopoiesis of compound radiation-burn injured mice. Chongqing Med. 30, 313-314 (2001).
51. C. H. Guo, P. Y. Kong, Z. M. Zou, Y. H. Zhou, J. M. Zhou, Y. Zhang, C. M. Shi, X. Z. Ran and C. J. Luo, Experimental study on preventive and therapeutic effects of 5 radioprotectants on combined radiation-burn injured mice. Acta Acad. Med. Mil. Tert. 23, 544-546 (2001).
52. X. Z. Ran, Y. P. Su, Z. W. Zong, C. H. Guo, H. E. Zheng, X. H. Chen, G. P. Ai and T. M. Cheng, Effects of serum from rats with combined radiation-burn injury on the growth of hematopoietic progenitor cells. J. Trauma. 62, 193-198 (2007).
53. X. Z. Ran, Y. P. Su, Z. W. Zong, C. M. Shi, C. H. Guo, A. P. Wang, G. H. Yan, S. W. Dong and T. M. Cheng, Effects of peritoneal lavage fluid from radiation or/and burn injured rats on the growth of hematopoietic progenitor cells. Int. J. Radiat. Biol. 84, 499-504 (2008).
54. T. M. Cheng and Z. M. Zou, Recent advances in the research of radiation combined injury. Chin. J. Radiol. Med. Prot. 18, 299-303 (1998).
55. Q. Y. Zhao, T. X. Liu and J. F. Gao, Prevention and treatment of severe combined radiation-burn injury. Bull. Acad. Mil. Med. Sci. 4, 217-224 (1980).
56. X. Ran, Y. Yan and Y. Lin, Effects of locally used SD zinc, SD silver and skin transplantation on the combined radiation-burn injury in the rat. Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi 13, 330-334 (1997).
57. J. F. Song, S. F. Lou, Z. P. Yu and T. M. Cheng, Therapeutic effect of topically applied iodophor and phenytoin on combined radiation-burn wounds in rats. Acta Acad. Med. Mil. Tert. 21, 390-393 (1999).
58. J. Zheng, S. Wang, L. Guo, S. Qu and D. A. Yan, Promotion of wound healing with fibroblast growth factor in combined burn radiation injury. Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi 10, 146-149 (1994).
59. J. X. Zheng, S. H. Wang, D. A. Yan, L. L. Guo and F. X. Shi, A study on the factors influencing bFGF to improve wound healing in severe combined burn-radiation injury. J. First Mil. Med. Univ. 14, 191-193 (1994).
60. Y. T. Yan, X. Z. Ran, S. Q. Wei and T. M. Cheng, Different methods for wound management of rats with combined radiation-burn injury. Chin. Med. J. 106, 504-508 (1993).
61. H. E. Zheng, T. M. Cheng, Y. Lin, D. Q. Gu and Y. T. Yan, Pathological changes in allogenic skin in combined radiationburn injury in rats. Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi 7, 116-118 (1991).
62. X. Z. Ran, Y.T. Yan, T. M. Cheng, Y. Lin and S. Q. Wei, Experimental study on the manipulation of small wound surface of combined radiation-burn injury. Chin. Med. J. 77, 154-156 (1997).
63. Y. T. Yan, X. Z. Ran and S. Q. Wei, Effects of blood transfusion and skin grafting on rats with combined radiation-burn injury. Chin. J. Radiol. Med. Prot. 10, 32-35 (1990).
64. Y. T. Yan, X. Z. Ran and S. Q. Wei, Effects of transfusion with stored blood after combined radiation-burn injury on immune reaction of allo-skin grafted rats. Chin. J. Blood Transfus. 6, 61-65 (1993).
65. X. Z. Ran, Y. T. Yan, S. Q. Wei and T. M. Cheng, Effect of different kinds of blood transfusion on immune response in combined radiation-burn injury with allo-dermal grafting in rats. Chin. J. Radiol. Med. Prot. 13, 182-186 (1993).
66. X. Z. Ran, Y. T. Yan, T. M. Cheng, Y. Lin, S. Q. Wei and H. E. Zheng, Effects of the combined radiation and thermal injury on the survival of skin allograft and immune function in rats. Chin. Med. J. 111, 634-637 (1998). (Pubitemid 128515526)
67. Y. T. Yan, S. Q. Wei, X. Z. Ran and H. E. Zheng, Effect of skin grafting at different time on the rats with combined radiationburn injury after blood transfusion and bone marrow transplantation. Chin. J. Organ Transplant. 11, 22-24 (1990).
68. X. Z. Ran, Y. T. Yan, T. M. Cheng, Y. Lin, H. E. Zheng and S. Q. Wei, The effect of skin grafting at different time post blood transfusion and bone marrow transplantation on rats combined radiation-burn injury. Chin. Med. Sci. J. 13, 112-115 (1998).
69. H. E. Zheng, T. M. Cheng, Y. T. Yan, X. Z. Ran, S. Q. Wei, Y. Lin, D. Q. Gu and G. H. Yan, Pathological changes after bone marrow and skin allograft transplantation in rats inflicted with severe combined radiation burn injury. Chin. J. Radiol. Med. Prot. 14, 83-85 (1994).
70. J. F. Weiss and M. R. Landauer, History and development of radiation-protective agents. Int. J. Radiat. Biol. 85, 539-573 (2009).
71. S. J. Hosseinimehr, V. Zakaryaee and M. Froughizadeh, Oral oxymetholone reduces mortality induced by gamma irradiation in mice through stimulation of hematopoietic cells. Mol. Cell. Biochem. 287, 193-199 (2006). (Pubitemid 44057407)
72. M. Jin, H. Jeon, H. J. Jung, B. Kim, S. S. Shin, J. J. Choi, J. K. Lee, C. Y. Kang and S. Kim, Enhancement of repopulation and hematopoiesis of bone marrow cells in irradiated mice by oral administration of PG101, a water-soluble extract from Lentinus lepideus. Exp. Biol. Med. 228, 759-766 (2003). (Pubitemid 37163268)