Antifungal dose adjustment in renal and hepatic dysfunction: Pharmacokinetic and pharmacodynamic considerations

Current Fungal Infection Reports

Volumn 4, Issue 2, 2010, Pages 120-128

  Cota, Jason M ^a   Burgess, David S ^b  

^a UNIVERSITY OF THE INCARNATE WORD   (United States)

^b NONE

Author keywords

Antifungal drugs; Dosage; Echinocandins; Kidney dysfunction; Liver dysfunction; Renal replacement therapy; Triazoles

Indexed keywords

AMPHOTERICIN B; AMPHOTERICIN B DEOXYCHOLATE; ANIDULAFUNGIN; ANTIFUNGAL AGENT; CASPOFUNGIN; CREATININE; CYCLODEXTRIN; ECHINOCANDIN; FLUCONAZOLE; FLUCYTOSINE; MICAFUNGIN; POLYSULFONE; POSACONAZOLE; TRIAZOLE DERIVATIVE; VORICONAZOLE;

ANTIFUNGAL ACTIVITY; AREA UNDER THE CURVE; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; BONE MARROW DEPRESSION; BRAIN DISEASE; CANDIDA; CANDIDIASIS; CONTINUOUS HEMODIAFILTRATION; CONTINUOUS RENAL REPLACEMENT THERAPY; CREATININE CLEARANCE; CRITICALLY ILL PATIENT; CRYPTOCOCCAL MENINGITIS; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DISPOSITION; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG MEGADOSE; DRUG METABOLISM; DRUG PROTEIN BINDING; DRUG SAFETY; DRUG TOLERABILITY; HEMODIALYSIS; HUMAN; IN VIVO STUDY; KIDNEY DISEASE; LIVER DISEASE; LIVER TOXICITY; MINIMUM INHIBITORY CONCENTRATION; NEPHROTOXICITY; NEUROTOXICITY; NONHUMAN; PRACTICE GUIDELINE; RANDOMIZED CONTROLLED TRIAL (TOPIC); RENAL REPLACEMENT THERAPY; REVIEW; SINGLE DRUG DOSE; TOXICOKINETICS; TREATMENT OUTCOME; TREATMENT RESPONSE; UNSPECIFIED SIDE EFFECT;

EID: 79952138365     PISSN: 19363761     EISSN: 1936377X     Source Type: Journal    
DOI: 10.1007/s12281-010-0015-9     Document Type: Review

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